Hedgehog signaling is involved in differentiation of normal colonic tissue rather than in tumor proliferation

Virchows Archiv

Volumn 454, Issue 4, 2009, Pages 369-379

  Alinger, Beate ^a   Kiesslich, Tobias ^a   Datz, Christian ^a   Aberger, Fritz ^b   Strasser, Felix ^a   Berr, Frieder ^a   Dietze, Otto ^a   Kaserer, Klaus ^c   Hauser Kronberger, Cornelia ^a  

^a PARACELSUS MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF SALZBURG   (Austria)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Colon cancer; Differentiation; Hedgehog pathway; Proliferation; Stem cells

Indexed keywords

CYCLOPAMINE; PROTEIN PATCHED; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3;

ARTICLE; CANCER CELL CULTURE; CELL AGGREGATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN CACO 2; COLON ADENOCARCINOMA; COLON ADENOMA; COLON CARCINOGENESIS; COLON MUCOSA; COLON POLYP; COLON TUMOR; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; INTESTINE CRYPT; MAJOR CLINICAL STUDY; METASTASIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; COLON; COLONIC NEOPLASMS; HEDGEHOG PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TISSUE ARRAY ANALYSIS; VERATRUM ALKALOIDS;

EID: 63949086103     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-009-0753-7     Document Type: Article

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