Gene transcription increases DNA damage-induced mutagenesis in mammalian stem cells

DNA Repair

Volumn 7, Issue 8, 2008, Pages 1330-1339

  Hendriks, Giel ^a   Calléja, Fabienne ^a   Vrieling, Harry ^a   Mullenders, Leon H F ^a   Jansen, Jacob G ^a   de Wind, Niels ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Intragenic deletions; LOH; Mutagenesis; Stem cells; Transcription

Indexed keywords

DIHYDROXYBENZO[A]PYRENE OXIDE; DNA; TETRACYCLINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; EMBRYONIC STEM CELL; GENE; GENE DELETION; GENE MUTATION; GENETIC TRANSCRIPTION; HETEROZYGOSITY LOSS; HPRT GENE; NONHUMAN; PRIORITY JOURNAL; ULTRAVIOLET RADIATION;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ANIMALS; DNA DAMAGE; EMBRYONIC STEM CELLS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LOSS OF HETEROZYGOSITY; MICE; MUTAGENESIS; RATS; TRANSCRIPTION, GENETIC; ULTRAVIOLET RAYS;

MAMMALIA;

EID: 46649094154     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2008.04.015     Document Type: Article

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