De-sulfation of MG-63 cell glycosaminoglycans delays in vitro osteogenesis, up-regulates cholesterol synthesis and disrupts cell cycle and the actin cytoskeleton

Journal of Cellular Physiology

Volumn 219, Issue 3, 2009, Pages 572-583

  Kumarasuriyar, A ^a,b   Lee, I ^c   Nurcombe, V ^d,e   Cool, S M ^d,e  

^a INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c NATIONAL UNIVERSITY HOSPITAL   (Singapore)

^d INSTITUTE OF MEDICAL BIOLOGY   (Singapore)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; BONE MORPHOGENETIC PROTEIN 2; CARBOHYDRATE BINDING PROTEIN; CHLORATE; CHOLESTEROL; FIBROBLAST GROWTH FACTOR 2; GLYCOSAMINOGLYCAN; NOGGIN; SYNDECAN 4; BMP2 PROTEIN, HUMAN; CARRIER PROTEIN; NOGGIN PROTEIN; SDC4 PROTEIN, HUMAN; SULFATE;

ACTIN FILAMENT; ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CARBOHYDRATE ANALYSIS; CELL ADHESION; CELL ASSAY; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL MIGRATION; CELL PROLIFERATION; CELL STIMULATION; CHOLESTEROL SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LONG TERM EXPOSURE; MICROARRAY ANALYSIS; OSTEOSARCOMA CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SULFATION; TRANSCRIPTION REGULATION; UPREGULATION; BIOSYNTHESIS; CELL CULTURE; CELL CYCLE; CELL MOTION; CHEMISTRY; CYTOLOGY; CYTOSKELETON; DRUG ANTAGONISM; DRUG EFFECT; MESENCHYMAL STEM CELL; METABOLISM; OSTEOBLAST; OSTEOSARCOMA; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ACTINS; BONE MORPHOGENETIC PROTEIN 2; CARRIER PROTEINS; CELL ADHESION; CELL CYCLE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CHLORATES; CHOLESTEROL; CYTOSKELETON; FIBROBLAST GROWTH FACTOR 2; GLYCOSAMINOGLYCANS; HUMANS; MESENCHYMAL STEM CELLS; OSTEOBLASTS; OSTEOGENESIS; OSTEOSARCOMA; SIGNAL TRANSDUCTION; SULFATES; SYNDECAN-4; UP-REGULATION;

EID: 64549133862     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21700     Document Type: Article

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