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Volumn 46, Issue 8-9, 2009, Pages 1824-1829

Genome-scale search of tumor-specific antigens by collective analysis of mutations, expressions and T-cell recognition

Author keywords

Cancer vaccines; Human cancer genomes; Tumor specific antigens

Indexed keywords

EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MELANOMA ANTIGEN; TUMOR ANTIGEN;

EID: 64149120251     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.01.019     Document Type: Article
Times cited : (5)

References (55)
  • 2
    • 34248550778 scopus 로고    scopus 로고
    • Targeting tumour cells with defects in the MHC Class I antigen processing pathway with CD8+ T cells specific for hydrophobic TAP- and tapasin-independent peptides: the requirement for directed access into the ER
    • Aladin F., Lautscham G., Humphries E., Coulson J., and Blake N. Targeting tumour cells with defects in the MHC Class I antigen processing pathway with CD8+ T cells specific for hydrophobic TAP- and tapasin-independent peptides: the requirement for directed access into the ER. Cancer Immunol. Immunother. 56 (2007) 1143-1152
    • (2007) Cancer Immunol. Immunother. , vol.56 , pp. 1143-1152
    • Aladin, F.1    Lautscham, G.2    Humphries, E.3    Coulson, J.4    Blake, N.5
  • 3
    • 0034068643 scopus 로고    scopus 로고
    • TAP expression provides a general method for improving the recognition of malignant cells in vivo
    • Alimonti J., Zhang Q.J., Gabathuler R., Reid G., Chen S.S., and Jefferies W.A. TAP expression provides a general method for improving the recognition of malignant cells in vivo. Nat. Biotechnol. 18 (2000) 515-520
    • (2000) Nat. Biotechnol. , vol.18 , pp. 515-520
    • Alimonti, J.1    Zhang, Q.J.2    Gabathuler, R.3    Reid, G.4    Chen, S.S.5    Jefferies, W.A.6
  • 4
    • 0347759811 scopus 로고    scopus 로고
    • Down-regulation of HLA class I antigen processing molecules: an immune escape mechanism of renal cell carcinoma?
    • Atkins D., Ferrone S., Schmahl G.E., Storkel S., and Seliger B. Down-regulation of HLA class I antigen processing molecules: an immune escape mechanism of renal cell carcinoma?. J. Urol. 171 (2004) 885-889
    • (2004) J. Urol. , vol.171 , pp. 885-889
    • Atkins, D.1    Ferrone, S.2    Schmahl, G.E.3    Storkel, S.4    Seliger, B.5
  • 6
    • 7944224384 scopus 로고    scopus 로고
    • Discovery of promiscuous HLA-II-restricted T cell epitopes with TEPITOPE
    • Bian H., and Hammer J. Discovery of promiscuous HLA-II-restricted T cell epitopes with TEPITOPE. Methods 34 (2004) 468-475
    • (2004) Methods , vol.34 , pp. 468-475
    • Bian, H.1    Hammer, J.2
  • 7
    • 33748792816 scopus 로고    scopus 로고
    • Prediction of MHC-binding peptides of flexible lengths from sequence-derived structural and physicochemical properties
    • Cui J., Han L.Y., Lin H.H., Zhang H.L., Tang Z.Q., Zheng C.J., Cao Z.W., and Chen Y.Z. Prediction of MHC-binding peptides of flexible lengths from sequence-derived structural and physicochemical properties. Mol. Immunol. 44 (2007) 866-877
    • (2007) Mol. Immunol. , vol.44 , pp. 866-877
    • Cui, J.1    Han, L.Y.2    Lin, H.H.3    Zhang, H.L.4    Tang, Z.Q.5    Zheng, C.J.6    Cao, Z.W.7    Chen, Y.Z.8
  • 8
    • 23644443226 scopus 로고    scopus 로고
    • Integrated modeling of the major events in the MHC class I antigen processing pathway
