Cu/Zn superoxide dismutase plays a role in angiogenesis

International Journal of Cancer

Volumn 97, Issue 1, 2002, Pages 34-41

  Samant, Rajeev S ^a   Debies, Michael T ^a   Shevde, Lalita A ^a   Verderame, Michael F ^b   Welch, Danny R ^a  

^a PENN STATE CANCER INSTITUTE   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Cu Zn superoxide dismutase; Disulfiram; Endothelial; Reactive oxygen species; Transgeric mice

Indexed keywords

ANTIOXIDANT; BASIC FIBROBLAST GROWTH FACTOR; COPPER ZINC SUPEROXIDE DISMUTASE; DISULFIRAM; GLUTATHIONE; HYDROGEN PEROXIDE; OXYGEN RADICAL; REACTIVE OXYGEN METABOLITE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL METABOLISM; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; ENDOTHELIUM CELL; ENZYME ACTIVITY; GLIOMA; LEWIS CARCINOMA; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; BRAIN NEOPLASMS; CARCINOMA, LEWIS LUNG; DISULFIRAM; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GLIOMA; GLUTATHIONE; HUMANS; HYDROGEN PEROXIDE; IN SITU NICK-END LABELING; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, NUDE; MICE, TRANSGENIC; NEOVASCULARIZATION, PATHOLOGIC; RATS; SUPEROXIDE DISMUTASE; TUMOR CELLS, CULTURED;

EID: 0036132060     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.1565     Document Type: Article

References (69)

1. Angiogenic factors
2. What is the evidence that tumors are angiogenesis dependent?
3. Angiogenesis in cancer, vascular, rheumatoid and other disease
4. Blood vessel formation: What is its molecular basis?
5. Angiogenesis and metastasis
6. Molecular determinants of angiogenesis in cancer metastasis
7. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
8. Generation of superoxide anion by brain endothelial cell xanthine oxidase
9. Bovine aortic endothelial cells release hydrogen peroxide
10. The primary localization of free radical generation after anoxia/reoxygenation in isolated endothelial cells
11. Measurement of endothelial cell free radical generation: Evidence for a central mechanism of free radical injury in postischemic tissues
12. Hypoxia/reoxygenation increases the permeability of endothelial cell monolayers: Role of oxygen radicals
13. Reoxygenation of endothelial cells increases permeability by oxidant-dependent mechanisms
14. Determination of the mechanism of free radical generation in human aortic endothelial cells exposed to anoxia and reoxygenation
15. Measurement and characterization of free radical generation in reoxygenated human endothelial cells
16. - efflux which injures endothelial cells by an extracellular mechanism
17. Increased superoxide anion release from human endothelial cells in response to cytokines
18. Enzymology of oxygen
19. Oxygen-derived free radicals in postischemic tissue injury
20. Evidence that free radicals are involved in graft failure following orthotopic liver transplantation in the rat - An electron paramagnetic resonance spin trapping study
21. The biology of oxygen radicals
22. Superoxide dismutase as a target for the selective killing of cancer cells
23. The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumor growth
24. Disulfiram (tetraethylthioperoxydicarbonic diamide): A reappraisal of its toxicity and therapeutic application
25. Mechanism for the potentiation of oxygen toxicity by disulfiram
26. Inhibition of copper/zinc superoxide dismutase impairs NO -mediated endothelium-dependent relaxations
27. Seminars in medicine of the Beth Israel Hospital. Boston. Clinical applications of research on angiogenesis
28. MHC imbalance and metastatic spread in Lewis lung carcinoma clones
29. Regression of established murine carcinoma metastases following vaccination with tumour-associated antigen peptides
30. Appearance of heparinbinding EGF-like growth factor in wound fluid as a response to injury
31. Intercellular communication between vascular smooth muscle and endothelial cells mediated by HB-EGF and VEGF
32. Stimulation of tumor growth by wound-derived growth factors
33. ErbB-3 mediates differential mitogenic effects of NDF/heregulin isoforms on mouse keratinocytes
34. Wound fluid-derived heparin-binding EGF-like growth factor (HB-EGF) is synergistic with insulin-like growth factor-I for Balb/MK keratinocyte proliferation
35. Impaired neurotransmitter uptake in PC12 cells overexpressing human Cu/Zn-superoxide dismutase-implication for gene dosage effects in Down syndrome
36. Transgenic mice with increased Cu/Zn-superoxide dismutase activity: Animal model of dosage effects in Down syndrome
37. Down syndrome: Abnormal neuromuscular junction in tongue of transgenic mice with elevated levels of human Cu/Zn-superoxide dismutase
38. Lectin histochemistry of mammalian endothelium
39. Distribution of TNF alpha-like proteins correlates with some regions of programmed cell death in the chick embryo
40. Overproduction of human Cu/Zn-superoxide dismutase in transfected cells: Extenuation of paraquat-mediated cytotoxicity and enhancement of lipid peroxidation
41. A specific, sensitive and rapid method for the determination of glutathione and its application in ocular tissues
42. 2 in cultured endothelial cells
43. Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
44. Cell cycle inhibition preserves endothelial function in genetically engineered rabbit vein grafts
45. Endothelial cells: A source and target of oxidant damage
46. Induction of apoptotic cell death in human endothelial cells treated with snake venom: Implication of intracellular reactive oxygen species and protective effects of glutathione and superoxide dismutases
47. Melatonin protects bovine cerebral endothelial cells from hyperoxia-induced DNA damage and death
48. Significance of xanthine oxidase in capillary endothelial cells
49. Hypoxia injures endothelial cells by increasing endogenous xanthine oxidase activity
50. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
51. Upregulation of superoxide dismutase and nitric oxide synthase mediates the apoptosis-suppressive effects of shear stress on endothelial cells
52. Ceruloplasmin, copper ions and angiogenesis
53. Angiogenic factors and their assay: Activity of formyl methionyl leucyl phenylalanine, adenosine diphosphate, heparin, copper and bovine endothelium stimulating factor
54. Role of prostaglandin E1 and copper in angiogenesis
55. Considerations on the mechanism of the angiogenic response
56. Anticopper treatment inhibits pseudopodial protrusion and the invasive spread of 9L gliosarcoma cells in the rat brain
57. Inhibition of angiogenesis and tumor growth in the brain. Suppression of endothelial cell turnover by penicillamine and the depletion of copper, an angiogenic cofactor
58. Copper chelation inhibits tumor angiogenesis in the experimental 9L gliosarcoma model
59. Treatment of metastatic cancer with tetrathiomolybdate, an anticopper, antiangiogenic agent: Phase I study
60. Inhibition of N-n-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder cancer in rats by administration of disulfiram in the diet
61. The effect of disulfiram on the carcinogenicity of N-butyl-N-(3-carboxypropyl)nitrosamine in the rat
62. Inhibition of azoxymethane-induced intestinal cancer by disulfiram
63. Inhibition of 1,2-dimethylhydrazine-induced neoplasia of the large intestine in female CF1 mice by carbon disulfide
64. Inhibition of macromolecular binding of benzo(a)pyrene and inhibition of neoplasia by disulfiram in the mouse forestomach
65. Investigations into the metabolism and mode of action of the colon carcinogens 1,2-dimethylhydrazine and azoxymethane
66. Inhibitory effect of disulfiram on rat mammary tumor induction by N-2-fluorenylacetamide and on its metabolic conversion to N-hydroxy-N-2-fluorenylacetamide
67. Effect of exogenous glutathione on tumor progression in the murine skin multistage carcinogenesis model
68. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
69. Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells