Site-specific analysis of UV-induced cyclobutane pyrimidine dimers in nucleotide excision repair-proficient and -deficient hamster cells: Lack of correlation with mutational spectra

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 663, Issue 1-2, 2009, Pages 7-14

  Vreeswijk, Maaike P G ^a   Meijers, Caro M ^a   Giphart Gassler, Micheline ^a   Vrieling, Harry ^a   van Zeeland, Albert A ^a   Mullenders, Leon H F ^a   Loenen, Wil A M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

CPD; DNA repair; Hamster hprt gene; LMPCR; UV induced mutations

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; PYRIMIDINE DIMER;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; EXCISION REPAIR; EXON; GENE MUTATION; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS; ULTRAVIOLET RADIATION;

ANIMALS; BASE SEQUENCE; CHO CELLS; CRICETINAE; CRICETULUS; DNA REPAIR; EXONS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MOLECULAR SEQUENCE DATA; MUTATION; PYRIMIDINE DIMERS; ULTRAVIOLET RAYS;

CRICETINAE;

EID: 63549105991     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2008.12.007     Document Type: Article

References (49)

1. Jans J., Schul W., Sert Y.G., Rijksen Y., Rebel H., Eker A.P., Nakajima S., van Steeg H., de Gruijl F.R., Yasui A., Hoeijmakers J.H., and van der Horst G.T. Powerful skin cancer protection by a CPD-photolyase transgene. Curr. Biol. 15 (2005) 105-115
2. Pfeifer G.P., You Y.H., and Besaratinia A. Mutations induced by ultraviolet light. Mutat. Res. 571 (2005) 19-31
3. de Lima-Bessa K.M., Armelini M.G., Chigancas V., Jacysyn J.F., marante-Mendes G.P., Sarasin A., and Menck C.F. CPDs and 6-4PPs play different roles in UV-induced cell death in normal and NER-deficient human cells. DNA Repair (Amst.) 7 (2008) 303-312
4. You Y.H., Lee D.H., Yoon J.H., Nakajima S., Yasui A., and Pfeifer G.P. Cyclobutane pyrimidine dimers are responsible for the vast majority of mutations induced by UVB irradiation in mammalian cells. J. Biol. Chem. 276 (2001) 44688-44694
5. Lo H.L., Nakajima S., Ma L., Walter B., Yasui A., Ethell D.W., and Owen L.B. Differential biologic effects of CPD and 6-4PP UV-induced DNA damage on the induction of apoptosis and cell-cycle arrest. BMC Cancer 5 (2005) 135
6. Friedberg E.C. Out of the shadows and into the light: the emergence of DNA repair. Trends Biochem. Sci. 20 (1995) 381
7. Cleaver J.E. Cancer in xeroderma pigmentosum and related disorders of DNA repair. Nat. Rev. Cancer 5 (2005) 564-573
8. Laine J.P., and Egly J.M. When transcription and repair meet: a complex system. Trends Genet. 22 (2006) 430-436
9. Mellon I., Spivak G., and Hanawalt P.C. Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene. Cell 51 (1987) 241-249
10. Venema J., van Hoffen A., Karcagi V., Natarajan A.T., van Zeeland A.A., and Mullenders L.H. Xeroderma pigmentosum complementation group C cells remove pyrimidine dimers selectively from the transcribed strand of active genes. Mol. Cell Biol. 11 (1991) 4128-4134
11. van Zeeland A.A., Vreeswijk M.P., de Gruijl F.R., van Kranen H.J., Vrieling H., and Mullenders L.F. Transcription-coupled repair: impact on UV-induced mutagenesis in cultured rodent cells and mouse skin tumors. Mutat. Res. 577 (2005) 170-178
12. Sarasin A., and Stary A. New insights for understanding the transcription-coupled repair pathway. DNA Repair (Amst.) 6 (2007) 265-269
13. Jansen J.G., and de Wind N. Biological functions of translesion synthesis proteins in vertebrates. DNA Repair (Amst.) 2 (2003) 1075-1085
