Novel peptide mimetic inhibitors of hepatitis C serine protease derived from isomannide

Synthesis

Volumn , Issue 4, 2009, Pages 620-626

  Barros, Thalita G ^a   Pinheiro, Sergio ^a   Williamson, John S ^b   Tanuri, Amílcar ^c   Pereira, Helena S ^a,c   Brindeiro, Rodrigo M ^c   Neto, José B A ^c   Antunes, Octávio A C ^c   Muri, Estela M F ^a  

^a FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Antiviral agent; Fused ring systems; Hepatitis c; Isoman nide; Peptides

Indexed keywords

ANTIVIRAL AGENT; BIOLOGICAL STUDIES; CHRONIC LIVER DISEASE; DRUG DEVELOPMENT; FUSED-RING SYSTEMS; HEPATITIS C; ISOMAN-NIDE; LIVER FAILURES; PROTEOLYTIC ENZYMES; SERINE PROTEASE; SERINE PROTEASE INHIBITORS;

AMINO ACIDS; BIOMIMETICS; ENERGY ABSORPTION; HYPERSONIC AERODYNAMICS; LIVER; PEPTIDES;

AMINES;

1,4:3,6 DIANHYDRO 2 [[2 (BENZOYLAMINO) 3 (1 BENZOTHIOPHEN 2 YL)PROPENOYL]AMINO] 5 O BENZYL 2 DEOXY DEXTRO GLUCITOL; 1,4:3,6 DIANHYDRO 2 [[2 (BENZOYLAMINO) 3 (1H INDOL 3 YL)PROPENOYL]AMINO] 5 O BENZYL 2 DEOXY DEXTRO GLUCITOL; 1,4:3,6 DIANHYDRO 2 [[2 (BENZOYLAMINO) 3 (2 FURYL)PROPENOYL]AMINO] 5 O BENZYL 2 DEOXY DEXTRO GLUCITOL; 1,4:3,6 DIANHYDRO 2 [[2 (BENZOYLAMINO) 3 (2 NAPHTHYL)PROPENOYL]AMINO] 5 O BENZYL 2 DEOXY DEXTRO GLUCITOL; 1,4:3,6 DIANHYDRO 2 [[2 (BENZOYLAMINO) 3 (2 THIENYL)PROPENOYL]AMINO] 5 O BENZYL 2 DEOXY DEXTRO GLUCITOL; 1,4:3,6 DIANHYDRO 2 [[2 (BENZOYLAMINO) 3 (3 PYRIDYL)PROPENOYL]AMINO] 5 O BENZYL 2 DEOXY DEXTRO GLUCITOL; 1,4:3,6 DIANHYDRO 2 [[2 (BENZOYLAMINO) 3 (4 BROMOPHENYL)PROPENOYL]AMINO] 5 O BENZYL 2 DEOXY DEXTRO GLUCITOL; 1,4:3,6 DIANHYDRO 2 [[2 (BENZOYLAMINO) 3 (4 CHLOROPHENYL)PROPENOYL]AMINO] 5 O BENZYL 2 DEOXY DEXTRO GLUCITOL; 1,4:3,6 DIANHYDRO 2 [[2 (BENZOYLAMINO) 3 (4 FLUOROPHENYL)PROPENOYL]AMINO] 5 O BENZYL 2 DEOXY DEXTRO GLUCITOL; 1,4:3,6 DIANHYDRO 2 [[2 (BENZOYLAMINO) 3 (4 METHOXYPHENYL)PROPENOYL]AMINO] 5 O BENZYL 2 DEOXY DEXTRO GLUCITOL; 1,4:3,6 DIANHYDRO 2 [[2 (BENZOYLAMINO) 3 (BENZOFURAN 2 YL)PROPENOYL]AMINO] 5 O BENZYL 2 DEOXY DEXTRO GLUCITOL; 1,4:3,6 DIANHYDRO 2 [[2 (BENZOYLAMINO) 3 [3,4 (METHYLENEDIOXY)PHENYL]PROPENOYL]AMINO] 5 O BENZYL 2 DEOXY DEXTRO GLUCITOL; 1,4:3,6 DIANHYDRO 2 [[2 (BENZOYLAMINO) 3 [4 (TRIFLUOROMETHYL)PHENYL]PROPENOYL]AMINO] 5 O BENZYL 2 DEOXY DEXTRO GLUCITOL; 1,4:3,6 DIANHYDRO 2 [[2 (BENZOYLAMINO) 3 PHENYLPROPENOYL]AMINO] 5 O BENZYL 2 DEOXY DEXTRO GLUCITOL; 2 [[2 (ACETYLAMINO) 3 (2 THIENYL)PROPENOYL]AMINO] 1,4:3,6 DIANHYDRO 5 O BENZYL 2 DEOXY DEXTRO GLUCITOL; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; HEPATITIS C VIRUS; HUMAN; HUMAN CELL;

EID: 63849194151     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0028-1083332     Document Type: Article

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