Toward a molecular equivalent dose: Use of the medaka model in comparative risk assessment

Comparative Biochemistry and Physiology - C Toxicology and Pharmacology

Volumn 149, Issue 2, 2009, Pages 141-151

  Hobbie, Kristen R ^a,b   DeAngelo, Anthony B ^c   King, Leon C ^c   Winn, Richard N ^d   Law, J McHugh ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b INTEGRATED LABORATORY SYSTEMS   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^d UNIVERSITY OF GEORGIA   (United States)

Author keywords

Adduct; cII; DMN; DNA; Dose response; Medaka; Mutation; Nitrosamines; Risk assessment

Indexed keywords

6 O METHYLGUANINE; 7 METHYLGUANINE; 8 HYDROXYGUANINE; CARCINOGEN; DIMETHYLNITROSAMINE; DRINKING WATER; GENOMIC DNA; METHANEARSONATE DISODIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER MODEL; CARCINOGENESIS; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DOSE RESPONSE; FISCHER 344 RAT; FISH; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIVER CANCER; LIVER CARCINOGENESIS; MUTAGENESIS; NONHUMAN; ORYZIAS; PRIORITY JOURNAL; RAT; RISK ASSESSMENT; SPECIES DIFFERENCE; TRANSGENIC RAT;

ANIMALIA; ORYZIAS LATIPES; ORYZIINAE; RATTUS; RODENTIA;

EID: 63749102686     PISSN: 15320456     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbpc.2008.07.013     Document Type: Article

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