Importance of DNA repair in carcinogenesis: Evidence from transgenic and gene targeting studies

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 477, Issue 1-2, 2001, Pages 41-49

  Ishikawa, Takatoshi ^a   Ide, Fumio ^a   Qin, Xiusheng ^a   Zhang, Shaomin ^a   Takahashi, Yoshihisa ^a   Sekiguchi, Mutsuo ^b   Tanaka, Kiyoji ^c   Nakatsuru, Yoko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b FUKUOKA DENTAL COLLEGE   (Japan)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

Chemical carcinogenesis; DNA repair; Knockout mice; Nucleotide excision repair; O6 methylguanine DNA methyltransferase; Transgenic mice

Indexed keywords

BENZO[A]PYRENE; DIETHYLNITROSAMINE; DIMETHYLBENZ[A]ANTHRACENE; DIMETHYLNITROSAMINE; DNA; LIVER EXTRACT; METALLOTHIONEIN; PROTEIN; PROTEIN XPA; UNCLASSIFIED DRUG; ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DNA REPAIR; DRUG INDUCED DISEASE; ENZYME ACTIVITY; EXCISION REPAIR; GENE TARGETING; HETEROZYGOSITY; HOMOZYGOTE; LIVER; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LUNG; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SKIN PAPILLOMA; SKIN ULCER; TONGUE; TRANSGENIC MOUSE; XERODERMA PIGMENTOSUM;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL TRANSFORMATION, NEOPLASTIC; DISEASE MODELS, ANIMAL; DNA REPAIR; GENE TARGETING; MICE; MICE, TRANSGENIC; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; XERODERMA PIGMENTOSUM;

ADA; MUS MUSCULUS;

EID: 0035796039     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(01)00094-X     Document Type: Article

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