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Volumn 203, Issue 4, 2009, Pages 693-702

Hyperphagia and increased meal size are responsible for weight gain in rats treated sub-chronically with olanzapine

Author keywords

Antipsychotic; Appetite; Hyperphagia; Hypothalamus; Meal size; mRNA; Olanzapine; Pair feeding; Rat; Weight gain

Indexed keywords

MELANIN CONCENTRATING HORMONE; MESSENGER RNA; NEUROPEPTIDE Y; OLANZAPINE; OREXIN; PROOPIOMELANOCORTIN;

EID: 63449100443     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-008-1415-1     Document Type: Article
Times cited : (60)

References (54)
  • 1
    • 0041672505 scopus 로고    scopus 로고
    • The atypical antipsychotics risperidone, clozapine and olanzapine differ regarding their sedative potency in rats
    • A Ahnaou AA Megens WH Drinkenburg 2003 The atypical antipsychotics risperidone, clozapine and olanzapine differ regarding their sedative potency in rats Neuropsychobiology 48 47 54
    • (2003) Neuropsychobiology , vol.48 , pp. 47-54
    • Ahnaou, A.1    Megens, A.A.2    Drinkenburg, W.H.3
  • 6
    • 0035024729 scopus 로고    scopus 로고
    • Factors influencing acute weight change in patients with schizophrenia treated with olanzapine, haloperidol, or risperidone
    • BR Basson BJ Kinon CC Taylor KA Szymanski JA Gilmore GD Tollefson 2001 Factors influencing acute weight change in patients with schizophrenia treated with olanzapine, haloperidol, or risperidone J Clin Psychiatry 62 231 238
    • (2001) J Clin Psychiatry , vol.62 , pp. 231-238
    • Basson, B.R.1    Kinon, B.J.2    Taylor, C.C.3    Szymanski, K.A.4    Gilmore, J.A.5    Tollefson, G.D.6
  • 7
    • 0031736947 scopus 로고    scopus 로고
    • Weight changes during clozapine treatment
    • D Briffa T Meehan 1998 Weight changes during clozapine treatment Aust N Z J Psychiatry 32 718 721
    • (1998) Aust N Z J Psychiatry , vol.32 , pp. 718-721
    • Briffa, D.1    Meehan, T.2
  • 9
    • 34548542060 scopus 로고    scopus 로고
    • Effect of chronic infusion of olanzapine and clozapine on food intake and body weight gain in male and female rats
    • S Choi B DiSilvio J Unangst JD Fernstrom 2007 Effect of chronic infusion of olanzapine and clozapine on food intake and body weight gain in male and female rats Life Sci 81 1024 1030
    • (2007) Life Sci , vol.81 , pp. 1024-1030
    • Choi, S.1    Disilvio, B.2    Unangst, J.3    Fernstrom, J.D.4
  • 10
    • 0033955690 scopus 로고    scopus 로고
    • Meal patterning in rodents: Psychopharmacological and neuroanatomical studies
    • PG Clifton 2000 Meal patterning in rodents: psychopharmacological and neuroanatomical studies Neurosci Biobehav Rev 24 213 222
    • (2000) Neurosci Biobehav Rev , vol.24 , pp. 213-222
    • Clifton, P.G.1
  • 11
    • 0025921566 scopus 로고
    • Effects of dopamine D1 and dopamine D2 antagonists on the free feeding and drinking patterns of rats
    • PG Clifton IN Rusk SJ Cooper 1991 Effects of dopamine D1 and dopamine D2 antagonists on the free feeding and drinking patterns of rats Behav Neurosci 105 272 281
    • (1991) Behav Neurosci , vol.105 , pp. 272-281
    • Clifton, P.G.1    Rusk, I.N.2    Cooper, S.J.3
  • 12
    • 0033778106 scopus 로고    scopus 로고
