-
1
-
-
0033557754
-
Adjuvanticity of the cholera toxin A1-based gene fusion protein, CTA1-DD, is critically dependent on the ADP-ribosyltransferase and Ig-binding activity
-
Agren L.C., Ekman L., Lowenadler B., Nedrud J.G., and Lycke N.Y. Adjuvanticity of the cholera toxin A1-based gene fusion protein, CTA1-DD, is critically dependent on the ADP-ribosyltransferase and Ig-binding activity. J. Immunol. 162 (1999) 2432-2440
-
(1999)
J. Immunol.
, vol.162
, pp. 2432-2440
-
-
Agren, L.C.1
Ekman, L.2
Lowenadler, B.3
Nedrud, J.G.4
Lycke, N.Y.5
-
2
-
-
0030767656
-
Selection and identification of single domain antibody fragments from camel heavy-chain antibodies
-
Arbabi Ghahroudi M., Desmyter A., Wyns L., Hamers R., and Muyldermans S. Selection and identification of single domain antibody fragments from camel heavy-chain antibodies. FEBS Lett. 414 (1997) 521-526
-
(1997)
FEBS Lett.
, vol.414
, pp. 521-526
-
-
Arbabi Ghahroudi, M.1
Desmyter, A.2
Wyns, L.3
Hamers, R.4
Muyldermans, S.5
-
3
-
-
0037218655
-
Chimeras of labile toxin one and cholera toxin retain mucosal adjuvanticity and direct Th cell subsets via their B subunit
-
Boyaka P.N., Ohmura M., Fujihashi K., Koga T., Yamamoto M., Kweon M.N., Takeda Y., Jackson R.J., Kiyono H., Yuki Y., and McGhee J.R. Chimeras of labile toxin one and cholera toxin retain mucosal adjuvanticity and direct Th cell subsets via their B subunit. J. Immunol. 170 (2003) 454-462
-
(2003)
J. Immunol.
, vol.170
, pp. 454-462
-
-
Boyaka, P.N.1
Ohmura, M.2
Fujihashi, K.3
Koga, T.4
Yamamoto, M.5
Kweon, M.N.6
Takeda, Y.7
Jackson, R.J.8
Kiyono, H.9
Yuki, Y.10
McGhee, J.R.11
-
4
-
-
0030250670
-
Affinity improvement of single antibody VH domains: residues in all three hypervariable regions affect antigen binding
-
Davies J., and Riechmann L. Affinity improvement of single antibody VH domains: residues in all three hypervariable regions affect antigen binding. Immunotechnology 2 (1996) 169-179
-
(1996)
Immunotechnology
, vol.2
, pp. 169-179
-
-
Davies, J.1
Riechmann, L.2
-
5
-
-
11144241270
-
Chemical basis for the affinity maturation of a camel single domain antibody
-
De Genst E., Handelberg F., Van Meirhaeghe A., Vynck S., Loris R., Wyns L., and Muyldermans S. Chemical basis for the affinity maturation of a camel single domain antibody. J. Biol. Chem. 279 (2004) 53593-53601
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 53593-53601
-
-
De Genst, E.1
Handelberg, F.2
Van Meirhaeghe, A.3
Vynck, S.4
Loris, R.5
Wyns, L.6
Muyldermans, S.7
-
6
-
-
0028985871
-
Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity
-
Dickinson B.L., and Clements J.D. Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity. Infect. Immun. 63 (1995) 1617-1623
-
(1995)
Infect. Immun.
, vol.63
, pp. 1617-1623
-
-
Dickinson, B.L.1
Clements, J.D.2
-
7
-
-
0030940814
-
Intranasal immunogenicity and adjuvanticity of site-directed mutant derivatives of cholera toxin
-
Douce G., Fontana M., Pizza M., Rappuoli R., and Dougan G. Intranasal immunogenicity and adjuvanticity of site-directed mutant derivatives of cholera toxin. Infect. Immun. 65 (1997) 2821-2828
-
(1997)
Infect. Immun.
, vol.65
, pp. 2821-2828
-
-
Douce, G.1
Fontana, M.2
Pizza, M.3
Rappuoli, R.4
Dougan, G.5
-
8
-
-
1842787056
-
Characterizing high-affinity antigen/antibody complexes by kinetic- and equilibrium-based methods
-
Drake A.W., Myszka D.G., and Klakamp S.L. Characterizing high-affinity antigen/antibody complexes by kinetic- and equilibrium-based methods. Anal. Biochem. 328 (2004) 35-43
-
(2004)
Anal. Biochem.
