Rescue of Aβ1-42-induced memory impairment in day-old chick by facilitation of astrocytic oxidative metabolism: Implications for Alzheimer's disease

Journal of Neurochemistry

Volumn 109, Issue SUPPL. 1, 2009, Pages 230-236

  Gibbs, Marie E ^a   Gibbs, Zoe ^b   Hertz, Leif ^c  

^a MONASH UNIVERSITY   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Astrocytes; Astrocytic metabolic substrates; Bead discrimination learning; Beta amyloid; Glycolysis

Indexed keywords

3 HYDROXYBUTYRIC ACID; AMYLOID BETA PROTEIN; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; FATTY ACID; GLUCOSE; INSULIN; KETONE; LACTIC ACID; OCTANOIC ACID; ACETIC ACID DERIVATIVE; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); ANTIDIABETIC AGENT; KETONE BODY; OCTANOIC ACID DERIVATIVE; PEPTIDE FRAGMENT;

AEROBIC METABOLISM; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ASTROCYTE; CHICK; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME SUBSTRATE; GLUCOSE TRANSPORT; GLYCOLYSIS; LEARNING; MEMORY DISORDER; METABOLITE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; ANIMAL; ARTICLE; CHEMICALLY INDUCED DISORDER; CHICKEN; CITRIC ACID CYCLE; DISCRIMINATION LEARNING; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; NEWBORN; OXIDATION REDUCTION REACTION; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; REINFORCEMENT;

3-HYDROXYBUTYRIC ACID; ACETATES; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CHICKENS; CITRIC ACID CYCLE; DISCRIMINATION LEARNING; GLUCOSE; HYPOGLYCEMIC AGENTS; INSULIN; KETONE BODIES; LACTIC ACID; MEMORY DISORDERS; OCTANOIC ACIDS; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; REINFORCEMENT (PSYCHOLOGY);

EID: 64349120431     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.05800.x     Document Type: Conference Paper

References (50)