    • Donnes P., and Kohlbacher O. Integrated modeling of the major events in the MHC class I antigen processing pathway. Protein Sci. 14 (2005) 2132-2140
    • (2005) Protein Sci. , vol.14 , pp. 2132-2140
    • Donnes, P.1    Kohlbacher, O.2
  • 9
    • 2942627444 scopus 로고    scopus 로고
    • Coupling in silico and in vitro analysis of peptide-MHC binding: a bioinformatic approach enabling prediction of superbinding peptides and anchorless epitopes
    • Doytchinova I.A., Walshe V.A., Jones N.A., Gloster S.E., Borrow P., and Flower D.R. Coupling in silico and in vitro analysis of peptide-MHC binding: a bioinformatic approach enabling prediction of superbinding peptides and anchorless epitopes. J. Immunol. 172 (2004) 7495-7502
    • (2004) J. Immunol. , vol.172 , pp. 7495-7502
    • Doytchinova, I.A.1    Walshe, V.A.2    Jones, N.A.3    Gloster, S.E.4    Borrow, P.5    Flower, D.R.6
  • 10
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • Dunn G.P., Old L.J., and Schreiber R.D. The immunobiology of cancer immunosurveillance and immunoediting. Immunity 21 (2004) 137-148
    • (2004) Immunity , vol.21 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 11
    • 0036081355 scopus 로고    scopus 로고
    • Gene expression omnibus: NCBI gene expression and hybridization array data repository
    • Edgar R., Domrachev M., and Lash A.E. Gene expression omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res. 30 (2002) 207-210
    • (2002) Nucleic Acids Res. , vol.30 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 12
    • 33645825183 scopus 로고    scopus 로고
    • Thousands of samples are needed to generate a robust gene list for predicting outcome in cancer
    • Ein-Dor L., Zuk O., and Domany E. Thousands of samples are needed to generate a robust gene list for predicting outcome in cancer. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 5923-5928
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 5923-5928
    • Ein-Dor, L.1    Zuk, O.2    Domany, E.3
  • 13
    • 0034666235 scopus 로고    scopus 로고
    • Antitumor vaccination using peptide based vaccines
    • Eisenbach L., Bar-Haim E., and El-Shami K. Antitumor vaccination using peptide based vaccines. Immunol Lett. 74 (2000) 27-34
    • (2000) Immunol Lett. , vol.74 , pp. 27-34
    • Eisenbach, L.1    Bar-Haim, E.2    El-Shami, K.3
  • 14
    • 0141720783 scopus 로고    scopus 로고
    • Cancer vaccines: between the idea and the reality
    • Finn O.J. Cancer vaccines: between the idea and the reality. Nat. Rev. Immunol. 3 (2003) 630-641
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 630-641
    • Finn, O.J.1
  • 19
    • 0033120466 scopus 로고    scopus 로고
    • HLA class I antigen downregulation in human cancers: T-cell immunotherapy revives an old story
    • Hicklin D.J., Marincola F.M., and Ferrone S. HLA class I antigen downregulation in human cancers: T-cell immunotherapy revives an old story. Mol. Med. Today 5 (1999) 178-186
    • (1999) Mol. Med. Today , vol.5 , pp. 178-186
    • Hicklin, D.J.1    Marincola, F.M.2    Ferrone, S.3
  • 22
    • 0031925053 scopus 로고    scopus 로고
    • Tumour surveillance: missing peptides and MHC molecules
    • Khanna R. Tumour surveillance: missing peptides and MHC molecules. Immunol. Cell Biol. 76 (1998) 20-26
    • (1998) Immunol. Cell Biol. , vol.76 , pp. 20-26
    • Khanna, R.1
  • 23
    • 23844528191 scopus 로고    scopus 로고
