A single amino acid of toll-like receptor 4 that is pivotal for its signal transduction and subcellular localization

Journal of Biological Chemistry

Volumn 284, Issue 6, 2009, Pages 3513-3520

  Yanagimoto, Shintaro ^a,b,c   Tatsuno, Keita ^b   Okugawa, Shu ^b   Kitazawa, Takatoshi ^b   Tsukada, Kunihisa ^b   Koike, Kazuhiko ^b   Kodama, Tatsuhiko ^c   Kimura, Satoshi ^d   Shibasaki, Yoshikazu ^a   Ota, Yasuo ^a,b,e  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d TOKYO TEISHIN HOSPITAL   (Japan)

^e TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CO-PRECIPITATE; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION; PLASMA MEMBRANES; SUBCELLULAR DISTRIBUTION; SUBCELLULAR LOCALIZATIONS; TOLL-LIKE RECEPTOR 4;

AMINATION; AMINES; CELL MEMBRANES; ORGANIC ACIDS; POLYSACCHARIDES; SIGNAL TRANSDUCTION;

AMINO ACIDS;

ALANINE; LEUCINE; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; MYELOID DIFFERENTIATION FACTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; LY96 PROTEIN, HUMAN; LY96 PROTEIN, MOUSE; MULTIPROTEIN COMPLEX; PROTEIN MD 2; TLR4 PROTEIN, HUMAN; TLR4 PROTEIN, MOUSE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; GENETICS; METABOLISM; MISSENSE MUTATION; MOUSE; PHYSIOLOGY; PROTEIN BINDING; PROTEIN TRANSPORT;

BACTERIA (MICROORGANISMS); MURINAE; NEGIBACTERIA;

AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; CELL MEMBRANE; HUMANS; LIPOPOLYSACCHARIDES; LYMPHOCYTE ANTIGEN 96; MICE; MULTIPROTEIN COMPLEXES; MUTATION, MISSENSE; PROTEIN BINDING; PROTEIN TRANSPORT; TOLL-LIKE RECEPTOR 4;

EID: 63649114088     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M803086200     Document Type: Article

References (33)

