Copper binding by tetrathiomolybdate attenuates angiogenesis and tumor cell proliferation through the inhibition of superoxide dismutase 1

Clinical Cancer Research

Volumn 12, Issue 16, 2006, Pages 4974-4982

  Juarez, Jose C ^a   Betancourt Jr , Oscar ^a   Pirie Shepherd, Steven R ^a   Guan, Xiaojun ^a   Price, Melissa L ^a   Shaw, David E ^b   Mazar, Andrew P ^a   Doñate, Fernando ^a  

^a Attenuon LLC   (United States)

^b D E SHAW RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ATN 224; BENZOIC ACID; CHLORIDE; CHOLINE; COPPER; COPPER ZINC SUPEROXIDE DISMUTASE; MANGANESE DERIVATIVE; MATRIGEL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PORPHYRIN DERIVATIVE; SODIUM CHLORIDE; SUPEROXIDE; TETRATHIOMOLYBDIC ACID; UNCLASSIFIED DRUG; ZINC;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; APOPTOSIS; ARTICLE; BINDING AFFINITY; CATALYSIS; CELL CULTURE; CELL LEVEL; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG BINDING; DRUG EFFECT; DRUG INFORMATION; DRUG INHIBITION; DRUG MECHANISM; DRUG TARGETING; ENDOTHELIUM CELL; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN CELL; IN VITRO STUDY; MULTIPLE MYELOMA; MYELOID LEUKEMIA; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; STEADY STATE; TUMOR CELL; TUMOR GROWTH;

ANGIOGENESIS INHIBITORS; APOPTOSIS; CELL PROLIFERATION; COPPER; ENDOTHELIAL CELLS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MOLYBDENUM; MULTIPLE MYELOMA; PHOSPHORYLATION; SUPEROXIDE DISMUTASE;

EID: 33748340865     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-06-0171     Document Type: Article

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