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Volumn 276, Issue 9, 2009, Pages 2599-2614

Betulinic acid-mediated inhibitory effect on hepatitis B virus by suppression of manganese superoxide dismutase expression

Author keywords

Apoptosis; CREB; Mitochondrial; Pulsatilla chinensis; Reactive oxygen species

Indexed keywords

BETULIC ACID; CASPASE 3; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOCHROME C; HEPATITIS B VIRUS X PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; SERINE;

EID: 64149101091     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.06988.x     Document Type: Article
Times cited : (53)

References (47)
  • 1
    • 0027367336 scopus 로고
    • Molecular virology and pathogenesis of hepatitis B
    • Lau JY Wright TL (1993) Molecular virology and pathogenesis of hepatitis B. Lancet 342, 1335 1340.
    • (1993) Lancet , vol.342 , pp. 1335-1340
    • Lau, J.Y.1    Wright, T.L.2
  • 2
    • 34249023734 scopus 로고    scopus 로고
    • Complementary and alternative medicine (CAM) for the treatment of chronic hepatitis B and C: A review
    • Modi AA, Wright EC Seeff LB (2007) Complementary and alternative medicine (CAM) for the treatment of chronic hepatitis B and C: a review. Antivir Ther 12, 285 295.
    • (2007) Antivir Ther , vol.12 , pp. 285-295
    • Modi, A.A.1    Wright, E.C.2    Seeff, L.B.3
  • 3
    • 4444341386 scopus 로고    scopus 로고
    • Apoptotic activity of betulinic acid derivatives on murine melanoma B16 cell line
    • Liu WK, Ho JC, Cheung FW, Liu BP, Ye WC Che CT (2004) Apoptotic activity of betulinic acid derivatives on murine melanoma B16 cell line. Eur J Pharmacol 498, 71 78.
    • (2004) Eur J Pharmacol , vol.498 , pp. 71-78
    • Liu, W.K.1    Ho, J.C.2    Cheung, F.W.3    Liu, B.P.4    Ye, W.C.5    Che, C.T.6
  • 4
    • 33846918465 scopus 로고    scopus 로고
    • Synthesis and cytotoxic activity of 17-carboxylic acid modified 23-hydroxy betulinic acid ester derivatives
    • Bi Y, Xu J, Wu X, Ye W, Yuan S Zhang L (2007) Synthesis and cytotoxic activity of 17-carboxylic acid modified 23-hydroxy betulinic acid ester derivatives. Bioorg Med Chem Lett 17, 1475 1478.
    • (2007) Bioorg Med Chem Lett , vol.17 , pp. 1475-1478
    • Bi, Y.1    Xu, J.2    Wu, X.3    Ye, W.4    Yuan, S.5    Zhang, L.6
  • 9
    • 14744293458 scopus 로고    scopus 로고
    • Betulinic acid and its derivatives: A review on their biological properties
    • Yogeeswari P Sriram D (2005) Betulinic acid and its derivatives: a review on their biological properties. Curr Med Chem 12, 657 666.
    • (2005) Curr Med Chem , vol.12 , pp. 657-666
    • Yogeeswari, P.1    Sriram, D.2
  • 11
    • 0029781555 scopus 로고    scopus 로고
    • The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice
    • Yen HC, Oberley TD, Vichitbandha S, Ho YS St Clair DK (1996) The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice. J Clin Invest 98, 1253 1260.
    • (1996) J Clin Invest , vol.98 , pp. 1253-1260
    • Yen, H.C.1    Oberley, T.D.2    Vichitbandha, S.3    Ho, Y.S.4    St Clair, D.K.5
  • 13
    • 34447527080 scopus 로고    scopus 로고
    • The role of a single-stranded nucleotide loop in transcriptional regulation of the human sod2 gene
    • Xu Y, Fang F, Dhar SK, St Clair WH, Kasarskis EJ St Clair DK (2007) The role of a single-stranded nucleotide loop in transcriptional regulation of the human sod2 gene. J Biol Chem 282, 15981 15994.
    • (2007) J Biol Chem , vol.282 , pp. 15981-15994
    • Xu, Y.1    Fang, F.2    Dhar, S.K.3    St Clair, W.H.4    Kasarskis, E.J.5    St Clair, D.K.6
  • 14
    • 0033531247 scopus 로고    scopus 로고
    • Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells
    • Xu Y, Krishnan A, Wan XS, Majima H, Yeh CC, Ludewig G, Kasarskis EJ St Clair DK (1999) Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells. Oncogene 18, 93 102.
    • (1999) Oncogene , vol.18 , pp. 93-102
    • Xu, Y.1    Krishnan, A.2    Wan, X.S.3    Majima, H.4    Yeh, C.C.5    Ludewig, G.6    Kasarskis, E.J.7    St Clair, D.K.8
  • 15
    • 34247335418 scopus 로고    scopus 로고
    • Integrated molecular profiling of SOD2 expression in multiple myeloma
    • Hurt EM, Thomas SB, Peng B Farrar WL (2007) Integrated molecular profiling of SOD2 expression in multiple myeloma. Blood 109, 3953 3962.
    • (2007) Blood , vol.109 , pp. 3953-3962
    • Hurt, E.M.1    Thomas, S.B.2    Peng, B.3    Farrar, W.L.4
  • 16
    • 0030994248 scopus 로고    scopus 로고
    • Transcriptional inhibition of manganese superoxide dismutase (SOD2) gene expression by DNA methylation of the 5′ CpG island
    • Huang Y, Peng J, Oberley LW Domann FE (1997) Transcriptional inhibition of manganese superoxide dismutase (SOD2) gene expression by DNA methylation of the 5′ CpG island. Free Radic Biol Med 23, 314 320.
    • (1997) Free Radic Biol Med , vol.23 , pp. 314-320
    • Huang, Y.1    Peng, J.2    Oberley, L.W.3    Domann, F.E.4
  • 17
    • 0037593888 scopus 로고    scopus 로고
    • Redox regulation of cAMP-responsive element-binding protein and induction of manganous superoxide dismutase in nerve growth factor-dependent cell survival
    • Bedogni B, Pani G, Colavitti R, Riccio A, Borrello S, Murphy M, Smith R, Eboli ML Galeotti T (2003) Redox regulation of cAMP-responsive element-binding protein and induction of manganous superoxide dismutase in nerve growth factor-dependent cell survival. J Biol Chem 278, 16510 16519.
    • (2003) J Biol Chem , vol.278 , pp. 16510-16519
    • Bedogni, B.1    Pani, G.2    Colavitti, R.3    Riccio, A.4    Borrello, S.5    Murphy, M.6    Smith, R.7    Eboli, M.L.8    Galeotti, T.9
  • 19
    • 0024445798 scopus 로고
    • Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
    • Gonzalez GA Montminy MR (1989) Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 59, 675 680.
    • (1989) Cell , vol.59 , pp. 675-680
    • Gonzalez, G.A.1    Montminy, M.R.2
  • 20
    • 0034234237 scopus 로고    scopus 로고
    • CBP-p300 in cell growth, transformation, and development
    • Goodman RH Smolik S (2000) CBP-p300 in cell growth, transformation, and development. Genes Dev 14, 1553 1577.
    • (2000) Genes Dev , vol.14 , pp. 1553-1577
    • Goodman, R.H.1    Smolik, S.2
  • 22
    • 0028969725 scopus 로고
    • Impaired cyclic AMP-dependent phosphorylation renders CREB a repressor of C-EBP-induced transcription of the somatostatin gene in an insulinoma cell line
    • Vallejo M, Gosse ME, Beckman W Habener JF (1995) Impaired cyclic AMP-dependent phosphorylation renders CREB a repressor of C-EBP-induced transcription of the somatostatin gene in an insulinoma cell line. Mol Cell Biol 15, 415 424.
    • (1995) Mol Cell Biol , vol.15 , pp. 415-424
    • Vallejo, M.1    Gosse, M.E.2    Beckman, W.3    Habener, J.F.4
  • 23
    • 0030463470 scopus 로고    scopus 로고
    • CREB phosphorylation and dephosphorylation: A Ca(2+)- and stimulus duration-dependent switch for hippocampal gene expression
    • Bito H, Deisseroth K Tsien RW (1996) CREB phosphorylation and dephosphorylation: a Ca(2+)- and stimulus duration-dependent switch for hippocampal gene expression. Cell 87, 1203 1214.
    • (1996) Cell , vol.87 , pp. 1203-1214
    • Bito, H.1    Deisseroth, K.2    Tsien, R.W.3
  • 25
    • 0025325391 scopus 로고
    • Negative and positive regulation by transcription factor cAMP response element-binding protein is modulated by phosphorylation
    • Lamph WW, Dwarki VJ, Ofir R, Montminy M Verma IM (1990) Negative and positive regulation by transcription factor cAMP response element-binding protein is modulated by phosphorylation. Proc Natl Acad Sci USA 87, 4320 4324.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4320-4324
    • Lamph, W.W.1    Dwarki, V.J.2    Ofir, R.3    Montminy, M.4    Verma, I.M.5
