-
1
-
-
0037383775
-
Effect of sildenafil (Viagra) on cerebral blood flow velocity: A pilot study
-
Arnavaz A, Aurich A,Weissenborn K, Hartmann U, Emrich HM, Schneider U (2003) Effect of sildenafil (Viagra) on cerebral blood flow velocity: a pilot study. Psychiatry Res 122:207-9
-
(2003)
Psychiatry Res
, vol.122
, pp. 207-209
-
-
Arnavaz, A.1
Aurich, A.2
Weissenborn, K.3
Hartmann, U.4
Emrich, H.M.5
Schneider, U.6
-
2
-
-
0032445219
-
Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes
-
Ballard SA, Gingell CJ, Tang K, Turner LA, Price ME, Naylor AM (1998) Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes. J Urol 159:2164-71
-
(1998)
J Urol
, vol.159
, pp. 2164-2171
-
-
Ballard, S.A.1
Gingell, C.J.2
Tang, K.3
Turner, L.A.4
Price, M.E.5
Naylor, A.M.6
-
3
-
-
4243064965
-
Modulation of synaptic function by cGMP and cGMP-gated cation channels
-
Barnstable CJ, Wei JY, Han MH (2004) Modulation of synaptic function by cGMP and cGMP-gated cation channels. Neurochem Int 45:875-84
-
(2004)
Neurochem Int
, vol.45
, pp. 875-884
-
-
Barnstable, C.J.1
Wei, J.Y.2
Han, M.H.3
-
4
-
-
33748686575
-
Cyclic nucleotide phosphodiesterases: Molecular regulation to clinical use
-
Bender AT, Beavo JA (2006) Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use. Pharmacol Rev 58:488-520
-
(2006)
Pharmacol Rev
, vol.58
, pp. 488-520
-
-
Bender, A.T.1
Beavo, J.A.2
-
5
-
-
33646928617
-
Functional imaging of the trigeminal system: Applications to migraine pathophysiology
-
Borsook D, Burstein R, Moulton E, Becerra L (2006) Functional imaging of the trigeminal system: applications to migraine pathophysiology. Headache 46(Suppl 1): S32-8
-
(2006)
Headache
, vol.46
, Issue.SUPPL. 1
-
-
Borsook, D.1
Burstein, R.2
Moulton, E.3
Becerra, L.4
-
6
-
-
0037046986
-
Functional MRI-BOLD of brainstem structures during visually triggered migraine
-
Cao Y, Aurora SK, Nagesh V, Patel SC, Welch KM (2002) Functional MRI-BOLD of brainstem structures during visually triggered migraine. Neurology 59:72-8
-
(2002)
Neurology
, vol.59
, pp. 72-78
-
-
Cao, Y.1
Aurora, S.K.2
Nagesh, V.3
Patel, S.C.4
Welch, K.M.5
-
7
-
-
0033553509
-
Cyclic GMP phosphodiesterase-5: Target of sildenafil
-
Corbin JD, Francis SH (1999) Cyclic GMP phosphodiesterase-5: target of sildenafil. J Biol Chem 274:13729-32
-
(1999)
J Biol Chem
, vol.274
, pp. 13729-13732
-
-
Corbin, J.D.1
Francis, S.H.2
-
8
-
-
51649114103
-
Posterior cerebral hypoperfusion in migraine without aura
-
Denuelle M, Fabre N, Payoux P, Chollet F, Geraud G (2008) Posterior cerebral hypoperfusion in migraine without aura. Cephalalgia 28:856-62
-
(2008)
Cephalalgia
, vol.28
, pp. 856-862
-
-
Denuelle, M.1
Fabre, N.2
Payoux, P.3
Chollet, F.4
Geraud, G.5
-
9
-
-
25444473998
-
Sildenafil increases cerebrovascular reactivity: A transcranial Doppler study
-
Diomedi M, Sallustio F, Rizzato B, Ferrante F, Leone G, Spera E, Scarfini M, Bernardi G (2005) Sildenafil increases cerebrovascular reactivity: a transcranial Doppler study. Neurology 65:919-21
-
(2005)
Neurology
, vol.65
, pp. 919-921
-
-
Diomedi, M.1
Sallustio, F.2
Rizzato, B.3
Ferrante, F.4
Leone, G.5
Spera, E.6
Scarfini, M.7
Bernardi, G.8
-
10
-
-
45149088480
-
Concepts of neural nitric oxidemediated transmission
-