    • An integrative approach to CTL epitope prediction: a combined algorithm integrating MHC class I binding, TAP transport efficiency, and proteasomal cleavage predictions
    • Larsen M.V., Lundegaard C., Lamberth K., Buus S., Brunak S., Lund O., and Nielsen M. An integrative approach to CTL epitope prediction: a combined algorithm integrating MHC class I binding, TAP transport efficiency, and proteasomal cleavage predictions. Eur. J. Immunol. 35 (2005) 2295-2303
    • (2005) Eur. J. Immunol. , vol.35 , pp. 2295-2303
    • Larsen, M.V.1    Lundegaard, C.2    Lamberth, K.3    Buus, S.4    Brunak, S.5    Lund, O.6    Nielsen, M.7
  • 26
    • 33644839506 scopus 로고    scopus 로고
    • Role of antigen-processing machinery in the in vitro resistance of squamous cell carcinoma of the head and neck cells to recognition by CTL
    • Lopez-Albaitero A., Nayak J.V., Ogino T., Machandia A., Gooding W., DeLeo A.B., Ferrone S., and Ferris R.L. Role of antigen-processing machinery in the in vitro resistance of squamous cell carcinoma of the head and neck cells to recognition by CTL. J. Immunol. 176 (2006) 3402-3409
    • (2006) J. Immunol. , vol.176 , pp. 3402-3409
    • Lopez-Albaitero, A.1    Nayak, J.V.2    Ogino, T.3    Machandia, A.4    Gooding, W.5    DeLeo, A.B.6    Ferrone, S.7    Ferris, R.L.8
  • 28
    • 0034782871 scopus 로고    scopus 로고
    • Predicting class II MHC/peptide multi-level binding with an iterative stepwise discriminant analysis meta-algorithm
    • Mallios R.R. Predicting class II MHC/peptide multi-level binding with an iterative stepwise discriminant analysis meta-algorithm. Bioinformatics 17 (2001) 942-948
    • (2001) Bioinformatics , vol.17 , pp. 942-948
    • Mallios, R.R.1
  • 29
    • 35048861923 scopus 로고    scopus 로고
    • Breast cancer vaccines: promise for the future or pipe dream?
    • Mittendorf E.A., Peoples G.E., and Singletary S.E. Breast cancer vaccines: promise for the future or pipe dream?. Cancer 110 (2007) 1677-1686
    • (2007) Cancer , vol.110 , pp. 1677-1686
    • Mittendorf, E.A.1    Peoples, G.E.2    Singletary, S.E.3
  • 31
    • 17844385106 scopus 로고    scopus 로고
    • The role of the proteasome in generating cytotoxic T-cell epitopes: insights obtained from improved predictions of proteasomal cleavage
    • Nielsen M., Lundegaard C., Lund O., and Kesmir C. The role of the proteasome in generating cytotoxic T-cell epitopes: insights obtained from improved predictions of proteasomal cleavage. Immunogenetics 57 (2005) 33-41
    • (2005) Immunogenetics , vol.57 , pp. 33-41
    • Nielsen, M.1    Lundegaard, C.2    Lund, O.3    Kesmir, C.4
  • 33
    • 0141790816 scopus 로고    scopus 로고
    • Association of tapasin and HLA class I antigen down-regulation in primary maxillary sinus squamous cell carcinoma lesions with reduced survival of patients
    • Ogino T., Bandoh N., Hayashi T., Miyokawa N., Harabuchi Y., and Ferrone S. Association of tapasin and HLA class I antigen down-regulation in primary maxillary sinus squamous cell carcinoma lesions with reduced survival of patients. Clin Cancer Res. 9 (2003) 4043-4051
    • (2003) Clin Cancer Res. , vol.9 , pp. 4043-4051
    • Ogino, T.1    Bandoh, N.2    Hayashi, T.3    Miyokawa, N.4    Harabuchi, Y.5    Ferrone, S.6
  • 35
    • 0042470540 scopus 로고    scopus 로고
    • Does the immune system see tumors as foreign or self?
