Beat-to-beat QT interval variability: Novel evidence for repolarization lability in ischemic and nonischemic dilated cardiomyopathy

Circulation

Volumn 96, Issue 5, 1997, Pages 1557-1565

  Berger, Ronald D ^a,b   Kasper, Edward K ^a   Baughman, Kenneth L ^a   Marban, Eduardo ^a   Calkins, Hugh ^a   Tomaselli, Gordon F ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Cardiomyopathy; Electrocardiography; Intervals; Repolarization

Indexed keywords

ADULT; ARTICLE; CARDIOMYOPATHY; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; ELECTROCARDIOGRAM; FEMALE; HEART REPOLARIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; QT INTERVAL; SUDDEN DEATH;

EID: 0030876316     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.96.5.1557     Document Type: Article

References (57)

1. CONSENSUS Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure: results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). N Engl J Med. 1987;316:1429-1435.
2. Cohn JN, Johnson G, Ziesche S, Cobb F, Francis G, Tristani F, Smith R, Dunkman WB, Loeb H, Wong M, Bhat G, Goldman S, Fletcher RD, Doherty J, Hughes V, Carson P, Cintron G, Shabetai R, Haakenson C. A comparison of enalapril with hydralazine-isosorbide dinitrate in treatment of chronic congestive heart failure: V-HeFT II. N Engl J Med. 1991;325:303-310.
3. Podrid PJ, Fogel RI, Fuchs TT. Ventricular arrhythmia in congestive heart failure. Am J Cardiol. 1992;69:82G-96G.
4. Anderson KP, Freedman RA, Mason JW. Sudden death in idiopathic dilated cardiomyopathy. Ann Intern Med. 1987;107:104-106.
5. Packer M. Sudden unexpected death in patients with congestive heart failure: a second frontier. Circulation. 1985;72:681-685.
6. Raitt MH, Dolack GL, Kudenchuk PJ, Poole JE, Jones GK, Bardy GH. What is the risk of primary ventricular fibrillation in patients with a history of only monomorphic ventricular tachycardia? Circulation. 1994;90(suppl I):I-454. Abstract.
7. Tomaselli GF, Beuckelmann DJ, Calkins HG, Berger RD, Kessler PD, Lawrence JH, Kass D, Feldman AM, Marban E. Sudden cardiac death in heart failure: the role of abnormal repolarization. Circulation. 1994;90:2534-2539.
8. Aronson RS. Characteristics of action potentials of hypertrophied myocardium from rats with renal hypertension. Circ Res. 1980;47: 443-454.
9. Gwathmey JK, Copelas L, MacKinnon R, Schoen FJ, Feldman MD, Grossman W, Morgan JP. Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure. Circ Res. 1987;61:70-76.
10. Beuckelmann DJ, Nabauer M, Erdmann E. Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure. Circulation. 1992;85:1046-1055.
11. Dinerman JL, Berger RD, Haigney MCP, Lawrence JH, Tomaselli GF, Calkins H. Dispersion of ventricular activation and recovery in patients with idiopathic dilated cardiomyopathy. Am J Cardiol. 1997;79:970-974.
12. Barr CS, Naas A, Freeman M, Lang CC, Struthers AD. QT dispersion and sudden unexpected death in chronic heart failure. Lancet. 1994;343:327-329.
13. Pye M, Quinn AC, Cobbe SM. QT interval dispersion: a non-invasive marker of susceptibility to arrhythmia in patients with sustained ventricular arrhythmias? Br Heart J. 1994;71:511-514.
14. Grimm W, Steder U, Menz V, Hoffmann J, Maisch B. QT dispersion and arrhythmic events in idiopathic dilated cardiomyopathy. Am J Cardiol. 1996;78:458-461.
15. Folland ED, Parisi AF, Moynihan PF. Assessment of left ventricular ejection fraction and volumes by real-time, two dimensional echocardiography: a comparison of cineographic and radionuclide techniques. Circulation. 1979;60:760-766.
16. Shock NW, Greulich RC, Andrews D, Arenberg D, Costa PT, Lakatta EG, Tobin JD. Normal Human Aging: The Baltimore Longitudinal Study on Aging. Bethesda, Md: NIH Publication No. 84-2450, 45-57; 1984.