Garthwaite J (2008) Concepts of neural nitric oxidemediated transmission. Eur J Neurosci 27:2783-802
-
(2008)
Eur J Neurosci
, vol.27
, pp. 2783-2802
-
-
Garthwaite, J.1
-
11
-
-
0035962999
-
Expression of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in mouse tissues and cell lines using an antibody against the enzyme aminoterminal domain
-
Giordano D, De Stefano ME, Citro G, Modica A, Giorgi M (2001) Expression of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in mouse tissues and cell lines using an antibody against the enzyme aminoterminal domain. Biochim Biophys Acta 1539:16-27
-
(2001)
Biochim Biophys Acta
, vol.1539
, pp. 16-27
-
-
Giordano, D.1
De Stefano, M.E.2
Citro, G.3
Modica, A.4
Giorgi, M.5
-
12
-
-
33845882288
-
Recent advances in understanding migraine mechanisms, molecules and therapeutics
-
Goadsby PJ (2007) Recent advances in understanding migraine mechanisms, molecules and therapeutics. Trends Mol Med 13:39-44
-
(2007)
Trends Mol Med
, vol.13
, pp. 39-44
-
-
Goadsby, P.J.1
-
13
-
-
33645809129
-
Perivascular nerves and the regulation of cerebrovascular tone
-
Hamel E (2006) Perivascular nerves and the regulation of cerebrovascular tone. J Appl Physiol 100:1059-64
-
(2006)
J Appl Physiol
, vol.100
, pp. 1059-1064
-
-
Hamel, E.1
-
14
-
-
57049189724
-
Brainstem functional magnetic resonance imaging: Disentangling signal from physiological noise
-
Harvey AK, Pattinson KT, Brooks JC, Mayhew SD, Jenkinson M, Wise RG (2008) Brainstem functional magnetic resonance imaging: disentangling signal from physiological noise. J Magn Reson Imaging 28: 1337-44
-
(2008)
J Magn Reson Imaging
, vol.28
, pp. 1337-1344
-
-
Harvey, A.K.1
Pattinson, K.T.2
Brooks, J.C.3
Mayhew, S.D.4
Jenkinson, M.5
Wise, R.G.6
-
15
-
-
25644455936
-
The possible role of the NO-cGMP pathway in nociception: Different spinal and supraspinal action of enzyme blockers on rat dorsal horn neurones
-
Hoheisel U, Unger T, Mense S (2005) The possible role of the NO-cGMP pathway in nociception: different spinal and supraspinal action of enzyme blockers on rat dorsal horn neurones. Pain 117:358-67
-
(2005)
Pain
, vol.117
, pp. 358-367
-
-
Hoheisel, U.1
Unger, T.2
Mense, S.3
-
16
-
-
0024333249
-
Intravenous nitroglycerin as an experimental model of vascular headache. Basic characteristics
-
Iversen HK, Olesen J, Tfelt Hansen P (1989) Intravenous nitroglycerin as an experimental model of vascular headache. Basic characteristics. Pain 38:17-24
-
(1989)
Pain
, vol.38
, pp. 17-24
-
-
Iversen, H.K.1
Olesen, J.2
Tfelt Hansen, P.3
-
17
-
-
33745906556
-
Phosphodiesterase 3 and 5 and cyclic nucleotidegated ion channel expression in rat trigeminovascular system
-
Kruse LS, Sandholdt NT, Gammeltoft S, Olesen J, Kruuse C (2006) Phosphodiesterase 3 and 5 and cyclic nucleotidegated ion channel expression in rat trigeminovascular system. Neurosci Lett 404:202-7
-
(2006)
Neurosci Lett
, vol.404
, pp. 202-207
-
-
Kruse, L.S.1
Sandholdt, N.T.2
Gammeltoft, S.3
Olesen, J.4
Kruuse, C.5
-
18
-
-
26444510813
-
Phosphodiesterase 5 and effects of sildenafil on cerebral arteries of man and guinea pig
-
Kruuse C, Khurana TS, Rybalkin SD, Birk S, Engel U, Edvinsson L, Olesen J (2005) Phosphodiesterase 5 and effects of sildenafil on cerebral arteries of man and guinea pig. Eur J Pharmacol 521:105-14
-
(2005)
Eur J Pharmacol
, vol.521
, pp. 105-114
-
-
Kruuse, C.1
Khurana, T.S.2
Rybalkin, S.D.3
Birk, S.4
Engel, U.5
Edvinsson, L.6
Olesen, J.7
-
19
-
-
0037224354
-
Migraine can be induced by sildenafil without changes in middle cerebral artery diameter
-
Kruuse C, Thomsen LL, Birk S, Olesen J (2003) Migraine can be induced by sildenafil without changes in middle cerebral artery diameter. Brain 126:241-7
-
(2003)
Brain
, vol.126
, pp. 241-247
-
-
Kruuse, C.1
Thomsen, L.L.2
Birk, S.3
Olesen, J.4
-
20
-
-
0036713960
-
The phosphodiesterase 5 inhibitor sildenafil has no effect on cerebral blood flow or blood velocity, but nevertheless induces headache in healthy subjects
-
Kruuse C, Thomsen LL, Jacobsen TB, Olesen J (2002) The phosphodiesterase 5 inhibitor sildenafil has no effect on cerebral blood flow or blood velocity, but nevertheless induces headache in healthy subjects. J Cereb Blood Flow Metab 22:1124-31
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 1124-1131
-
-
Kruuse, C.1
Thomsen, L.L.2
Jacobsen, T.B.3
Olesen, J.4
-
21
-
-
0036285460
-
CGRP may play a causative role in migraine
-
Lassen L, Haderslev P, Jacobsen V, Iversen H, Sperling B, Olesen J (2002) CGRP may play a causative role in migraine. Cephalalgia 22:54-61
-
(2002)
Cephalalgia
, vol.22
, pp. 54-61
-
-
Lassen, L.1
Haderslev, P.2
Jacobsen, V.3
Iversen, H.4
Sperling, B.5
Olesen, J.6
-
22
-
-
3142777732
-
Modulation of dural nociceptor mechanosensitivity by the nitric oxide-cyclic GMP signaling cascade
-
Levy D, Strassman AM (2004) Modulation of dural nociceptor mechanosensitivity by the nitric oxide-cyclic GMP signaling cascade. J Neurophysiol 92:766-72
-
(2004)
J Neurophysiol
, vol.92
, pp. 766-772
-
-
Levy, D.1
Strassman, A.M.2
-
23
-
-
33846191628
-
Angiogenesis and improved cerebral blood flow in the ischemic boundary area detected by MRI after administration of sildenafil to rats with embolic stroke
-
Li L, Jiang Q, Zhang L, Ding G, Gang Zhang Z, Li Q, Ewing JR, Lu M, Panda S, Ledbetter KA, Whitton PA, Chopp M (2007) Angiogenesis and improved cerebral blood flow in the ischemic boundary area detected by MRI after administration of sildenafil to rats with embolic stroke. Brain Res 1132:185-92
-
(2007)
Brain Res
, vol.1132
, pp. 185-192
-
-
Li, L.1
Jiang, Q.2
Zhang, L.3
Ding, G.4
Gang Zhang, Z.5
Li, Q.6
Ewing, J.R.7
Lu, M.8
Panda, S.9
Ledbetter, K.A.10
Whitton, P.A.11
Chopp, M.12
-
25
-
-
0033019663
-
The trigeminovascular system in humans: Pathophysiologic implications for primary headache syndromes of the neural influences on the cerebral circulation
-
May A, Goadsby PJ (1999) The trigeminovascular system in humans: pathophysiologic implications for primary headache syndromes of the neural influences on the cerebral circulation. J Cereb Blood Flow Metab 19:115-27
-
(1999)
J Cereb Blood Flow Metab
, vol.19
, pp. 115-127
-
-
May, A.1
Goadsby, P.J.2
-
26
-
-
0242349756
-
Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension
-
Michelakis ED, Tymchak W, Noga M, Webster L, Wu XC, Lien D, Wang SH, Modry D, Archer SL (2003) Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension. Circulation 108:2066-9
-
(2003)
Circulation
, vol.108
, pp. 2066-2069
-
-
