메뉴 건너뛰기




Volumn 29, Issue 4, 2009, Pages 830-839

Cerebral haemodynamic response or excitability is not affected by sildenafil

Author keywords

Magnetic resonance imaging; Migraine; Sildenafil; Vascular response; Visual evoked potentials; Women

Indexed keywords

SILDENAFIL;

EID: 63949087842     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2009.10     Document Type: Article
Times cited : (28)

References (43)
  • 2
    • 0032445219 scopus 로고    scopus 로고
    • Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes
    • Ballard SA, Gingell CJ, Tang K, Turner LA, Price ME, Naylor AM (1998) Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes. J Urol 159:2164-71
    • (1998) J Urol , vol.159 , pp. 2164-2171
    • Ballard, S.A.1    Gingell, C.J.2    Tang, K.3    Turner, L.A.4    Price, M.E.5    Naylor, A.M.6
  • 3
    • 4243064965 scopus 로고    scopus 로고
    • Modulation of synaptic function by cGMP and cGMP-gated cation channels
    • Barnstable CJ, Wei JY, Han MH (2004) Modulation of synaptic function by cGMP and cGMP-gated cation channels. Neurochem Int 45:875-84
    • (2004) Neurochem Int , vol.45 , pp. 875-884
    • Barnstable, C.J.1    Wei, J.Y.2    Han, M.H.3
  • 4
    • 33748686575 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterases: Molecular regulation to clinical use
    • Bender AT, Beavo JA (2006) Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use. Pharmacol Rev 58:488-520
    • (2006) Pharmacol Rev , vol.58 , pp. 488-520
    • Bender, A.T.1    Beavo, J.A.2
  • 5
    • 33646928617 scopus 로고    scopus 로고
    • Functional imaging of the trigeminal system: Applications to migraine pathophysiology
    • Borsook D, Burstein R, Moulton E, Becerra L (2006) Functional imaging of the trigeminal system: applications to migraine pathophysiology. Headache 46(Suppl 1): S32-8
    • (2006) Headache , vol.46 , Issue.SUPPL. 1
    • Borsook, D.1    Burstein, R.2    Moulton, E.3    Becerra, L.4
  • 6
    • 0037046986 scopus 로고    scopus 로고
    • Functional MRI-BOLD of brainstem structures during visually triggered migraine
    • Cao Y, Aurora SK, Nagesh V, Patel SC, Welch KM (2002) Functional MRI-BOLD of brainstem structures during visually triggered migraine. Neurology 59:72-8
    • (2002) Neurology , vol.59 , pp. 72-78
    • Cao, Y.1    Aurora, S.K.2    Nagesh, V.3    Patel, S.C.4    Welch, K.M.5
  • 7
    • 0033553509 scopus 로고    scopus 로고
    • Cyclic GMP phosphodiesterase-5: Target of sildenafil
    • Corbin JD, Francis SH (1999) Cyclic GMP phosphodiesterase-5: target of sildenafil. J Biol Chem 274:13729-32
    • (1999) J Biol Chem , vol.274 , pp. 13729-13732
    • Corbin, J.D.1    Francis, S.H.2
  • 10
    • 45149088480 scopus 로고    scopus 로고
    • Concepts of neural nitric oxidemediated transmission
    • Garthwaite J (2008) Concepts of neural nitric oxidemediated transmission. Eur J Neurosci 27:2783-802
    • (2008) Eur J Neurosci , vol.27 , pp. 2783-2802
    • Garthwaite, J.1
  • 11
    • 0035962999 scopus 로고    scopus 로고
    • Expression of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in mouse tissues and cell lines using an antibody against the enzyme aminoterminal domain
    • Giordano D, De Stefano ME, Citro G, Modica A, Giorgi M (2001) Expression of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in mouse tissues and cell lines using an antibody against the enzyme aminoterminal domain. Biochim Biophys Acta 1539:16-27
