Tryptophan scanning of the acetylcholine receptor's βM4 transmembrane domain: Decoding allosteric linkage at the lipid-protein interface with ion-channel gating

Channels

Volumn 2, Issue 6, 2008, Pages 439-448

  León, Rosedelma Díaz De ^a   Otero Cruz, José David ^a   Torres Nuñez, David Abner ^a   Casiano, Anette ^a   Lasalde Dominicci, José Antonio ^a  

^a UNIVERSITY OF PUERTO RICO   (Puerto Rico)

Author keywords

Acetylcholine receptor; Fourier transform; Ligand gated ion channel; Transmembrane domain; Tryptophan scanning mutagenesis

Indexed keywords

CHOLINERGIC RECEPTOR; ION CHANNEL; NICOTINIC RECEPTOR; TRYPTOPHAN; LIPID; PROTEIN;

ALLOSTERISM; AMINO ACID SUBSTITUTION; ARTICLE; CHANNEL GATING; CONFORMATIONAL TRANSITION; ELECTROPHYSIOLOGY; FOURIER ANALYSIS; FOURIER TRANSFORMATION; NONHUMAN; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; RADIOASSAY; SITE DIRECTED MUTAGENESIS; TORPEDO; WILD TYPE; XENOPUS LAEVIS; ANIMAL; BINDING SITE; GENETICS; HUMAN; METABOLISM; MOVEMENT (PHYSIOLOGY); PHYSIOLOGY; PROTEIN CONFORMATION;

ALLOSTERIC SITE; ANIMALS; ELECTROPHYSIOLOGY; HUMANS; LIPIDS; MOVEMENT; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEINS; RADIOLIGAND ASSAY; RECEPTORS, CHOLINERGIC; TRYPTOPHAN;

EID: 64149095863     PISSN: 19336950     EISSN: 19336969     Source Type: Journal    
DOI: 10.4161/chan.2.6.7130     Document Type: Article

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