  • 26
    • 34547092456 scopus 로고    scopus 로고
    • DNA binding and phosphorylation induce conformational alterations in the kinase-inducible domain of CREB. Implications for the mechanism of transcription function
    • Sharma N, Lopez DI Nyborg JK (2007) DNA binding and phosphorylation induce conformational alterations in the kinase-inducible domain of CREB. Implications for the mechanism of transcription function. J Biol Chem 282, 19872 19883.
    • (2007) J Biol Chem , vol.282 , pp. 19872-19883
    • Sharma, N.1    Lopez, D.I.2    Nyborg, J.K.3
  • 27
    • 34447529462 scopus 로고    scopus 로고
    • Protein kinase D induces transcription through direct phosphorylation of the cAMP-response element-binding protein
    • Johannessen M, Delghandi MP, Rykx A, Dragset M, Vandenheede JR, Van Lint J Moens U (2007) Protein kinase D induces transcription through direct phosphorylation of the cAMP-response element-binding protein. J Biol Chem 282, 14777 14787.
    • (2007) J Biol Chem , vol.282 , pp. 14777-14787
    • Johannessen, M.1    Delghandi, M.P.2    Rykx, A.3    Dragset, M.4    Vandenheede, J.R.5    Van Lint, J.6    Moens, U.7
  • 29
    • 0034774463 scopus 로고    scopus 로고
    • Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress
    • Waris G, Huh KW Siddiqui A (2001) Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress. Mol Cell Biol 21, 7721 7730.
    • (2001) Mol Cell Biol , vol.21 , pp. 7721-7730
    • Waris, G.1    Huh, K.W.2    Siddiqui, A.3
  • 30
    • 33646193810 scopus 로고    scopus 로고
    • Activation of focal adhesion kinase by hepatitis B virus HBx protein: Multiple functions in viral replication
    • Bouchard MJ, Wang L Schneider RJ (2006) Activation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication. J Virol 80, 4406 4414.
    • (2006) J Virol , vol.80 , pp. 4406-4414
    • Bouchard, M.J.1    Wang, L.2    Schneider, R.J.3
  • 32
    • 0036208949 scopus 로고    scopus 로고
    • Characterization of the mitochondrial association of hepatitis B virus X protein, HBx
    • Huh KW Siddiqui A (2002) Characterization of the mitochondrial association of hepatitis B virus X protein, HBx. Mitochondrion 1, 349 359.
    • (2002) Mitochondrion , vol.1 , pp. 349-359
    • Huh, K.W.1    Siddiqui, A.2
  • 33
    • 33646114053 scopus 로고    scopus 로고
    • Hepatitis B virus X protein induces apoptosis in hepatoma cells through inhibiting Bcl-xL expression
    • Miao J, Chen GG, Chun SY Lai PP (2006) Hepatitis B virus X protein induces apoptosis in hepatoma cells through inhibiting Bcl-xL expression. Cancer Lett 236, 115 124.
    • (2006) Cancer Lett , vol.236 , pp. 115-124
    • Miao, J.1    Chen, G.G.2    Chun, S.Y.3    Lai, P.P.4
  • 34
    • 33748288087 scopus 로고    scopus 로고
    • Molecular functions and biological roles of hepatitis B virus x protein
    • Tang H, Oishi N, Kaneko S Murakami S (2006) Molecular functions and biological roles of hepatitis B virus x protein. Cancer Sci 97, 977 983.
    • (2006) Cancer Sci , vol.97 , pp. 977-983
    • Tang, H.1    Oishi, N.2    Kaneko, S.3    Murakami, S.4
  • 35
    • 33846968150 scopus 로고    scopus 로고
    • Supramolecular structure of the mitochondrial oxidative phosphorylation system
    • Boekema EJ Braun HP (2007) Supramolecular structure of the mitochondrial oxidative phosphorylation system. J Biol Chem 282, 1 4.
    • (2007) J Biol Chem , vol.282 , pp. 1-4
    • Boekema, E.J.1    Braun, H.P.2
  • 36
    • 0029130068 scopus 로고
    • High-level hepatitis B virus replication in transgenic mice
    • Guidotti LG, Matzke B, Schaller H Chisari FV (1995) High-level hepatitis B virus replication in transgenic mice. J Virol 69, 6158 6169.
    • (1995) J Virol , vol.69 , pp. 6158-6169
    • Guidotti, L.G.1    Matzke, B.2    Schaller, H.3    Chisari, F.V.4
  • 37
    • 0029148749 scopus 로고