    • (2001) Biochim Biophys Acta , vol.1539 , pp. 16-27
    • Giordano, D.1    De Stefano, M.E.2    Citro, G.3    Modica, A.4    Giorgi, M.5
  • 12
    • 33845882288 scopus 로고    scopus 로고
    • Recent advances in understanding migraine mechanisms, molecules and therapeutics
    • Goadsby PJ (2007) Recent advances in understanding migraine mechanisms, molecules and therapeutics. Trends Mol Med 13:39-44
    • (2007) Trends Mol Med , vol.13 , pp. 39-44
    • Goadsby, P.J.1
  • 13
    • 33645809129 scopus 로고    scopus 로고
    • Perivascular nerves and the regulation of cerebrovascular tone
    • Hamel E (2006) Perivascular nerves and the regulation of cerebrovascular tone. J Appl Physiol 100:1059-64
    • (2006) J Appl Physiol , vol.100 , pp. 1059-1064
    • Hamel, E.1
  • 15
    • 25644455936 scopus 로고    scopus 로고
    • The possible role of the NO-cGMP pathway in nociception: Different spinal and supraspinal action of enzyme blockers on rat dorsal horn neurones
    • Hoheisel U, Unger T, Mense S (2005) The possible role of the NO-cGMP pathway in nociception: different spinal and supraspinal action of enzyme blockers on rat dorsal horn neurones. Pain 117:358-67
    • (2005) Pain , vol.117 , pp. 358-367
    • Hoheisel, U.1    Unger, T.2    Mense, S.3
  • 16
    • 0024333249 scopus 로고
    • Intravenous nitroglycerin as an experimental model of vascular headache. Basic characteristics
    • Iversen HK, Olesen J, Tfelt Hansen P (1989) Intravenous nitroglycerin as an experimental model of vascular headache. Basic characteristics. Pain 38:17-24
    • (1989) Pain , vol.38 , pp. 17-24
    • Iversen, H.K.1    Olesen, J.2    Tfelt Hansen, P.3
  • 17
    • 33745906556 scopus 로고    scopus 로고
    • Phosphodiesterase 3 and 5 and cyclic nucleotidegated ion channel expression in rat trigeminovascular system
    • Kruse LS, Sandholdt NT, Gammeltoft S, Olesen J, Kruuse C (2006) Phosphodiesterase 3 and 5 and cyclic nucleotidegated ion channel expression in rat trigeminovascular system. Neurosci Lett 404:202-7
    • (2006) Neurosci Lett , vol.404 , pp. 202-207
    • Kruse, L.S.1    Sandholdt, N.T.2    Gammeltoft, S.3    Olesen, J.4    Kruuse, C.5
  • 19
    • 0037224354 scopus 로고    scopus 로고
    • Migraine can be induced by sildenafil without changes in middle cerebral artery diameter
    • Kruuse C, Thomsen LL, Birk S, Olesen J (2003) Migraine can be induced by sildenafil without changes in middle cerebral artery diameter. Brain 126:241-7
    • (2003) Brain , vol.126 , pp. 241-247
    • Kruuse, C.1    Thomsen, L.L.2    Birk, S.3    Olesen, J.4
  • 20
    • 0036713960 scopus 로고    scopus 로고
    • The phosphodiesterase 5 inhibitor sildenafil has no effect on cerebral blood flow or blood velocity, but nevertheless induces headache in healthy subjects
    • Kruuse C, Thomsen LL, Jacobsen TB, Olesen J (2002) The phosphodiesterase 5 inhibitor sildenafil has no effect on cerebral blood flow or blood velocity, but nevertheless induces headache in healthy subjects. J Cereb Blood Flow Metab 22:1124-31
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 1124-1131
    • Kruuse, C.1    Thomsen, L.L.2    Jacobsen, T.B.3    Olesen, J.4
  • 22
    • 3142777732 scopus 로고    scopus 로고
    • Modulation of dural nociceptor mechanosensitivity by the nitric oxide-cyclic GMP signaling cascade