, vol.328
, pp. 35-43
-
-
Drake, A.W.1
Myszka, D.G.2
Klakamp, S.L.3
-
9
-
-
0036182644
-
Single-domain antibody fragments with high conformational stability
-
Dumoulin M., Conrath K., Van Meirhaeghe A., Meersman F., Heremans K., Frenken L.G., Muyldermans S., Wyns L., and Matagne A. Single-domain antibody fragments with high conformational stability. Protein Sci. 11 (2002) 500-515
-
(2002)
Protein Sci.
, vol.11
, pp. 500-515
-
-
Dumoulin, M.1
Conrath, K.2
Van Meirhaeghe, A.3
Meersman, F.4
Heremans, K.5
Frenken, L.G.6
Muyldermans, S.7
Wyns, L.8
Matagne, A.9
-
10
-
-
0037378940
-
Cholera toxin and its B subunit promote dendritic cell vaccination with different influences on Th1 and Th2 development
-
Eriksson K., Fredriksson M., Nordstrom I., and Holmgren J. Cholera toxin and its B subunit promote dendritic cell vaccination with different influences on Th1 and Th2 development. Infect. Immun. 71 (2003) 1740-1747
-
(2003)
Infect. Immun.
, vol.71
, pp. 1740-1747
-
-
Eriksson, K.1
Fredriksson, M.2
Nordstrom, I.3
Holmgren, J.4
-
11
-
-
0032489830
-
Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity
-
Giuliani M.M., Del Giudice G., Giannelli V., Dougan G., Douce G., Rappuoli R., and Pizza M. Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity. J. Exp. Med. 187 (1998) 1123-1132
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1123-1132
-
-
Giuliani, M.M.1
Del Giudice, G.2
Giannelli, V.3
Dougan, G.4
Douce, G.5
Rappuoli, R.6
Pizza, M.7
-
12
-
-
28244463329
-
Induction and recall of immune memory by mucosal immunization with a non-toxic recombinant enterotoxin-based chimeric protein
-
Gockel C.M., and Russell M.W. Induction and recall of immune memory by mucosal immunization with a non-toxic recombinant enterotoxin-based chimeric protein. Immunology 116 (2005) 477-486
-
(2005)
Immunology
, vol.116
, pp. 477-486
-
-
Gockel, C.M.1
Russell, M.W.2
-
13
-
-
0028962371
-
A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks
-
Greenberg A.S., Avila D., Hughes M., Hughes A., McKinney E.C., and Flajnik M.F. A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks. Nature 374 (1995) 168-173
-
(1995)
Nature
, vol.374
, pp. 168-173
-
-
Greenberg, A.S.1
Avila, D.2
Hughes, M.3
Hughes, A.4
McKinney, E.C.5
Flajnik, M.F.6
-
14
-
-
0032078331
-
Systemic immunization with urease protects mice against Helicobacter pylori infection
-
Guy B., Hessler C., Fourage S., Haensler J., Vialon-Lafay E., Rokbi B., and Millet M.J. Systemic immunization with urease protects mice against Helicobacter pylori infection. Vaccine 16 (1998) 850-856
-
(1998)
Vaccine
, vol.16
, pp. 850-856
-
-
Guy, B.1
Hessler, C.2
Fourage, S.3
Haensler, J.4
Vialon-Lafay, E.5
Rokbi, B.6
Millet, M.J.7
-
15
-
-
0035815512
-
Nasal or intramuscular immunization of mice with influenza subunit antigen and the B subunit of Escherichia coli heat-labile toxin induces IgA- or IgG-mediated protective mucosal immunity
-
Haan L., Verweij W.R., Holtrop M., Brands R., van Scharrenburg G.J., Palache A.M., Agsteribbe E., and Wilschut J. Nasal or intramuscular immunization of mice with influenza subunit antigen and the B subunit of Escherichia coli heat-labile toxin induces IgA- or IgG-mediated protective mucosal immunity. Vaccine 19 (2001) 2898-2907
-
(2001)
Vaccine
, vol.19
, pp. 2898-2907
-
-
Haan, L.1
Verweij, W.R.2
Holtrop, M.3
Brands, R.4
van Scharrenburg, G.J.5
Palache, A.M.6
Agsteribbe, E.7
Wilschut, J.8
-
16
-
-
0027310612
-
Naturally occurring antibodies devoid of light chains
-
Hamers-Casterman C., Atarhouch T., Muyldermans S., Robinson G., Hamers C., Songa E.B., Bendahman N., and Hamers R. Naturally occurring antibodies devoid of light chains. Nature 363 (1993) 446-448
-
(1993)
Nature
, vol.363
, pp. 446-448
-
-
Hamers-Casterman, C.1
Atarhouch, T.2
Muyldermans, S.3
Robinson, G.4
Hamers, C.5
Songa, E.B.6
Bendahman, N.7
Hamers, R.8
-
17
-
-
23944432459
-
Heteropentameric cholera toxin B subunit chimeric molecules genetically fused to a vaccine antigen induce systemic and mucosal immune responses: a potential new strategy to target recombinant vaccine antigens to mucosal immune systems
-
Harakuni T., Sugawa H., Komesu A., Tadano M., and Arakawa T. Heteropentameric cholera toxin B subunit chimeric molecules genetically fused to a vaccine antigen induce systemic and mucosal immune responses: a potential new strategy to target recombinant vaccine antigens to mucosal immune systems. Infect. Immun. 73 (2005) 5654-5665
-
(2005)
Infect. Immun.
