Proteomic-based detection of a protein cluster dysregulated during cardiovascular development identifies biomarkers of congenital heart defects

PLoS ONE

Volumn 4, Issue 1, 2009, Pages

  Nath, Anjali K ^a,b   Krauthammer, Michael ^b   Li, Puyao ^b   Davidov, Eugene ^a   Butler, Lucas C ^b   Copel, Joshua ^a   Katajamaa, Mikko ^c   Oresic, Matej ^c   Buhimschi, Irina ^a   Buhimschi, Catalin ^a   Snyder, Michael ^a   Madri, Joseph A ^b  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ADAM15 PROTEIN; ADAPTOR RELATED PROTEIN COMPLEX 3 BETA 1 SUBUNIT; BIOLOGICAL MARKER; CHONDROINTIN 6 SULFONTRANSFERASE; COLLAGEN TYPE 4 ALPHA 2; CXCL15 CHEMOKINE; E74 LIKE FACTOR 5; F BOX PROTEIN 42; GELATINASE A; GLUCOSE; HAIRY ENHANCE OF SPLIT 6; INSULIN; INTERLEUKIN 25; JUMONJI PROTEIN; LAMININ ALPHA4; MATRIPTASE; NOTCH1 RECEPTOR; PROPROTEIN CONVERTASE 1; PROTEIN INHIBITOR OF ACTIVATED STAT 4; PROTEIN KINASE C BINDING PROTEIN 1; PROTEIN MORCA2A; PROTEIN NOGO A; PROTEIN NOGO B; T COMPLEX EXPRESSED GENE 4; T COMPLEX PROTEIN 10; TRANSCOBALAMIN II; TRANSIENT RECEPTOR POTENTIAL CHANNEL 5; UNCLASSIFIED DRUG; WNT16 PROTEIN; ZINC FINGER PROTEIN 106; NITRIC OXIDE;

ADULT; AMNION FLUID; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DRUG SCREENING; EMBRYO; EX VIVO STUDY; FEMALE; GENE CLUSTER; HEART DEVELOPMENT; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PATHOGENESIS; PRENATAL SCREENING; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; PROTEOMICS; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING; YOLK SAC; ANIMAL; CARDIOVASCULAR SYSTEM; GENE EXPRESSION REGULATION; GENETICS; LIQUID CHROMATOGRAPHY; METABOLISM; METHODOLOGY; PREGNANCY; PRENATAL DEVELOPMENT;

ANIMALIA; MURINAE;

AMNIOTIC FLUID; ANIMALS; BIOLOGICAL MARKERS; CARDIOVASCULAR SYSTEM; CHROMATOGRAPHY, LIQUID; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUCOSE; HEART DEFECTS, CONGENITAL; HUMANS; MASS SPECTROMETRY; MICE; NITRIC OXIDE; PREGNANCY; PROTEOMICS;

EID: 64149126449     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004221     Document Type: Article

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