    • Hepatitis B virus transgenic mice: Insights into the virus and the disease
    • Chisari FV (1995) Hepatitis B virus transgenic mice: insights into the virus and the disease. Hepatology 22, 1316 1325.
    • (1995) Hepatology , vol.22 , pp. 1316-1325
    • Chisari, F.V.1
  • 38
    • 34547481504 scopus 로고    scopus 로고
    • Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver
    • Patel RD, Hollingshead BD, Omiecinski CJ Perdew GH (2007) Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver. Hepatology 46, 209 218.
    • (2007) Hepatology , vol.46 , pp. 209-218
    • Patel, R.D.1    Hollingshead, B.D.2    Omiecinski, C.J.3    Perdew, G.H.4
  • 39
    • 27544495240 scopus 로고    scopus 로고
    • Fatty acid-mediated intracellular iron translocation: A synergistic mechanism of oxidative injury
    • Yao D, Shi W, Gou Y, Zhou X, Yee Aw T, Zhou Y Liu Z (2005) Fatty acid-mediated intracellular iron translocation: a synergistic mechanism of oxidative injury. Free Radic Biol Med 39, 1385 1398.
    • (2005) Free Radic Biol Med , vol.39 , pp. 1385-1398
    • Yao, D.1    Shi, W.2    Gou, Y.3    Zhou, X.4    Yee Aw, T.5    Zhou, Y.6    Liu, Z.7
  • 40
    • 0041834907 scopus 로고    scopus 로고
    • Quantitative analysis of betulinic acid in mouse, rat and dog plasma using electrospray liquid chromatography-mass spectrometry
    • Cheng X, Shin YG, Levine BS, Smith AC, Tomaszewski JE van Breemen RB (2003) Quantitative analysis of betulinic acid in mouse, rat and dog plasma using electrospray liquid chromatography-mass spectrometry. Rapid Commun Mass Spectrom 17, 2089 2092.
    • (2003) Rapid Commun Mass Spectrom , vol.17 , pp. 2089-2092
    • Cheng, X.1    Shin, Y.G.2    Levine, B.S.3    Smith, A.C.4    Tomaszewski, J.E.5    Van Breemen, R.B.6
  • 41
    • 0030892906 scopus 로고    scopus 로고
    • Inhibition of p53-mediated transactivation and cell cycle arrest by E1A through its p300-CBP-interacting region
    • Somasundaram K El-Deiry WS (1997) Inhibition of p53-mediated transactivation and cell cycle arrest by E1A through its p300-CBP-interacting region. Oncogene 14, 1047 1057.
    • (1997) Oncogene , vol.14 , pp. 1047-1057
    • Somasundaram, K.1    El-Deiry, W.S.2
  • 42
    • 2642544592 scopus 로고    scopus 로고
    • Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter
    • Metivier R, Penot G, Hubner MR, Reid G, Brand H, Kos M Gannon F (2003) Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter. Cell 115, 751 763.
    • (2003) Cell , vol.115 , pp. 751-763
    • Metivier, R.1    Penot, G.2    Hubner, M.R.3    Reid, G.4    Brand, H.5    Kos, M.6    Gannon, F.7
  • 44
    • 14144255291 scopus 로고    scopus 로고
    • Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs
    • Uprichard SL, Boyd B, Althage A Chisari FV (2005) Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs. Proc Natl Acad Sci USA 102, 773 778.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 773-778
    • Uprichard, S.L.1    Boyd, B.2    Althage, A.3    Chisari, F.V.4
  • 46
    • 0037155044 scopus 로고    scopus 로고
    • Regression of atherosclerosis in monkeys reduces vascular superoxide levels
    • Hathaway CA, Heistad DD, Piegors DJ Miller FJ Jr. (2002) Regression of atherosclerosis in monkeys reduces vascular superoxide levels. Circ Res 90, 277 283.
    • (2002) Circ Res , vol.90 , pp. 277-283
    • Hathaway, C.A.1    Heistad, D.D.2    Piegors, D.J.3    Miller, Jr.F.J.4
  • 47
    • 0344043305 scopus 로고    scopus 로고
    • Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis
    • Miller FJ Jr., Gutterman DD, Rios CD, Heistad DD Davidson BL (1998) Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis. Circ Res 82, 1298 1305.
    • (1998) Circ Res , vol.82 , pp. 1298-1305
    • Miller, Jr.F.J.1    Gutterman, D.D.2    Rios, C.D.3    Heistad, D.D.4    Davidson, B.L.5


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