, vol.73
, pp. 5654-5665
-
-
Harakuni, T.1
Sugawa, H.2
Komesu, A.3
Tadano, M.4
Arakawa, T.5
-
18
-
-
17644371966
-
Mucosal immunity and vaccines
-
Holmgren J., and Czerkinsky C. Mucosal immunity and vaccines. Nat. Med. 11 (2005) S45-53
-
(2005)
Nat. Med.
, vol.11
-
-
Holmgren, J.1
Czerkinsky, C.2
-
19
-
-
0038325751
-
Mucosal immunisation and adjuvants: a brief overview of recent advances and challenges
-
Holmgren J., Czerkinsky C., Eriksson K., and Mharandi A. Mucosal immunisation and adjuvants: a brief overview of recent advances and challenges. Vaccine 21 Suppl. 2 (2003) S89-S95
-
(2003)
Vaccine
, vol.21
, Issue.SUPPL. 2
-
-
Holmgren, J.1
Czerkinsky, C.2
Eriksson, K.3
Mharandi, A.4
-
20
-
-
4444381770
-
Intranasal immunization with inactivated influenza virus enhances immune responses to coadministered simian-human immunodeficiency virus-like particle antigens
-
Kang S.M., Guo L., Yao Q., Skountzou I., and Compans R.W. Intranasal immunization with inactivated influenza virus enhances immune responses to coadministered simian-human immunodeficiency virus-like particle antigens. J. Virol. 78 (2004) 9624-9632
-
(2004)
J. Virol.
, vol.78
, pp. 9624-9632
-
-
Kang, S.M.1
Guo, L.2
Yao, Q.3
Skountzou, I.4
Compans, R.W.5
-
21
-
-
0242643724
-
Cholera toxin activates dendritic cells through dependence on GM1-ganglioside which is mediated by NF-kappaB translocation
-
Kawamura Y.I., Kawashima R., Shirai Y., Kato R., Hamabata T., Yamamoto M., Furukawa K., Fujihashi K., McGhee J.R., Hayashi H., and Dohi T. Cholera toxin activates dendritic cells through dependence on GM1-ganglioside which is mediated by NF-kappaB translocation. Eur. J. Immunol. 33 (2003) 3205-3212
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 3205-3212
-
-
Kawamura, Y.I.1
Kawashima, R.2
Shirai, Y.3
Kato, R.4
Hamabata, T.5
Yamamoto, M.6
Furukawa, K.7
Fujihashi, K.8
McGhee, J.R.9
Hayashi, H.10
Dohi, T.11
-
22
-
-
0037449498
-
A mucosally administered recombinant fusion protein vaccine against schistosomiasis protecting against immunopathology and infection
-
Lebens M., Sun J.B., Sadeghi H., Backstrom M., Olsson I., Mielcarek N., Li B.L., Capron A., Czerkinsky C., and Holmgren J. A mucosally administered recombinant fusion protein vaccine against schistosomiasis protecting against immunopathology and infection. Vaccine 21 (2003) 514-520
-
(2003)
Vaccine
, vol.21
, pp. 514-520
-
-
Lebens, M.1
Sun, J.B.2
Sadeghi, H.3
Backstrom, M.4
Olsson, I.5
Mielcarek, N.6
Li, B.L.7
Capron, A.8
Czerkinsky, C.9
Holmgren, J.10
-
23
-
-
33646872613
-
Humoral immune responses by prime-boost heterologous route immunizations with CTB-MPR (649-684), a mucosal subunit HIV/AIDS vaccine candidate
-
Matoba N., Geyer B.C., Kilbourne J., Alfsen A., Bomsel M., and Mor T.S. Humoral immune responses by prime-boost heterologous route immunizations with CTB-MPR (649-684), a mucosal subunit HIV/AIDS vaccine candidate. Vaccine 24 (2006) 5047-5055