1. Blazquez C., Woods A., de Ceballos M. L., Carling D. Guzman M. (1999) The AMP-activated protein kinase is involved in the regulation of ketone body production by astrocytes. J. Neurochem. 73, 1674 1682.
2. Carrodeguas J. A., Rodolosse A., Garza M. V. et al. (2005) The chick embryo appears as a natural model for research in beta-amyloid precursor protein processing. Neuroscience 134, 1285 1300.
3. Chen X. Yan S. D. (2006) Mitochondrial Aβ: a potential cause of metabolic dysfunction in Alzheimer's disease. IUBMB Life 58, 686 694.
4. Clarke D. W., Boyd F. T., Kappy M. S. Raizada M. K. (1984) Insulin binds to specific receptors and stimulates 2-deoxy-D-glucose uptake in cultured glial cells from rat brain. J. Biol. Chem. 259, 11672 11675.
5. Craft S. (2007) Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment. Curr. Alzheimer Res. 4, 147 152.
6. Drzezga A., Lautenschlager N., Siebner H., Riemenschneider M., Willoch F., Minoshima S., Schwaiger M. Kurz A. (2003) Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: a PET follow-up study. Eur. J. Nucl. Med. Mol. Imaging 30, 1104 1113.
7. Dwyer D. S., Vannucci S. J. Simpson I. A. (2002) Expression, regulation, and functional role of glucose transporters (GLUTs) in brain. Int. Rev. Neurobiol. 51, 159 188.
8. 13C nuclear magnetic resonance spectroscopy. J. Neurosci. 23, 5928 5935.
9. Edmond J. (1992) Energy metabolism in developing brain cells. Can. J. Physiol. Pharmacol. 70, S118 S129.
10. Edmond J., Auestad N., Robbins R. A. Bergstrom J. D. (1985) Ketone body metabolism in the neonate: development and the effect of diet. Fed. Proc. 44, 2359 2364.
11. Gibbs M. E. (2008) Memory systems in the chick: regional and temporal control by noradrenaline. Brain Res. Bull. 76, 180 182.
12. Gibbs M. E. Ng K. T. (1977) Psychobiology of memory: towards a model of memory formation. Biobehav. Rev. 1, 113 136.
13. Gibbs M. E. Summers R. J. (2002) Role of adrenoceptor subtypes in memory consolidation. Prog. Neurobiol. 67, 345 391.
14. Gibbs M. E., O'Dowd B. S., Hertz E. Hertz L. (2006) Astrocytic energy metabolism consolidates memory in young chicks. Neuroscience 141, 9 13.
15. Gibbs M. E., Hutchinson D. S. Hertz L. (2008a) Astrocyte metabolism and function during learning. Neurosci. Biobehav. Rev. 32, 927 944.
16. 2-adrenoceptors on glycogenolysis. Neuropsychopharmacology 33, 2384 2397.
17. 3-adrenoceptor agonist. Neurobiol. Aging. doi :.
18. Guzman M. Blazquez C. (2001) Is there an astrocyte-neuron ketone body shuttle? Trends Endocrinol. Metab. 12, 169 173.
19. Haxby J. V., Grady C. L., Koss E., Horwitz B., Heston L., Schapiro M., Friedland R. P. Rapoport S. I. (1990) Longitudinal study of cerebral metabolic asymmetries and associated neuropsychological patterns in early dementia of the Alzheimer type. Arch. Neurol. 47, 753 760.
20. Hoyer S. (1998) Is sporadic Alzheimer disease the brain type of non-insulin dependent diabetes mellitus? A challenging hypothesis. J. Neural Transm. 105, 415 422.
21. Hoyer S. (2004) Glucose metabolism and insulin receptor signal transduction in Alzheimer disease. Eur. J. Pharmacol. 490, 115 125.
22. Hoyer S., Oesterreich K. Wagner O. (1988) Glucose metabolism as the site of the primary abnormality in early-onset dementia of Alzheimer type? J. Neurol. 235, 143 148.
23. Hunt A., Schonknecht P., Henze M., Seidl U., Haberkorn U. Schroder J. (2007) Reduced cerebral glucose metabolism in patients at risk for Alzheimer's disease. Psychiatry Res. 155, 147 154.
24. Hutchinson D. S., Summers R. J. Gibbs M. E. (2008) Energy metabolism and memory processing: role of glucose transport and glycogen in responses to adrenoceptor activation in the chicken. Brain Res. Bull. 76, 224 234.
25. Johnson N. A., Jahng G. H., Weiner M. W., Miller B. L., Chui H. C., Jagust W. J., Gorno-Tempini M. L. Schuff N. (2005) Pattern of cerebral hypoperfusion in Alzheimer disease and mild cognitive impairment measured with arterial spin-labeling MR imaging: initial experience. Radiology 234, 851 859.
26. Krebs D. L. Parent M. B. (2005) The enhancing effects of hippocampal infusions of glucose are not restricted to spatial working memory. Neurobiol. Learn. Mem. 83, 168 172.