Michelakis, E.D.1
Tymchak, W.2
Noga, M.3
Webster, L.4
Wu, X.C.5
Lien, D.6
Wang, S.H.7
Modry, D.8
Archer, S.L.9
-
27
-
-
0036020153
-
Neurologic, psychological, and aggressive disturbances with sildenafil
-
Milman HA, Arnold SB (2002) Neurologic, psychological, and aggressive disturbances with sildenafil. Ann Pharmacother 36:1129-34
-
(2002)
Ann Pharmacother
, vol.36
, pp. 1129-1134
-
-
Milman, H.A.1
Arnold, S.B.2
-
28
-
-
0025883342
-
Nitric oxide: Physiology, pathophysiology, and pharmacology
-
Moncada S, Palmer RM, Higgs EA (1991) Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 43:109-42
-
(1991)
Pharmacol Rev
, vol.43
, pp. 109-142
-
-
Moncada, S.1
Palmer, R.M.2
Higgs, E.A.3
-
29
-
-
55149086558
-
The role of nitric oxide (NO) in migraine, tension-type headache and cluster headache
-
Olesen J (2008) The role of nitric oxide (NO) in migraine, tension-type headache and cluster headache. Pharmacol Ther 120:157-71
-
(2008)
Pharmacol Ther
, vol.120
, pp. 157-171
-
-
Olesen, J.1
-
30
-
-
20444446700
-
Postmortem distribution of sildenafil in histological material
-
Pagani S, Mirtella D, Mencarelli R, Rodriguez D, Cingolani M (2005) Postmortem distribution of sildenafil in histological material. J Anal Toxicol 29:254-7
-
(2005)
J Anal Toxicol
, vol.29
, pp. 254-257
-
-
Pagani, S.1
Mirtella, D.2
Mencarelli, R.3
Rodriguez, D.4
Cingolani, M.5
-
31
-
-
0027473204
-
Nitric oxide synthesis and regional cerebral blood flow responses to hypercapnia and hypoxia in the rat
-
Pelligrino DA, Koenig HM, Albrecht RF (1993) Nitric oxide synthesis and regional cerebral blood flow responses to hypercapnia and hypoxia in the rat. J Cereb Blood Flow Metab 13:80-7
-
(1993)
J Cereb Blood Flow Metab
, vol.13
, pp. 80-87
-
-
Pelligrino, D.A.1
Koenig, H.M.2
Albrecht, R.F.3
-
33
-
-
0001301238
-
Experimental studies on headache
-
Ray B, Wolff H (1940) Experimental studies on headache. Arch Surg 41:813-56
-
(1940)
Arch Surg
, vol.41
, pp. 813-856
-
-
Ray, B.1
Wolff, H.2
-
34
-
-
0242579616
-
Overview of phosphodiesterase 5 inhibition in erectile dysfunction
-
Rosen RC, Kostis JB (2003) Overview of phosphodiesterase 5 inhibition in erectile dysfunction. Am J Cardiol 92:9M-18M
-
(2003)
Am J Cardiol
, vol.92
-
-
Rosen, R.C.1
Kostis, J.B.2
-
35
-
-
33645788620
-
Sildenafil improves dynamic vascular function in the brain: Studies in patients with pulmonary hypertension
-
Rosengarten B, Schermuly RT, Voswinckel R, Kohstall MG, Olschewski H, Weissmann N, Seeger W, Kaps M, Grimminger F, Ghofrani HA (2006) Sildenafil improves dynamic vascular function in the brain: studies in patients with pulmonary hypertension. Cerebrovasc Dis 21:194-200
-
(2006)
Cerebrovasc Dis
, vol.21
, pp. 194-200
-
-
Rosengarten, B.1
Schermuly, R.T.2
Voswinckel, R.3
Kohstall, M.G.4
Olschewski, H.5
Weissmann, N.6
Seeger, W.7
Kaps, M.8
Grimminger, F.9
Ghofrani, H.A.10
-
36
-
-
41449090262
-
Visual evoked potential latency, amplitude and habituation in migraine: A longitudinal study
-
Sand T, Zhitniy N, White LR, Stovner LJ (2008) Visual evoked potential latency, amplitude and habituation in migraine: a longitudinal study. Clin Neurophysiol 119:1020-7
-
(2008)
Clin Neurophysiol
, vol.119
, pp. 1020-1027
-
-
Sand, T.1
Zhitniy, N.2
White, L.R.3