1. Takeda, K., Kaisho, T., and Akira, S. (2003) Annu. Rev. Immunol. 21, 335-376
2. Hoebe, K., Du, X., Georgel, P., Janssen, E., Tabeta, K., Kim, S. O., Goode, J., Lin, P., Mann, N., Mudd, S., Crozat, K., Sovath, S., Han, J., and Beutler, B. (2003) Nature 424, 743-748
3. Oshiumi, H., Sasai, M., Shida, K., Fujita, T., Matsumoto, M., and Seya, T. (2003) J. Biol. Chem. 278, 49751-49762
4. Yamamoto, M., Sato, S., Mori, K., Hoshino, K., Takeuchi, O., Takeda, K., and Akira, S. (2002) J. Immunol. 169, 6668-6672
5. Qureshi, S. T., Lariviere, L., Leveque, G., Clermont, S., Moore, K. J., Gros, P., and Malo, D. (1999) J. Exp. Med. 189, 615-625
6. Poltorak, A., He, X., Smirnova, I., Liu, M. Y., Van Huffel, C., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., Freudenberg, M., Ricciardi-Castagnoli, P., Layton, B., and Beutler, B. (1998) Science 282, 2085-2088
7. Visintin, A., Mazzoni, A., Spitzer, J. A., and Segal, D. M. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 12156-12161
8. Nishitani, C., Mitsuzawa, H., Hyakushima, N., Sano, H., Matsushima, N., and Kuroki, Y. (2005) Biochem. Biophys. Res. Commun. 328, 586-590
9. Shimazu, R., Akashi, S., Ogata, H., Nagai, Y., Fukudome, K., Miyake, K., and Kimoto, M. (1999) J. Exp. Med. 189, 1777-1782
10. Bonifacino, J. S., and Traub, L. M. (2003) Annu. Rev. Biochem. 72, 395-447
11. Nishimura, N., and Balch, W. E. (1997) Science 277, 556-558
12. Nufer, O., and Hauri, H. P. (2003) Curr. Biol. 13, R391-393
13. Slack, J. L., Schooley, K., Bonnert, T. P., Mitcham, J. L., Qwarnstrom, E. E., Sims, J. E., and Dower, S. K. (2000) J. Biol. Chem. 275, 4670-4678
14. Latz, E., Visintin, A., Lien, E., Fitzgerald, K. A., Monks, B. G., Kurt-Jones, E. A., Golenbock, D. T., and Espevik, T. (2002) J. Biol. Chem. 277, 47834-47843
15. Nagai, Y., Akashi, S., Nagafuku, M., Ogata, M., Iwakura, Y., Akira, S., Kitamura, T., Kosugi, A., Kimoto, M., and Miyake, K. (2002) Nat. Immunol. 3, 667-672
16. Hein, C., and Andre, B. (1997) Mol. Microbiol. 24, 607-616
17. Beutler, B. (2000) Curr. Opin. Immunol. 12, 20-26
18. Akashi, S., Ogata, H., Kirikae, F., Kirikae, T., Kawasaki, K., Nishijima, M., Shimazu, R., Nagai, Y., Fukudome, K., Kimoto, M., and Miyake, K. (2000) Biochem. Biophys. Res. Commun. 268, 172-177
19. Ohnishi, T., Muroi, M., and Tanamoto, K. (2003) Clin. Diagn. Lab. Immunol. 10, 405-410
20. Xu, Y., Tao, X., Shen, B., Horng, T., Medzhitov, R., Manley, J. L., and Tong, L. (2000) Nature 408, 111-115
21. Dunne, A., Ejdeback, M., Ludidi, P. L., O'Neill, L. A., and Gay, N. J. (2003) J. Biol. Chem. 278, 41443-41451
22. Fitzgerald, K. A., Palsson-McDermott, E. M., Bowie, A. G., Jefferies, C. A., Mansell, A. S., Brady, G., Brint, E., Dunne, A., Gray, P., Harte, M. T., McMurray, D., Smith, D. E., Sims, J. E., Bird, T. A., and O'Neill, L. A. (2001) Nature 413, 78-83
23. Horng, T., Barton, G. M., and Medzhitov, R. (2001) Nat. Immunol. 2, 835-841
24. Schroder, N. W., and Schumann, R. R. (2005) Lancet Infect. Dis. 5, 156-164
25. Agnese, D. M., Calvano, J. E., Hahm, S. J., Coyle, S. M., Corbett, S. A., Calvano, S. E., and Lowry, S. F. (2002) J. Infect. Dis. 186, 1522-1525
26. Randow, F., and Seed, B. (2001) Nat. Cell Biol. 3, 891-896
27. Wakabayashi, Y., Kobayashi, M., Akashi-Takamura, S., Tanimura, N., Konno, K., Takahashi, K., Ishii, T., Mizutani, T., Iba, H., Kouro, T., Takaki, S., Takatsu, K., Oda, Y., Ishihama, Y., Saitoh, S., and Miyake, K. (2006) J. Immunol. 177, 1772-1779
28. Konno, K., Wakabayashi, Y., Akashi-Takamura, S., Ishii, T., Kobayashi, M., Takahashi, K., Kusumoto, Y., Saitoh, S., Yoshizawa, Y., and Miyake, K. (2006) Biochem. Biophys. Res. Commun. 339, 1076-1082
29. Nishitani, C., Mitsuzawa, H., Sano, H., Shimizu, T., Matsushima, N., and Kuroki, Y. (2006) J. Biol. Chem. 281, 38322-38329
30. Akashi, S., Shimazu, R., Ogata, H., Nagai, Y., Takeda, K., Kimoto, M., and Miyake, K. (2000) J. Immunol. 164, 3471-3475
31. Espevik, T., Latz, E., Lien, E., Monks, B., and Golenbock, D. T. (2003) Scand. J. Infect. Dis. 35, 660-664
32. Muta, T., and Takeshige, K. (2001) Eur. J. Biochem. 268, 4580-4589
33. da Silva Correia, J., and Ulevitch, R. J. (2002) J. Biol. Chem. 277, 1845-1854