Copper chelator ATN-224 inhibits endothelial function by multiple mechanisms

Microvascular Research

Volumn 77, Issue 3, 2009, Pages 314-326

  Lowndes, Sarah A ^a   Sheldon, Helen V ^a   Cai, Shijie ^b   Taylor, Jennifer M ^b   Harris, Adrian L ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Angiogenesis; AQP1; ATN 224; Copper chelation; HO 1; SOD1

Indexed keywords

ANGIOPOIETIN 2; AQUAPORIN 1; ATN 224; BETA4 INTEGRIN; CASPASE 3; CASPASE 7; CHELATING AGENT; CHEMOKINE RECEPTOR CXCR4; CHOLINE TETRATHIOMOLYBDATE; COPPER; COPPER CHELATOR; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE REDUCTASE; HEME OXYGENASE 1; JAGGED1; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 2; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN ENDOPEROXIDE SYNTHASE 2; PROSTAGLANDIN SYNTHASE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P21; RECEPTOR FOR HYALURONAN MEDIATED CELL MOTILITY; SUPEROXIDE; TRANSCRIPTION FACTOR NRF1; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG POTENCY; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; QUANTITATIVE ANALYSIS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UPREGULATION;

CHELATING AGENTS; CHELATION THERAPY; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GENE SILENCING; HEME OXYGENASE-1; HUMANS; MICROARRAY ANALYSIS; MOLYBDENUM; NEOVASCULARIZATION, PHYSIOLOGIC; PERICYTES; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SUPEROXIDE DISMUTASE; TRANSFECTION; UP-REGULATION;

ANIMALIA;

EID: 64049085028     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2009.01.003     Document Type: Article

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