Stovner, L.J.4
-
37
-
-
33750610790
-
Impaired cerebrovascular reactivity after cortical spreading depression in rats: Restoration by nitric oxide or cGMP
-
Scheckenbach KE, Dreier JP, Dirnagl U, Lindauer U (2006) Impaired cerebrovascular reactivity after cortical spreading depression in rats: restoration by nitric oxide or cGMP. Exp Neurol 202:449-55
-
(2006)
Exp Neurol
, vol.202
, pp. 449-455
-
-
Scheckenbach, K.E.1
Dreier, J.P.2
Dirnagl, U.3
Lindauer, U.4
-
38
-
-
0038540206
-
Evoked potentials and transcranial magnetic stimulation in migraine: Published data and viewpoint on their pathophysiologic significance
-
Schoenen J, Ambrosini A, Sandor PS, Maertens de Noordhout A (2003) Evoked potentials and transcranial magnetic stimulation in migraine: published data and viewpoint on their pathophysiologic significance. Clin Neurophysiol 114:955-72
-
(2003)
Clin Neurophysiol
, vol.114
, pp. 955-972
-
-
Schoenen, J.1
Ambrosini, A.2
Sandor, P.S.3
Maertens de Noordhout, A.4
-
39
-
-
0028118203
-
A nitric oxide donor (nitroglycerin) triggers genuine migraine attacks
-
Thomsen LL, Kruuse C, Iversen HK, Olesen J (1994) A nitric oxide donor (nitroglycerin) triggers genuine migraine attacks. Eur J Neurol 1:73-80
-
(1994)
Eur J Neurol
, vol.1
, pp. 73-80
-
-
Thomsen, L.L.1
Kruuse, C.2
Iversen, H.K.3
Olesen, J.4
-
40
-
-
47549092919
-
The effect of sildenafil on the altered thoracic aorta smooth muscle responses in rat preeclampsia model
-
Turgut NH, Temiz TK, Bagcivan I, Turgut B, Gulturk S, Karadas B (2008) The effect of sildenafil on the altered thoracic aorta smooth muscle responses in rat preeclampsia model. Eur J Pharmacol 589:180-7
-
(2008)
Eur J Pharmacol
, vol.589
, pp. 180-187
-
-
Turgut, N.H.1
Temiz, T.K.2
Bagcivan, I.3
Turgut, B.4
Gulturk, S.5
Karadas, B.6
-
41
-
-
0344585989
-
mRNA expression patterns of the cGMPhydrolyzing phosphodiesterases types 2, 5, and 9 during development of the rat brain
-
Van Staveren WC, Steinbusch HW, Markerink-Van Ittersum M, Repaske DR, Goy MF, Kotera J, Omori K, Beavo JA, De Vente J (2003) mRNA expression patterns of the cGMPhydrolyzing phosphodiesterases types 2, 5, and 9 during development of the rat brain. J Comp Neurol 467:566-80
-
(2003)
J Comp Neurol
, vol.467
, pp. 566-580
-
-
Van Staveren, W.C.1
Steinbusch, H.W.2
Markerink-Van Ittersum, M.3
Repaske, D.R.4
Goy, M.F.5
Kotera, J.6
Omori, K.7
Beavo, J.A.8
De Vente, J.9
-
42
-
-
7944230142
-
Type 5 phosphodiesterase inhibition by sildenafil abrogates acute smoking-induced endothelial dysfunction
-
Vlachopoulos C, Tsekoura D, Alexopoulos N, Panagiotakos D, Aznaouridis K, Stefanadis C (2004) Type 5 phosphodiesterase inhibition by sildenafil abrogates acute smoking-induced endothelial dysfunction. Am J Hypertens 17:1040-4
-
(2004)
Am J Hypertens
, vol.17
, pp. 1040-1044
-
-
Vlachopoulos, C.1
Tsekoura, D.2
Alexopoulos, N.3
Panagiotakos, D.4
Aznaouridis, K.5
Stefanadis, C.6
-
43
-
-
0036843061
-
Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats
-
Zhang R, Wang Y, Zhang L, Zhang Z, Tsang W, Lu M, Chopp M (2002) Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats. Stroke 33:2675-80
-
(2002)
Stroke
, vol.33
, pp. 2675-2680
-
-
Zhang, R.1
Wang, Y.2
Zhang, L.3
Zhang, Z.4
Tsang, W.5
Lu, M.6
Chopp, M.7
|