-
(2006)
Vaccine
, vol.24
, pp. 5047-5055
-
-
Matoba, N.1
Geyer, B.C.2
Kilbourne, J.3
Alfsen, A.4
Bomsel, M.5
Mor, T.S.6
-
24
-
-
0032876565
-
CpG DNA as mucosal adjuvant
-
McCluskie M.J., and Davis H.L. CpG DNA as mucosal adjuvant. Vaccine 18 (1999) 231-237
-
(1999)
Vaccine
, vol.18
, pp. 231-237
-
-
McCluskie, M.J.1
Davis, H.L.2
-
25
-
-
36549047962
-
Mucosal and systemic immune responses by intranasal immunization using archaeal lipid-adjuvanted vaccines
-
Patel G.B., Zhou H., Ponce A., and Chen W. Mucosal and systemic immune responses by intranasal immunization using archaeal lipid-adjuvanted vaccines. Vaccine 25 (2007) 8622-8636
-
(2007)
Vaccine
, vol.25
, pp. 8622-8636
-
-
Patel, G.B.1
Zhou, H.2
Ponce, A.3
Chen, W.4
-
26
-
-
0017150903
-
Differential expression of cell surface binding sites for cholera toxin in acute and chronic leukaemias
-
Revesz T., Greaves M.F., Capellaro D., and Murray R.K. Differential expression of cell surface binding sites for cholera toxin in acute and chronic leukaemias. Br. J. Haematol. 34 (1976) 623-630
-
(1976)
Br. J. Haematol.
, vol.34
, pp. 623-630
-
-
Revesz, T.1
Greaves, M.F.2
Capellaro, D.3
Murray, R.K.4
-
28
-
-
0037223094
-
HIV mucosal vaccine: nasal immunization with gp160-encapsulated hemagglutinating virus of Japan-liposome induces antigen-specific CTLs and neutralizing antibody responses
-
Sakaue G., Hiroi T., Nakagawa Y., Someya K., Iwatani K., Sawa Y., Takahashi H., Honda M., Kunisawa J., and Kiyono H. HIV mucosal vaccine: nasal immunization with gp160-encapsulated hemagglutinating virus of Japan-liposome induces antigen-specific CTLs and neutralizing antibody responses. J. Immunol. 170 (2003) 495-502
-
(2003)
J. Immunol.
, vol.170
, pp. 495-502
-
-
Sakaue, G.1
Hiroi, T.2
Nakagawa, Y.3
Someya, K.4
Iwatani, K.5
Sawa, Y.6
Takahashi, H.7
Honda, M.8
Kunisawa, J.9
Kiyono, H.10
-
29
-
-
0037449103
-
Stimulation of long-lasting protection against Streptococcus pyogenes after intranasal vaccination with non adjuvanted fibronectin-binding domain of the SfbI protein
-
Schulze K., Medina E., Chhatwal G.S., and Guzman C.A. Stimulation of long-lasting protection against Streptococcus pyogenes after intranasal vaccination with non adjuvanted fibronectin-binding domain of the SfbI protein. Vaccine 21 (2003) 1958-1964
-
(2003)
Vaccine
, vol.21
, pp. 1958-1964
-
-
Schulze, K.1
Medina, E.2
Chhatwal, G.S.3
Guzman, C.A.4
-
30
-
-
33846238190
-
A novel pentamer versus pentamer approach to generating neutralizers of verotoxin 1
-
Stone E., Hirama T., Chen W., Soltyk A.L., Brunton J., MacKenzie C.R., and Zhang J. A novel pentamer versus pentamer approach to generating neutralizers of verotoxin 1. Mol. Immunol. 44 (2007) 2487-2491
-
(2007)
Mol. Immunol.
