Allergen-induced cytokine phenotypes in mice: Role of CD4+ and CD8+ T cell populations

Clinical and Experimental Allergy

Volumn 35, Issue 4, 2005, Pages 498-505

  Dearman, Rebecca J ^a   Humphreys, N ^a   Skinner, R A ^a   Kimber, I ^a  

^a JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

Author keywords

Cytokines; Flow cytometry; Mouse model; Respiratory allergy; T cell subsets

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; ALLERGEN; CD4 ANTIGEN; CD8 ANTIGEN; CHEMICAL AGENT; CYTOKINE; FLUORESCEIN ISOTHIOCYANATE; FORMALDEHYDE; GAMMA INTERFERON; INTERLEUKIN 4; TRIMELLITIC ANHYDRIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNE RESPONSE; LYMPH NODE; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; RESPIRATORY TRACT ALLERGY; T LYMPHOCYTE SUBPOPULATION;

ALLERGENS; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; DINITROCHLOROBENZENE; FEMALE; FLUORESCEIN-5-ISOTHIOCYANATE; FORMALDEHYDE; INTERFERON TYPE II; INTERLEUKIN-4; LYMPHOCYTE COUNT; MICE; MICE, INBRED BALB C; PHENOTYPE; PHTHALIC ANHYDRIDES; RESPIRATORY HYPERSENSITIVITY;

EID: 17744397362     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2005.02209.x     Document Type: Article

References (39)