    • Levy D, Strassman AM (2004) Modulation of dural nociceptor mechanosensitivity by the nitric oxide-cyclic GMP signaling cascade. J Neurophysiol 92:766-72
    • (2004) J Neurophysiol , vol.92 , pp. 766-772
    • Levy, D.1    Strassman, A.M.2
  • 23
    • 33846191628 scopus 로고    scopus 로고
    • Angiogenesis and improved cerebral blood flow in the ischemic boundary area detected by MRI after administration of sildenafil to rats with embolic stroke
    • Li L, Jiang Q, Zhang L, Ding G, Gang Zhang Z, Li Q, Ewing JR, Lu M, Panda S, Ledbetter KA, Whitton PA, Chopp M (2007) Angiogenesis and improved cerebral blood flow in the ischemic boundary area detected by MRI after administration of sildenafil to rats with embolic stroke. Brain Res 1132:185-92
    • (2007) Brain Res , vol.1132 , pp. 185-192
    • Li, L.1    Jiang, Q.2    Zhang, L.3    Ding, G.4    Gang Zhang, Z.5    Li, Q.6    Ewing, J.R.7    Lu, M.8    Panda, S.9    Ledbetter, K.A.10    Whitton, P.A.11    Chopp, M.12
  • 25
    • 0033019663 scopus 로고    scopus 로고
    • The trigeminovascular system in humans: Pathophysiologic implications for primary headache syndromes of the neural influences on the cerebral circulation
    • May A, Goadsby PJ (1999) The trigeminovascular system in humans: pathophysiologic implications for primary headache syndromes of the neural influences on the cerebral circulation. J Cereb Blood Flow Metab 19:115-27
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 115-127
    • May, A.1    Goadsby, P.J.2
  • 26
    • 0242349756 scopus 로고    scopus 로고
    • Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension
    • Michelakis ED, Tymchak W, Noga M, Webster L, Wu XC, Lien D, Wang SH, Modry D, Archer SL (2003) Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension. Circulation 108:2066-9
    • (2003) Circulation , vol.108 , pp. 2066-2069
    • Michelakis, E.D.1    Tymchak, W.2    Noga, M.3    Webster, L.4    Wu, X.C.5    Lien, D.6    Wang, S.H.7    Modry, D.8    Archer, S.L.9
  • 27
    • 0036020153 scopus 로고    scopus 로고
    • Neurologic, psychological, and aggressive disturbances with sildenafil
    • Milman HA, Arnold SB (2002) Neurologic, psychological, and aggressive disturbances with sildenafil. Ann Pharmacother 36:1129-34
    • (2002) Ann Pharmacother , vol.36 , pp. 1129-1134
    • Milman, H.A.1    Arnold, S.B.2
  • 28
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RM, Higgs EA (1991) Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 43:109-42
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 29
    • 55149086558 scopus 로고    scopus 로고
    • The role of nitric oxide (NO) in migraine, tension-type headache and cluster headache
    • Olesen J (2008) The role of nitric oxide (NO) in migraine, tension-type headache and cluster headache. Pharmacol Ther 120:157-71
    • (2008) Pharmacol Ther , vol.120 , pp. 157-171
    • Olesen, J.1
  • 31
    • 0027473204 scopus 로고
    • Nitric oxide synthesis and regional cerebral blood flow responses to hypercapnia and hypoxia in the rat
    • Pelligrino DA, Koenig HM, Albrecht RF (1993) Nitric oxide synthesis and regional cerebral blood flow responses to hypercapnia and hypoxia in the rat. J Cereb Blood Flow Metab 13:80-7
    • (1993) J Cereb Blood Flow Metab , vol.13 , pp. 80-87
    • Pelligrino, D.A.1    Koenig, H.M.2    Albrecht, R.F.3
  • 33
    • 0001301238 scopus 로고
