Cytokine mRNA profiles for isocyanates with known and unknown potential to induce respiratory sensitization

Toxicology

Volumn 207, Issue 3, 2005, Pages 487-499

  Plitnick, L M ^a,e   Loveless, S E ^b   Ladics, G S ^b   Holsapple, M P ^c   Smialowicz, R J ^d   Woolhiser, M R ^c   Anderson, P K ^c   Smith, C ^b   Selgrade, M J K ^d  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b DUPONT COMPANY   (United States)

^c DOW CHEMICAL COMPANY   (United States)

^d U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^e MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Cytokines; Diisocyanate; Hypersensitivity; Respiratory sensitizers; Ribonuclease protection assay; Th1 and Th2 cells

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; CYTOKINE; DIPHENYLMETHANE 4,4' DIISOCYANATE; ISOCYANIC ACID DERIVATIVE; MESSENGER RNA; TOLUENE DIISOCYANATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; EXPOSURE; FEMALE; IMMUNE RESPONSE; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RESPIRATORY FUNCTION; RIBONUCLEASE PROTECTION ASSAY; SENSITIZATION; TH2 CELL;

ALLERGENS; ANIMALS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION; HUMANS; ISOCYANATES; LOCAL LYMPH NODE ASSAY; LYMPH NODES; MICE; MICE, INBRED BALB C; MICE, INBRED CBA; RESPIRATORY HYPERSENSITIVITY; RIBONUCLEASES; RNA, MESSENGER; SKIN; TH1 CELLS; TH2 CELLS;

EID: 12344260785     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2004.11.001     Document Type: Article

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