14. Plosky B.S., and Woodgate R. Switching from high-fidelity replicases to low-fidelity lesion-bypass polymerases. Curr. Opin. Genet. Dev. 14 (2004) 113-119
15. Friedberg E.C., Lehmann A.R., and Fuchs R.P. Trading places: how do DNA polymerases switch during translesion DNA synthesis?. Mol. Cell 18 (2005) 499-505
16. Lehmann A.R., Niimi A., Ogi T., Brown S., Sabbioneda S., Wing J.F., Kannouche P.L., and Green C.M. Translesion synthesis: Y-family polymerases and the polymerase switch. DNA Repair (Amst.) 6 (2007) 891-899
17. Mitchell D.L., Zdzienicka M.Z., van Zeeland A.A., and Nairn R.S. Intermediate (6-4) photoproduct repair in Chinese hamster V79 mutant V-H1 correlates with intermediate levels of DNA incision and repair replication. Mutat. Res. 226 (1989) 43-47
18. Vrieling H., van Rooijen M.L., Groen N.A., Zdzienicka M.Z., Simons J.W., Lohman P.H., and van Zeeland A.A. DNA strand specificity for UV-induced mutations in mammalian cells. Mol. Cell Biol. 9 (1989) 1277-1283
19. Vrieling H., Venema J., van Rooyen M.L., van Hoffen A., Menichini P., Zdzienicka M.Z., Simons J.W., Mullenders L.H., and van Zeeland A.A. Strand specificity for UV-induced DNA repair and mutations in the Chinese hamster HPRT gene. Nucleic Acids Res. 19 (1991) 2411-2415
20. Menichini P., Vrieling H., and van Zeeland A.A. Strand-specific mutation spectra in repair-proficient and repair-deficient hamster cells. Mutat. Res. 251 (1991) 143-155
21. Vrieling H., Zhang L.H., van Zeeland A.A., and Zdzienicka M.Z. UV-induced hprt mutations in a UV-sensitive hamster cell line from complementation group 3 are biased towards the transcribed strand. Mutat. Res. 274 (1992) 147-155
22. Tornaletti S., Rozek D., and Pfeifer G.P. The distribution of UV photoproducts along the human p53 gene and its relation to mutations in skin cancer. Oncogene 8 (1993) 2051-2057
23. Tornaletti S., and Pfeifer G.P. Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer. Science 263 (1994) 1436-1438
24. Wei D., Maher V.M., and McCormick J.J. Site-specific rates of excision repair of benzo[a]pyrene diol epoxide adducts in the hypoxanthine phosphoribosyltransferase gene of human fibroblasts: correlation with mutation spectra. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 2204-2208
25. Rochette P.J., Therrien J.P., Drouin R., Perdiz D., Bastien N., Drobetsky E.A., and Sage E. UVA-induced cyclobutane pyrimidine dimers form predominantly at thymine-thymine dipyrimidines and correlate with the mutation spectrum in rodent cells. Nucleic Acids Res. 31 (2003) 2786-2794
26. Zdzienicka M.Z., van der Schans G.P., Westerveld A., van Zeeland A.A., and Simons J.W. Phenotypic heterogeneity within the first complementation group of UV-sensitive mutants of Chinese hamster cell lines. Mutat. Res. 193 (1988) 31-41
27. Eker A.P., Kooiman P., Hessels J.K., and Yasui A. DNA photoreactivating enzyme from the cyanobacterium Anacystis nidulans. J. Biol. Chem. 265 (1990) 8009-8015
28. Pfeifer G.P., Drouin R., and Holmquist G.P. Detection of DNA adducts at the DNA sequence level by ligation-mediated PCR. Mutat. Res. 288 (1993) 39-46
29. Pfeifer G.P., Drouin R., Riggs A.D., and Holmquist G.P. Binding of transcription factors creates hot spots for UV photoproducts in vivo. Mol. Cell Biol. 12 (1992) 1798-1804
30. Maxam A.M., and Gilbert W. Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol. 65 (1980) 499-560
31. Ruven H.J., Seelen C.M., Lohman P.H., Mullenders L.H., and van Zeeland A.A. Efficient synthesis of 32P-labeled single-stranded DNA probes using linear PCR; application of the method for analysis of strand-specific DNA repair. Mutat. Res. 315 (1994) 189-195