17. Berger RD, Akselrod S, Gordon D, Cohen RJ. An efficient algorithm for spectral analysis of heart rate variability. IEEE Trans Biomed Eng BME. 1986;33:900-904.
18. Saul JP, Arai Y, Berger RD, Lilly LS, Colucci WS, Cohen RJ. Assessment of autonomic regulation in chronic congestive heart failure by heart rate spectral analysis. Am J Cardiol. 1988;61: 1292-1299.
19. Kay SM, Marple SL. Spectrum analysis: a modern perspective. Proc IEEE. 1981;69:1380-1419.
20. Berger RD, Saul JP, Cohen RJ. Transfer function analysis of autonomic regulation, I: the canine atrial rate response. Am J Physiol. 1989;25:H142-H152.
21. Jenkins GM, Watts DG. Spectral Analysis and Its Applications. Oakland, Calif: Holden-Day; 1968.
22. Day CP, McComb JM, Campbell RWF. QT dispersion: an indication of arrhythmia risk in patients with long QT intervals. Br Heart J. 1990;63:342-344.
23. Casolo G, Bali E, Taddei T, Amuhasi J, Gori C. Decreased spontaneous heart rate variability in congestive heart failure. Am J Cardiol. 1989;64:1162-1167.
24. Woo MA, Stevenson WG, Moser DK, Trelease RB, Harper RM. Patterns of beat-to-beat heart rate variability in advanced heart failure. Am Heart J. 1992;123:704-710.
25. Gradman A, Deedwania P, Cody R, Massie B, Packer M, Pitt B, Goldstein S, for the Captopril-Digoxin Study Group, Predictors of total mortality and sudden death in mild to moderate heart failure. J Am Coll Cardiol. 1989;14:564-570.
26. Beuckelmann DJ, Nabauer M, Erdmann E. Alterations of K+ currents in isolated human ventricular myocytes from patients with terminal heart failure. Circ Res. 1993;73:379-385.
27. Nabauer M, Beuckelmann DJ, Erdmann E. Characteristics of transient outward current in human ventricular myocytes from patients with terminal heart failure. Circ Res. 1993;73:386-394.
28. Gibbs CL, Johnson EA. Effect of changes in frequency of stimulation upon rabbit ventricular action potential. Circ Res. 1961;9: 165-170.
29. Edmands RE, Greenspan K, Fisch C. Effect of cycle length alteration upon the configuration of the canine ventricular action potential. Circ Res. 1966;19:602-610.
30. Elharrar V, Atarashi H, Surawicz B. Cycle length-dependent action potential duration in canine cardiac Purkinje fibers. Am J Physiol. 1984;247:H936-H945.
31. Franz MR, Swerdlow CD, Liem LB, Schaefer J. Cycle length dependence of human action potential duration in vivo: effects of single extrastimuli, sudden sustained rate acceleration and deceleration, and different steady state frequencies. J Clin Invest. 1988; 82:972-979.
32. Attwell D, Cohen I, Eisner DA. The effects of heart rate on the action potential of guinea-pig and human ventricular muscle. J Physiol. 1981;313:439-461.
33. Arnold L, Page J, Attwell D, Cannell M, Eisner DA. The dependence on heart rate of the human ventricular action potential duration. Cardiovasc Res. 1982;16:547-551.
34. Akselrod S, Gordon D, Ubel FA, Shannon DC, Barger AC, Cohen RJ. Power spectrum analysis of heart rate fluctuations: a quantitative probe of beat-to-beat cardiovascular control. Science. 1981; 213:220-222.
35. Pomeranz B, MaCaulay RJB, Caudill MA, Kutz I, Adam D, Gordon D, Kilborn KM, Barger AC, Shannon DC, Cohen RJ, Benson H. Assessment of autonomic function in humans by heart rate spectral analysis. Am J Physiol. 1985;248:H151-H153.
36. Rosen MR, Jeck CD, Steinberg SF. Autonomic modulation of cellular repolarization and of the electrocardiographic QT interval. J Cardiovasc Electrophysiol. 1992;3:487-499.
37. Davey PP, Bateman J, Mulligan IP, Forfar C, Barlow C, Hart G. QT interval dispersion in chronic heart failure and left ventricular hypertrophy: relation to autonomic nervous system and Holter tape abnormalities. Br Heart J. 1994;71:268-273.