, vol.44
, pp. 2487-2491
-
-
Stone, E.1
Hirama, T.2
Chen, W.3
Soltyk, A.L.4
Brunton, J.5
MacKenzie, C.R.6
Zhang, J.7
-
31
-
-
33845886914
-
The assembly of single domain antibodies into bispecific decavalent molecules
-
Stone E., Hirama T., Tanha J., Tong-Sevinc H., Li S., MacKenzie C.R., and Zhang J. The assembly of single domain antibodies into bispecific decavalent molecules. J. Immunol. Methods 318 (2007) 88-94
-
(2007)
J. Immunol. Methods
, vol.318
, pp. 88-94
-
-
Stone, E.1
Hirama, T.2
Tanha, J.3
Tong-Sevinc, H.4
Li, S.5
MacKenzie, C.R.6
Zhang, J.7
-
32
-
-
0642342122
-
Phage display technology for identifying specific antigens on brain endothelial cells
-
Tanha J., Muruganandam A., and Stanimirovic D. Phage display technology for identifying specific antigens on brain endothelial cells. Methods Mol. Med. 89 (2003) 435-449
-
(2003)
Methods Mol. Med.
, vol.89
, pp. 435-449
-
-
Tanha, J.1
Muruganandam, A.2
Stanimirovic, D.3
-
33
-
-
0031019336
-
Relationship between a low toxicity of the mutant A subunit of enterotoxigenic Escherichia coli enterotoxin and its strong adjuvant action
-
Tsuji T., Yokochi T., Kamiya H., Kawamoto Y., Miyama A., and Asano Y. Relationship between a low toxicity of the mutant A subunit of enterotoxigenic Escherichia coli enterotoxin and its strong adjuvant action. Immunology 90 (1997) 176-182
-
(1997)
Immunology
, vol.90
, pp. 176-182
-
-
Tsuji, T.1
Yokochi, T.2
Kamiya, H.3
Kawamoto, Y.4
Miyama, A.5
Asano, Y.6
-
34
-
-
0018075438
-
Mechanism of action of choleragen
-
Vaughan M., and Moss J. Mechanism of action of choleragen. J. Supramol. Struct. 8 (1978) 473-488
-
(1978)
J. Supramol. Struct.
, vol.8
, pp. 473-488
-
-
Vaughan, M.1
Moss, J.2
-
35
-
-
0027257098
-
Mucosal immunization with a subunit respiratory syncytial virus vaccine in mice
-
Walsh E.E. Mucosal immunization with a subunit respiratory syncytial virus vaccine in mice. Vaccine 11 (1993) 1135-1138
-
(1993)
Vaccine
, vol.11
, pp. 1135-1138
-
-
Walsh, E.E.1
-
36
-
-
0030902280
-
Mutants in the ADP-ribosyltransferase cleft of cholera toxin lack diarrheagenicity but retain adjuvanticity
-
Yamamoto S., Takeda Y., Yamamoto M., Kurazono H., Imaoka K., Yamamoto M., Fujihashi K., Noda M., Kiyono H., and McGhee J.R. Mutants in the ADP-ribosyltransferase cleft of cholera toxin lack diarrheagenicity but retain adjuvanticity. J. Exp. Med. 185 (1997) 1203-1210
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1203-1210
-
-
Yamamoto, S.1
Takeda, Y.2
Yamamoto, M.3
Kurazono, H.4
Imaoka, K.5
Yamamoto, M.6
Fujihashi, K.7
Noda, M.8
Kiyono, H.9
McGhee, J.R.10
-
37
-
-
4143139848
-
A pentavalent single-domain antibody approach to tumor antigen discovery and the development of novel proteomics reagents
-
Zhang J., Li Q., Nguyen T.D., Tremblay T.L., Stone E., To R., Kelly J., and Roger MacKenzie C. A pentavalent single-domain antibody approach to tumor antigen discovery and the development of novel proteomics reagents. J. Mol. Biol. 341 (2004) 161-169
-
(2004)
J. Mol. Biol.
, vol.341
, pp. 161-169
-
-
Zhang, J.1
Li, Q.2
Nguyen, T.D.3
Tremblay, T.L.4
Stone, E.5
To, R.6
Kelly, J.7
Roger MacKenzie, C.8
-
38
-
-
0344255688
-
Pentamerization of single-domain antibodies from phage libraries: a novel strategy for the rapid generation of high-avidity antibody reagents
-
Zhang J., Tanha J., Hirama T., Khieu N.H., To R., Tong-Sevinc H., Stone E., Brisson J.R., and MacKenzie C.R. Pentamerization of single-domain antibodies from phage libraries: a novel strategy for the rapid generation of high-avidity antibody reagents. J. Mol. Biol. 335 (2004) 49-56
-
(2004)
J. Mol. Biol.
, vol.335
, pp. 49-56
-
-
Zhang, J.1
Tanha, J.2
Hirama, T.3
Khieu, N.H.4
To, R.5
Tong-Sevinc, H.6
Stone, E.7
Brisson, J.R.8
MacKenzie, C.R.9
|