    • Pardoll D. Does the immune system see tumors as foreign or self?. Annu. Rev. Immunol. 21 (2003) 807-839
    • (2003) Annu. Rev. Immunol. , vol.21 , pp. 807-839
    • Pardoll, D.1
  • 36
    • 2442705373 scopus 로고    scopus 로고
    • Random screening of proteins for HLA-A*0201-binding nine-amino acid peptides is not sufficient for identifying CD8 T cell epitopes recognized in the context of HLA-A*0201
    • Pelte C., Cherepnev G., Wang Y., Schoenemann C., Volk H.D., and Kern F. Random screening of proteins for HLA-A*0201-binding nine-amino acid peptides is not sufficient for identifying CD8 T cell epitopes recognized in the context of HLA-A*0201. J. Immunol. 172 (2004) 6783-6789
    • (2004) J. Immunol. , vol.172 , pp. 6783-6789
    • Pelte, C.1    Cherepnev, G.2    Wang, Y.3    Schoenemann, C.4    Volk, H.D.5    Kern, F.6
  • 37
    • 0041589474 scopus 로고    scopus 로고
    • Identifying MHC class I epitopes by predicting the TAP transport efficiency of epitope precursors
    • Peters B., Bulik S., Tampe R., Van Endert P.M., and Holzhutter H.G. Identifying MHC class I epitopes by predicting the TAP transport efficiency of epitope precursors. J. Immunol. 171 (2003) 1741-1749
    • (2003) J. Immunol. , vol.171 , pp. 1741-1749
    • Peters, B.1    Bulik, S.2    Tampe, R.3    Van Endert, P.M.4    Holzhutter, H.G.5
  • 38
    • 7944232767 scopus 로고    scopus 로고
    • Virtual models of the HLA class I antigen processing pathway
    • Petrovsky N., and Brusic V. Virtual models of the HLA class I antigen processing pathway. Methods 34 (2004) 429-435
    • (2004) Methods , vol.34 , pp. 429-435
    • Petrovsky, N.1    Brusic, V.2
  • 39
    • 34247891741 scopus 로고    scopus 로고
    • More than one reason to rethink the use of peptides in vaccine design
    • Purcell A.W., McCluskey J., and Rossjohn J. More than one reason to rethink the use of peptides in vaccine design. Nat. Rev. Drug Discov. 6 (2007) 404-414
    • (2007) Nat. Rev. Drug Discov. , vol.6 , pp. 404-414
    • Purcell, A.W.1    McCluskey, J.2    Rossjohn, J.3
  • 40
    • 34548677928 scopus 로고    scopus 로고
    • Comment on "The consensus coding sequences of human breast and colorectal cancers"
    • Rubin A.F., and Green P. Comment on "The consensus coding sequences of human breast and colorectal cancers". Science 317 (2007) 1500
    • (2007) Science , vol.317 , pp. 1500
    • Rubin, A.F.1    Green, P.2
  • 41
    • 0038350948 scopus 로고    scopus 로고
    • Predicting proteasomal cleavage sites: a comparison of available methods
    • Saxova P., Buus S., Brunak S., and Kesmir C. Predicting proteasomal cleavage sites: a comparison of available methods. Int. Immunol. 15 (2003) 781-787
    • (2003) Int. Immunol. , vol.15 , pp. 781-787
    • Saxova, P.1    Buus, S.2    Brunak, S.3    Kesmir, C.4
  • 42
    • 34447136106 scopus 로고    scopus 로고
    • Cancer vaccines: moving beyond current paradigms
    • Schlom J., Arlen P.M., and Gulley J.L. Cancer vaccines: moving beyond current paradigms. Clin. Cancer Res. 13 (2007) 3776-3782
    • (2007) Clin. Cancer Res. , vol.13 , pp. 3776-3782
    • Schlom, J.1    Arlen, P.M.2    Gulley, J.L.3
  • 43
    • 0038666364 scopus 로고    scopus 로고
    • Characterization of human lymphocyte antigen class I antigen-processing machinery defects in renal cell carcinoma lesions with special emphasis on transporter-associated with antigen-processing down-regulation