38. Fei L, Goldman JH, Prasad K, Keeling PJ, Reardon K, Camm AJ, McKenna WJ. QT dispersion and RR variations on 12-lead ECGs in patients with congestive heart failure secondary to idiopathic dilated cardiomyopathy. Eur Heart J. 1996;17:258-263.
39. Statters DJ, Malik M, Ward DE, Camm AJ. QT dispersion: problems of methodology and clinical significance. J Cardiovasc Electrophysiol. 1994;5:672-685.
40. Surawicz B. Will QT dispersion play a role in clinical decision-making? J Cardiovasc Electrophysiol. 1996;7:777-784.
41. Algra A, Le Brun H, Zeelenberg C. An algorithm for computer measurement of QT intervals in the 24 hour ECG. Comput Cardiol. 1987;13:117-119.
42. Critelli G, Marciano F, Mazzarella M, Migaux ML. QT interval measurements of long-term ECG recordings: application of an automatic Holter analysis system. Comput Cardiol. 1982;8:481-484.
43. Pisani E, Pellegrini F, Ansuini G, Di Noto G, Rimatori C, Russo P. Performance evaluation of algorithms for QT interval measurements in ambulatory ECG recordings. Comput Cardiol. 1985; 11:459-462.
44. Laguna P, Thakor NV, Caminal P, Jane R, Yoon HR. New algorithm for QT interval analysis in 24-hour Holter ECG: performance and applications. Med Biol Eng Comput. 1990;28:67-73.
45. Merri M, Moss AJ, Benhorin J, Locati EH, Alberti M, Badilini F. Relation between ventricular repolarization duration and cardiac cycle length during 24-hour Holter recordings: findings in normal patients and patients with long QT syndrome. Circulation. 1992;85: 1816-1821.
46. Merri M, Alberti M, Moss AJ. Dynamic analysis of ventricular repolarization duration from 24-hour Holter recordings. IEEE Trans Biomed Eng. 1993;40:1219-1225.
47. Sarma JSM, Singh N, Schoenbaum MP, Venkataraman K, Singh BN. Circadian and power spectral changes of RR and QT intervals during treatment of patients with angina pectoris with nadolol providing evidence for differential autonomic modulation of heart rate and ventricular repolarization. Am J Cardiol. 1994;74:131-136.
48. Jackman WM, Szabo B, Friday KJ, Margolis PD, Moulton K, Wang X, Patterson E, Lazzara R. Ventricular tachyarrhythmias related to early afterdepolarizations and triggered firing: relationship to QT interval prolongation and potential therapeutic role for calcium channel blocking agents. J Cardiovasc Electrophysiol. 1990;1: 170-195.
49. Browne KF, Prystowsky E, Heger JJ, Chilson DA, Zipes DP. Prolongation of the QT interval in man during sleep. Am J Cardiol. 1983;52:55-59.
50. Bexton RS, Vallin HO, Camm AJ. Diurnal variation of the QT interval: influence of the autonomic nerve system. Br Heart J. 1986; 55:253-258.
51. Adam DR, Smith JM, Akselrod S, Nyberg S, Powell AO, Cohen RJ. Fluctuations in T-wave morphology and susceptibility to ventricular fibrillation. J Electrocardiol. 1984;17:209-218.
52. Smith JM, Clancy EA, Valeri CR, Ruskin JN, Cohen RJ. Electrical alternans and cardiac electrical instability. Circulation. 1988;77: 110-121.
53. Nearing BD, Huang AH, Verrier RL. Dynamic tracking of cardiac vulnerability by complex demodulation of the T wave. Science. 1991;252:437-440.
54. Rosenbaum DS, Jackson LE, Smith JN, Garan H, Ruskin JN, Cohen RJ. Electrical alternans and vulnerability to ventricular arrhythmias. N Engl J Med. 1994;330:235-241.
55. Josephson ME, Almendral JM, Buxton AE, Marchlinski FE. Mechanisms of ventricular tachycardia. Circulation. 1987;75(suppl III): III-41-III-47.
56. Almendral JM, Stamato NJ, Rosenthal ME, Marchlinski FE, Miller JM, Josephson ME. Resetting response patterns during sustained ventricular tachycardia: relationship to the excitable gap. Circulation. 1986;74:722-730.
57. Kuo C, Munakata K, Reddy CP, Surawicz B. Characteristics and possible mechanisms of ventricular arrhythmia dependent on the dispersion of action potential durations. Circulation. 1983;67: 1356-1367.