Diastereo- And enantioselective synthesis of β-Hydroxy-α-amino acids: Application to the synthesis of a key intermediate for lactacystin

Journal of Organic Chemistry

Volumn 74, Issue 4, 2009, Pages 1627-1631

  Li, Qiong ^a   Yang, Shao Bo ^a   Zhang, Zhihui ^b   Li, Lei ^a   Xu, Peng Fei ^a  

^a LANZHOU UNIVERSITY   (China)

^b EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC CONDITIONS; CHIRAL AUXILIARIES; DIASTEREO SELECTIVITIES; ENANTIO-SELECTIVE SYNTHESIS; ENANTIOMERIC EXCESS; ENOLATES; FACILE SYNTHESIS; GOOD YIELDS; LACTACYSTIN; LITHIUM CHLORIDES; NUCLEOPHILIC ADDITIONS; RECOVERY YIELDS; STEREO-SELECTIVE;

ALDEHYDES; AMINATION; AMINO ACIDS; CHLORINE COMPOUNDS; ISOMERS; ORGANIC ACIDS;

AMINES;

ALDEHYDE; ALPHA AMINO ACID; BETA HYDROXY ALPHA AMINO ACID; LACTACYSTIN; LACTONE DERIVATIVE; LITHIUM CHLORIDE; NATURAL PRODUCT; PROTEASOME INHIBITOR; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHEMICAL STRUCTURE; DIASTEREOISOMER; ENANTIOMER; ENANTIOSELECTIVITY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; STREPTOMYCES; SYNTHESIS;

ACETYLCYSTEINE; ALDEHYDES; AMINO ACIDS; HYDROLYSIS; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 64349109198     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo8023973     Document Type: Article

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