    • Seliger B., Atkins D., Bock M., Ritz U., Ferrone S., Huber C., and Storkel S. Characterization of human lymphocyte antigen class I antigen-processing machinery defects in renal cell carcinoma lesions with special emphasis on transporter-associated with antigen-processing down-regulation. Clin. Cancer Res. 9 (2003) 1721-1727
    • (2003) Clin. Cancer Res. , vol.9 , pp. 1721-1727
    • Seliger, B.1    Atkins, D.2    Bock, M.3    Ritz, U.4    Ferrone, S.5    Huber, C.6    Storkel, S.7
  • 44
    • 0033827817 scopus 로고    scopus 로고
    • Antigen-processing machinery breakdown and tumor growth
    • Seliger B., Maeurer M.J., and Ferrone S. Antigen-processing machinery breakdown and tumor growth. Immunol. Today 21 (2000) 455-464
    • (2000) Immunol. Today , vol.21 , pp. 455-464
    • Seliger, B.1    Maeurer, M.J.2    Ferrone, S.3
  • 45
    • 0035117550 scopus 로고    scopus 로고
    • Immunization with tumor-associated epitopes fused to an endoplasmic reticulum translocation signal sequence affords protection against tumors with down-regulated expression of MHC and peptide transporters
    • Sherritt M., Cooper L., Moss D.J., Kienzle N., Altman J., and Khanna R. Immunization with tumor-associated epitopes fused to an endoplasmic reticulum translocation signal sequence affords protection against tumors with down-regulated expression of MHC and peptide transporters. Int. Immunol. 13 (2001) 265-271
    • (2001) Int. Immunol. , vol.13 , pp. 265-271
    • Sherritt, M.1    Cooper, L.2    Moss, D.J.3    Kienzle, N.4    Altman, J.5    Khanna, R.6
  • 46
    • 0026547421 scopus 로고
    • Stroma is critical for preventing or permitting immunological destruction of antigenic cancer cells
    • Singh S., Ross S.R., Acena M., Rowley D.A., and Schreiber H. Stroma is critical for preventing or permitting immunological destruction of antigenic cancer cells. J. Exp. Med. 175 (1992) 139-146
    • (1992) J. Exp. Med. , vol.175 , pp. 139-146
    • Singh, S.1    Ross, S.R.2    Acena, M.3    Rowley, D.A.4    Schreiber, H.5
  • 51
    • 61349186956 scopus 로고    scopus 로고
    • HER-2/neu mediated down-regulation of MHC class I antigen processing prevents CTL-mediated tumor recognition upon DNA vaccination in HLA-A2 transgenic mice
    • Vertuani S., Triulzi C., Roos A.K., Charo J., Norell H., Lemonnier F., Pisa P., Seliger B., and Kiessling R. HER-2/neu mediated down-regulation of MHC class I antigen processing prevents CTL-mediated tumor recognition upon DNA vaccination in HLA-A2 transgenic mice. Cancer Immunol. Immunother. 58 (2009) 653-664
    • (2009) Cancer Immunol. Immunother. , vol.58 , pp. 653-664
    • Vertuani, S.1    Triulzi, C.2    Roos, A.K.3    Charo, J.4    Norell, H.5    Lemonnier, F.6    Pisa, P.7    Seliger, B.8    Kiessling, R.9
  • 52
    • 0030057218 scopus 로고    scopus 로고
    • T cell activation determined by T cell receptor number and tunable thresholds
    • Viola A., and Lanzavecchia A. T cell activation determined by T cell receptor number and tunable thresholds. Science 273 (1996) 104-106
    • (1996) Science , vol.273 , pp. 104-106
    • Viola, A.1    Lanzavecchia, A.2
  • 55
    • 33748987908 scopus 로고    scopus 로고
    • Cancer despite immunosurveillance: immunoselection and immunosubversion
    • Zitvogel L., Tesniere A., and Kroemer G. Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat. Rev. Immunol. 6 (2006) 715-727
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 715-727
    • Zitvogel, L.1    Tesniere, A.2    Kroemer, G.3


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