Transcriptional inhibition of manganese superoxide dismutase (SOD2) gene expression by DNA methylation of the 5' CpG island

Free Radical Biology and Medicine

Volumn 23, Issue 2, 1997, Pages 314-320

  Huang, Yuanhui ^a   Peng, Jiexin ^a   Oberley, Larry W ^a   Domann, Frederick E ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Antioxidant enzyme; AP 2; DNA methylation; Free radicals; Gene expression; Transcription factor; Tumor suppressor

Indexed keywords

MANGANESE SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; DNA TRANSFECTION; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; MALIGNANT NEOPLASTIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

ANIMALS; BASE SEQUENCE; BETA-GALACTOSIDASE; BINDING SITES; CHROMOSOME MAPPING; CPG ISLANDS; DNA METHYLATION; DNA, NEOPLASM; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, REPORTER; GENES, TUMOR SUPPRESSOR; HUMANS; PROMOTER REGIONS (GENETICS); RATS; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR AP-2; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0030994248     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(97)00095-6     Document Type: Article

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