27. Lambert M. P., Barlow A. K., Chromy B. A. et al. (1998) Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc. Natl Acad. Sci. USA 95, 6448 6453.
28. Lester-Coll N., Rivera E. J., Soscia S. J., Doiron K., Wands J. R. de la Monte S. M. (2006) Intracerebral streptozotocin model of type 3 diabetes: relevance to sporadic Alzheimer's disease. J. Alzheimers Dis. 9, 13 33.
29. Miles J. M., Cattalini M., Sharbrough F. W., Wold L. E., Wharen R. E. Jr., Gerich J. E. Haymond M. W. (1991) Metabolic and neurologic effects of an intravenous medium-chain triglyceride emulsion. J. Parenter. Enteral Nutr. 15, 37 41.
30. Mileusnic R., Lancashire C., Clark J. Rose S. P. (2007) Protection against Abeta-induced memory loss by tripeptide D-Arg-L-Glu-L-Arg. Behav. Pharmacol. 18, 231 238.
31. Muir D., Berl S. Clarke D. D. (1986) Acetate and fluoroacetate as possible markers for glial metabolism in vivo. Brain Res. 380, 336 340.
32. 14C-trajectography combined with immunohistochemistry. J. Cereb. Blood Flow Metab. 24, 1004 1014.
33. Plaschke K. Hoyer S. (1993) Action of the diabetogenic drug streptozotocin on glycolytic and glycogenolytic metabolism in adult rat brain cortex and hippocampus. Int. J. Dev. Neurosci. 11, 477 483.
34. Poling A., Morgan-Paisley K., Panos J. J. et al. (2008) Oligomers of the amyloid-beta protein disrupt working memory: confirmation with two behavioral procedures. Behav. Brain Res. 193, 230 234.
35. Reger M. A., Henderson S. T., Hale C., Cholerton B, Baker L. D., Watson G. S., Hyde K., Chapman D. Craft S. (2004) Effects of beta-hydroxybutyrate on cognition in memory-impaired adults. Neurobiol. Aging 25, 311 314.
36. Reiner A., Perkel D. J., Bruce L. L. et al. (2004) Revised nomenclature for avian telencephalon and some related brainstem nuclei. J. Comp. Neurol. 473, 377 414.
37. Rosenzweig M. R., Bennett E. L., Colombo P., Lee D. W. Serrano P. A. (1993) Short-term, intermediate-term, and long-term memories. Behav. Brain Res. 57, 193 198.
38. Seki Y., Sato K., Kono T., Abe H. Akiba Y. (2003) Broiler chickens (Ross strain) lack insulin-responsive glucose transporter GLUT4 and have GLUT8 cDNA. Gen. Comp. Endocrinol. 133, 80 87.
39. Slosman D. O., Ludwig C., Zerarka S. et al. (2001) Brain energy metabolism in Alzheimer's disease: 99mTc-HMPAO SPECT imaging during verbal fluency and role of astrocytes in the cellular mechanism of 99mTc-HMPAO retention. Brain Res. Rev. 36, 230 240.
40. Small B. J. Bäckman L. (2007) Longitudinal trajectories of cognitive change in preclinical Alzheimer's disease: a growth mixture modeling analysis. Cortex 43, 826 834.
41. Small D. H., Mok S. S. Bornstein J. C. (2001) Alzheimer's disease and Abeta toxicity: from top to bottom. Nat. Rev. Neurosci. 2, 595 598.
42. Spector R. (1988) Fatty acid transport through the blood-brain barrier. J. Neurochem. 50, 639 643.
43. Storey E., Kinsella G. J. Slavin M. J. (2001) The neuropsychological diagnosis of Alzheimer's disease. J. Alzheimers Dis. 3, 261 285.
44. Sun M. K. Alkon D. L. (2006) Links between Alzheimer's disease and diabetes. Drugs Today (Barc.) 42, 481 489.
45. 1-42 and glyceraldehyde phosphodehydrogenase. J. Pept. Sci. 14, 755 762.
46. Walsh D. M. Selkoe D. J. (2004) Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron 44, 181 193.
47. Waniewski R. A. Martin D. L. (1998) Preferential utilization of acetate by astrocytes is attributable to transport. J. Neurosci. 18, 5225 5233.
48. Watson G. S. Craft S. (2004) Modulation of memory by insulin and glucose: neuropsychological observations in Alzheimer's disease. Eur. J. Pharmacol. 490, 97 113.
49. Werner H., Raizada M. K., Mudd L. M., Foyt H. L., Simpson I. A., Roberts C. T. Jr. LeRoith D. (1989) Regulation of rat brain/HepG2 glucose transporter gene expression by insulin and insulin-like growth factor-I in primary cultures of neuronal and glial cells. Endocrinology 125, 314 320.
50. Zhao W. Q., De Felice F. G., Fernandez S., Chen H., Lambert M. P., Quon M. J., Krafft G. A. Klein W. L. (2008) Amyloid beta oligomers induce impairment of neuronal insulin receptors. FASEB J. 22, 246 260.