Synthesis and cytotoxic activity of 17-carboxylic acid modified 23-hydroxy betulinic acid ester derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 5, 2007, Pages 1475-1478

  Bi, Yi ^a   Xu, Jinyi ^a   Wu, Xiaoming ^a   Ye, Wencai ^a   Yuan, Shengtao ^a   Zhang, Luyong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

17 Carboxylic acid modified ester derivatives; 23 Hydroxy betulinic acid; Anti tumor activity

Indexed keywords

23 HYDROXYBETULINIC ACID; 23 HYDROXYBETULINIC ACID DERIVATIVE; BETULIC ACID; CARBOXYLIC ACID DERIVATIVE; ESTER DERIVATIVE; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; LIVER TUMOR; MELANOMA; MOUSE; NONHUMAN;

ANIMALS; ANTINEOPLASTIC AGENTS; CARBOXYLIC ACIDS; CELL LINE, TUMOR; ESTERS; HUMANS; MICE; NEOPLASMS, EXPERIMENTAL; STRUCTURE-ACTIVITY RELATIONSHIP; TRITERPENES; TUMOR BURDEN;

EID: 33846918465     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.09.096     Document Type: Article

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