32. Cariello N.F., and Skopek T.R. In vivo mutation at the human HPRT locus. Trends Genet. 9 (1993) 322-326
33. Pfeifer G.P. Mutagenesis at methylated CpG sequences. Curr. Top. Microbiol. Immunol. 301 (2006) 259-281
34. Ikehata H., and Ono T. Significance of CpG methylation for solar UV-induced mutagenesis and carcinogenesis in skin. Photochem. Photobiol. 83 (2007) 196-204
35. Mitchell D.L., Jen J., and Cleaver J.E. Sequence specificity of cyclobutane pyrimidine dimers in DNA treated with solar (ultraviolet B) radiation. Nucleic Acids Res. 20 (1992) 225-229
36. Setlow R.B., and Carrier W.L. Pyrimidine dimers in ultraviolet-irradiated DNA's. J. Mol. Biol. 17 (1966) 237-254
37. van Hoffen A., Venema J., Meschini R., van Zeeland A.A., and Mullenders L.H. Transcription-coupled repair removes both cyclobutane pyrimidine dimers and 6-4 photoproducts with equal efficiency and in a sequential way from transcribed DNA in xeroderma pigmentosum group C fibroblasts. EMBO J. 14 (1995) 360-367
38. Vreeswijk M.P., van Hoffen A., Westland B.E., Vrieling H., van Zeeland A.A., and Mullenders L.H. Analysis of repair of cyclobutane pyrimidine dimers and pyrimidine 6-4 pyrimidone photoproducts in transcriptionally active and inactive genes in Chinese hamster cells. J. Biol. Chem. 269 (1994) 31858-31863
39. Drobetsky E.A., Grosovsky A.J., and Glickman B.W. The specificity of UV-induced mutations at an endogenous locus in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 84 (1987) 9103-9107
40. McGregor W.G., Chen R.H., Lukash L., Maher V.M., and McCormick J.J. Cell cycle-dependent strand bias for UV-induced mutations in the transcribed strand of excision repair-proficient human fibroblasts but not in repair-deficient cells. Mol. Cell Biol. 11 (1991) 1927-1934
41. Drobetsky E.A., and Sage E. UV-induced G:C → A:T transitions at the APRT locus of Chinese hamster ovary cells cluster at frequently damaged 5′-TCC-3′ sequences. Mutat. Res. 289 (1993) 131-138
42. Zheng Y., Pao A., Adair G.M., and Tang M. Cyclobutane pyrimidine dimers and bulky chemical DNA adducts are efficiently repaired in both strands of either a transcriptionally active or promoter-deleted APRT gene. J. Biol. Chem. 276 (2001) 16786-16796
43. Cohen S.M., Brylawski B.P., Cordeiro-Stone M., and Kaufman D.G. Mapping of an origin of DNA replication near the transcriptional promoter of the human HPRT gene. J. Cell Biochem. 85 (2002) 346-356
44. Sage E., Lamolet B., Brulay E., Moustacchi E., Chteauneuf A., and Drobetsky E.A. Mutagenic specificity of solar UV light in nucleotide excision repair-deficient rodent cells. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 176-180
45. Giglia G., Dumaz N., Drougard C., Avril M.F., ya-Grosjean L., and Sarasin A. p53 mutations in skin and internal tumors of xeroderma pigmentosum patients belonging to the complementation group C. Cancer Res. 58 (1998) 4402-4409
46. Dumaz N., Drougard C., Sarasin A., and ya-Grosjean L. Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 10529-10533
47. Prakash S., Johnson R.E., and Prakash L. Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function. Ann. Rev. Biochem. 74 (2005) 317-353
48. Tu Y., Dammann R., and Pfeifer G.P. Sequence and time-dependent deamination of cytosine bases in UVB-induced cyclobutane pyrimidine dimers in vivo. J. Mol. Biol. 284 (1998) 297-311
49. Hendriks G., Calleja F., Vrieling H., Mullenders L.H., Jansen J.G., and de Wind N. Gene transcription increases DNA damage-induced mutagenesis in mammalian stem cells. DNA Repair (Amst.) 7 (2008) 1330-1339