Electrophysiological Safety of Sertindole in Dogs with Normal and Remodeled Hearts

Journal of Pharmacology and Experimental Therapeutics

Volumn 307, Issue 2, 2003, Pages 776-784

  Thomsen, Morten B ^a   Volders, Paul G A ^a   Stengl, Milan ^a   Spätjens, Roel L H M G ^a   Beekman, Jet D M ^a   Bischoff, Ulrike ^b   Kall, Morten A ^c   Frederiksen, Kristen ^c   Matz, Jørgen ^c   Vos, Marc A ^a,d  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b GENION   (Germany)

^c H LUNDBECK A S   (Denmark)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DOFETILIDE; POTASSIUM ION; SERTINDOLE;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATRIOVENTRICULAR BLOCK; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOG; DRUG BLOOD LEVEL; DRUG SAFETY; ELECTROPHYSIOLOGY; HEART ARRHYTHMIA; HEART MUSCLE CELL; HEART VENTRICLE REMODELING; IC 50; ION CURRENT; LONG QT SYNDROME; MEMBRANE POTENTIAL; NONHUMAN; POTASSIUM CURRENT; POTASSIUM CURRENT ICAL; POTASSIUM CURRENT IHERG; POTASSIUM CURRENT IKCNE1; POTASSIUM CURRENT IKCNQ1; POTASSIUM CURRENT IKR; POTASSIUM CURRENT IKV.3; POTASSIUM CURRENT ISCN5A; PRIORITY JOURNAL; QT INTERVAL; SCHIZOPHRENIA; SUDDEN DEATH; TORSADE DES POINTES;

ACTION POTENTIALS; ANIMALS; ANTIPSYCHOTIC AGENTS; ARRHYTHMIA; DOGS; ELECTROPHYSIOLOGY; HEART; IMIDAZOLES; INDOLES; MYOCYTES, CARDIAC; PHENETHYLAMINES; SULFONAMIDES;

EID: 0142179141     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.052753     Document Type: Article

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