1. Sastre J, Vandenplas O, Park HS. Pathogenesis of occupational asthma. Eur Respir J 2003; 22:364-73.
2. Wild LG, Lopez M. Occupational asthma caused by high-molecular-weight substances. Immunol Allergy Clin North Am 200; 23:235-50.
3. Frew AJ. What can we learn about asthma from studying occupational asthma? Ann Allergy Asthma Immunol 2003; 90:7-10.
4. Topping MD, Venables KM, Luczynska CM, Howe W, Newman Taylor AJ. Specificity of the human IgE response to inhaled acid anhydrides. J Allergy Clin Immunol 1986; 77:834-42.
5. Czuppon AB, Merget R, Raulf-Heimsoth M, Bruening T. Comparison of IgE antibody concentrations to pyromellitic dianhydride-modified laminin and human serum albumin in sera of exposed workers with respiratory complaints. Int Arch Allergy Immunol 2002; 127:79-81.
6. Tee RD, Cullinan P, Welch J, Burge PS, Newman Taylor AJ. Specific IgE antibody to isocyanates: a useful diagnostic role in occupational asthma. J Allergy Clin Immunol 1998; 101:709-15.
7. Wass U, Belin L. Immunological specificity of isocyanate-induced IgE antibodies in serum from 10 sensitized workers. J Allergy Clin Immunol 1989; 83:126-35.
8. Mapp C, Boschetto P, Miotto D, D e Rosa E, Fabbri LM. Mechanisms of occupational asthma. Ann Allergy Asthma Immunol 1999; 83:645-64.
9. Larche M, Robinson DS, Kay AB. The role of T lymphocytes in the pathogenesis of asthma. J Allergy Clin Immunol 2003; 111:450-63.
10. Bentley AM, Maestrelli P, Saetta M et al. Activated T lymphocytes and eosinophils in the bronchial mucosa in isocyanate-induced asthma. J Allergy Clin Immunol 1992; 89:821-9.
11. Del Prete GF, De Carli M, D'Elios MM et al. Allergen exposure induces the activation of allergen-specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders. Eur J Immunol 1993; 23:1445-9.
12. + cells. Adv Immunol 1989; 46:111-47.
13. + T cells secreting Th1 or Th2 cytokines. Immunity 1995; 2:271-9.
14. Durham SR, Till SJ, Corrigan CJ. T lymphocytes in asthma: bronchial vs. peripheral responses. J Allergy Clin Immunol 2000; 106:S221-6.
15. Ying S, Humbert M, Barkans J et al. Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics. J Immunol 1997; 158:3539-44.
16. Till S, Dickason R, Huston D et al. IL-5 secretion by allergen-stimulated CD4+ T cells in primary culture: relationship to expression of allergic disease. J Allergy Clin Immunol 1997; 99:563-9.
17. O'Brien RM, Xu H, Rolland JM, Byron KA, Thomas WR. Allergen-specific production of interferon-gamma by peripheral blood mononuclear cells and CD8 T cells in allergic disease and following immunotherapy. Clin Exp Allergy 2000; 30:333-40.
18. Magnan AO, Mely LG, Camilla CA et al. Assessment of the Th1/Th2 paradigm in whole blood in atopy and asthma. Increased IFN-gamma-producing CD8(+) T cells in asthma. Am J Respir Crit Care Med 2000; 161:1790-6.
19. Cho SH, Stanciu LA, Begishivili T, Bates PJ, Holgate ST, Johnston SL. Peripheral blood CD4+ and CD8+ T cell type 1 and type 2 cytokine production in atopic asthmatic and normal subjects. Clin Exp Allergy 2002; 32:427-33.
20. Maestrelli P, Del Prete GF, De Carli M et al. CD8 T-cell clones producing interleukin-5 and interferon-gamma in bronchial mucosa of patients with asthma induced by toluene diisocyanate. Scand J Work Environ Health 1994; 20:376-81.
21. Zeiss CR, Patterson R, Pruzansky JJ, Miller M, Rosenberg M, Levitz D. Trimellitic anhydride-induced airway syndromes: clinical and immunologic studies. J Allergy Clin Immunol 1977; 60:96-103.
22. Dearman RJ, Warbrick EV, Skinner R, Kimber I. Cytokine fingerprinting of chemical allergens: species comparisons and statistical analyses. Food Chem Toxicol 2002; 40:1881-92.
23. + T helper 2-type cells in cutaneous inflammatory responses induced by fluorescein isothiocyanate. Immunology 2000; 101:442-51.
24. + T lymphocyte subsets to the cytokine secretion patterns induced in mice during sensitization to contact and respiratory chemical allergens. Immunology 1996; 89:502-10.
25. Chrest FJ, Buchholz MA, Kim YH, Kwon TK, Nordin AA. Identification and quantification of apoptotic cells following anti-CD3 activation of murine G0 T cells. Cytometry 1993; 14:883-90.
26. Herrick CA, Das J, Xu L, Wisnewski AV, Redlich CA, Bottomly K. Differential roles for CD4 and CD8T cells after diisocyanate sensitization: genetic control of TH2-induced lung inflammation. J Allergy Clin Immunol 2003; 111:1087-94.
27. Tang M, Kemp A. Production and secretion of interferon-gamma (IFN-gamma) in children with atopic dermatitis. Clin Exp Immunol 1994; 95:66-72.
28. Anderson SJ, Coleclough C. Regulation of CD4 and CD8 expression on mouse T cells. Active removal from the cell surface by two mechanisms. J Immunol 1993; 151:5123-34.
29. Bancroft AJ, McKenzie ANJ, Grencis R. A critical role for IL-13 in resistance to intestinal nematode infection. J Immunol 1998; 160:3453-61.
30. Moussavi A, Dearman RJ, Kimber I, Kemeny DM. Cytokine production by CD4+ and CD8+ T cells in mice following primary exposure to chemical allergens: evidence for functional differentiation of T lymphocytes in vivo. Int Arch Allergy Immunol 1998; 116:116-23.
31. Kapsenberg ML, Hilkens CMU, Wierenga EA, Kalinski P. The role of antigen-presenting cells in the regulation of specific T cell responses. Curr Opinion Immunol 1998; 10:607-13.
32. Manickasingham SP, Edwards AD, Schulz O, Reis e Sousa C. The ability of murine dendritic cell subsets to direct T helper cell differentiation is dependent on microbial signals. Eur J Immunol 2003; 33:101-7.
33. de Jong EC, Vieira PL, Kalinski P et al. Microbial compounds selectively induce Th1 cell-promoting or Th2 cell-promoting dendritic cells in vitro with diverse Th cell polarizing signals. J Immunol 2002; 168:1704-9.
34. Cumberbatch M, Dearman RJ, Griffiths CEM, Kimber I. Epidermal Langerhans cell migration and sensitisation to chemical allergens. APMIS 2003; 111:797-804.
35. Constant S, Pfeiffer C, Woodard A, Pasqualini T, Bottomly K. Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells. J Exp Med 1995; 182:1591-6.
36. Brightling CE, Symon FA, Birring SS, Bradding P, Pavord ID, Wardlaw AJ. TH2 cytokine expression in bronchoalveolar lavage fluid T lymphocytes and bronchial submucosa is a feature of asthma and eosinophilic bronchitis. J Allergy Clin Immunol 2002; 110:899-905.
37. Barth H, Berg PA, Klein R. Methods for the in vitro determination of an individual disposition towards Th1- or Th2-reactivity by the application of appropriate stimulatory antigens. Clin Exp Immunol 2003; 134:78-85.
38. Lummus ZL, Alam R, Bernstein JA, Bernstein DI. Diisocyanate antigen-enhanced production of monocyte chemoattractant protein-1, IL-8, and tumor necrosis factor-alpha by peripheral mononuclear cells of workers with occupational asthma. J Allergy Clin Immunol 1998; 102:265-74.
39. Bernstein DI, Cartier A, Cote J et al. Diisocyanate antigen-stimulated monocyte chemoattractant protein-1 synthesis has greater test efficiency than specific antibodies for identification of diisocyanate asthma. Am J Respir Crit Care Med 2002; 166:445-50.