    • Experimental studies on headache
    • Ray B, Wolff H (1940) Experimental studies on headache. Arch Surg 41:813-56
    • (1940) Arch Surg , vol.41 , pp. 813-856
    • Ray, B.1    Wolff, H.2
  • 34
    • 0242579616 scopus 로고    scopus 로고
    • Overview of phosphodiesterase 5 inhibition in erectile dysfunction
    • Rosen RC, Kostis JB (2003) Overview of phosphodiesterase 5 inhibition in erectile dysfunction. Am J Cardiol 92:9M-18M
    • (2003) Am J Cardiol , vol.92
    • Rosen, R.C.1    Kostis, J.B.2
  • 36
    • 41449090262 scopus 로고    scopus 로고
    • Visual evoked potential latency, amplitude and habituation in migraine: A longitudinal study
    • Sand T, Zhitniy N, White LR, Stovner LJ (2008) Visual evoked potential latency, amplitude and habituation in migraine: a longitudinal study. Clin Neurophysiol 119:1020-7
    • (2008) Clin Neurophysiol , vol.119 , pp. 1020-1027
    • Sand, T.1    Zhitniy, N.2    White, L.R.3    Stovner, L.J.4
  • 37
    • 33750610790 scopus 로고    scopus 로고
    • Impaired cerebrovascular reactivity after cortical spreading depression in rats: Restoration by nitric oxide or cGMP
    • Scheckenbach KE, Dreier JP, Dirnagl U, Lindauer U (2006) Impaired cerebrovascular reactivity after cortical spreading depression in rats: restoration by nitric oxide or cGMP. Exp Neurol 202:449-55
    • (2006) Exp Neurol , vol.202 , pp. 449-455
    • Scheckenbach, K.E.1    Dreier, J.P.2    Dirnagl, U.3    Lindauer, U.4
  • 38
    • 0038540206 scopus 로고    scopus 로고
    • Evoked potentials and transcranial magnetic stimulation in migraine: Published data and viewpoint on their pathophysiologic significance
    • Schoenen J, Ambrosini A, Sandor PS, Maertens de Noordhout A (2003) Evoked potentials and transcranial magnetic stimulation in migraine: published data and viewpoint on their pathophysiologic significance. Clin Neurophysiol 114:955-72
    • (2003) Clin Neurophysiol , vol.114 , pp. 955-972
    • Schoenen, J.1    Ambrosini, A.2    Sandor, P.S.3    Maertens de Noordhout, A.4
  • 39
    • 0028118203 scopus 로고
    • A nitric oxide donor (nitroglycerin) triggers genuine migraine attacks
    • Thomsen LL, Kruuse C, Iversen HK, Olesen J (1994) A nitric oxide donor (nitroglycerin) triggers genuine migraine attacks. Eur J Neurol 1:73-80
    • (1994) Eur J Neurol , vol.1 , pp. 73-80
    • Thomsen, L.L.1    Kruuse, C.2    Iversen, H.K.3    Olesen, J.4
  • 40
    • 47549092919 scopus 로고    scopus 로고
    • The effect of sildenafil on the altered thoracic aorta smooth muscle responses in rat preeclampsia model
    • Turgut NH, Temiz TK, Bagcivan I, Turgut B, Gulturk S, Karadas B (2008) The effect of sildenafil on the altered thoracic aorta smooth muscle responses in rat preeclampsia model. Eur J Pharmacol 589:180-7
    • (2008) Eur J Pharmacol , vol.589 , pp. 180-187
    • Turgut, N.H.1    Temiz, T.K.2    Bagcivan, I.3    Turgut, B.4    Gulturk, S.5    Karadas, B.6
  • 43
    • 0036843061 scopus 로고    scopus 로고
    • Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats
    • Zhang R, Wang Y, Zhang L, Zhang Z, Tsang W, Lu M, Chopp M (2002) Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats. Stroke 33:2675-80
    • (2002) Stroke , vol.33 , pp. 2675-2680
    • Zhang, R.1    Wang, Y.2    Zhang, L.3    Zhang, Z.4    Tsang, W.5    Lu, M.6    Chopp, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.