    • Similarities in the action of Ro 60-0175, a 5-HT2Creceptor agonist, and d-fenfluramine on feeding patterns in the rat
    • PG Clifton MD Lee CT Dourish 2000 Similarities in the action of Ro 60-0175, a 5-HT2Creceptor agonist, and d-fenfluramine on feeding patterns in the rat Psychopharmacology 152 256 267
    • (2000) Psychopharmacology , vol.152 , pp. 256-267
    • Clifton, P.G.1    Lee, M.D.2    Dourish, C.T.3
  • 14
    • 34447575781 scopus 로고    scopus 로고
    • Effects of olanzapine in male rats: Enhanced adiposity in the absence of hyperphagia, weight gain or metabolic abnormalities
    • GD Cooper LC Pickavance JP Wilding JA Harrold JC Halford AJ Goudie 2007 Effects of olanzapine in male rats: enhanced adiposity in the absence of hyperphagia, weight gain or metabolic abnormalities J Psychopharmacol 21 405 413
    • (2007) J Psychopharmacol , vol.21 , pp. 405-413
    • Cooper, G.D.1    Pickavance, L.C.2    Wilding, J.P.3    Harrold, J.A.4    Halford, J.C.5    Goudie, A.J.6
  • 15
    • 40549098407 scopus 로고    scopus 로고
    • Comparative effects of olanzapine and ziprasidone on hypophagia induced by enhanced histamine neurotransmission in the rat
    • N Davoodi M Kalinichev PG Clifton 2008 Comparative effects of olanzapine and ziprasidone on hypophagia induced by enhanced histamine neurotransmission in the rat Behav Pharmacol 19 121 128
    • (2008) Behav Pharmacol , vol.19 , pp. 121-128
    • Davoodi, N.1    Kalinichev, M.2    Clifton, P.G.3
  • 16
    • 0032940785 scopus 로고    scopus 로고
    • The effect of the orexins on food intake: Comparison with neuropeptide Y, melanin-concentrating hormone and galanin
    • CM Edwards S Abusnana D Sunter KG Murphy MA Ghatei SR Bloom 1999 The effect of the orexins on food intake: comparison with neuropeptide Y, melanin-concentrating hormone and galanin J Endocrinol 160 R7 R12
    • (1999) J Endocrinol , vol.160
    • Edwards, C.M.1    Abusnana, S.2    Sunter, D.3    Murphy, K.G.4    Ghatei, M.A.5    Bloom, S.R.6
  • 17
    • 0036703780 scopus 로고    scopus 로고
    • Differential activation of orexin neurons by antipsychotic drugs associated with weight gain
    • J Fadel M Bubser AY Deutch 2002 Differential activation of orexin neurons by antipsychotic drugs associated with weight gain J Neurosci 22 6742 6746
    • (2002) J Neurosci , vol.22 , pp. 6742-6746
    • Fadel, J.1    Bubser, M.2    Deutch, A.Y.3
  • 18
    • 3242740983 scopus 로고    scopus 로고
    • Effects of the atypical antipsychotic olanzapine on reproductive function and weight gain in female rats
    • MJ Fell KM Marshall J Williams JC Neill 2004 Effects of the atypical antipsychotic olanzapine on reproductive function and weight gain in female rats J Psychopharmacol 18 149 155
    • (2004) J Psychopharmacol , vol.18 , pp. 149-155
    • Fell, M.J.1    Marshall, K.M.2    Williams, J.3    Neill, J.C.4
  • 19
    • 26844445669 scopus 로고    scopus 로고
    • Effects of sub-chronic antipsychotic drug treatment on body weight and reproductive function in juvenile female rats
    • MJ Fell JC Neill C Rao KM Marshall 2005 Effects of sub-chronic antipsychotic drug treatment on body weight and reproductive function in juvenile female rats Psychopharmacology (Berl) 182 499 507
    • (2005) Psychopharmacology (Berl) , vol.182 , pp. 499-507
    • Fell, M.J.1    Neill, J.C.2    Rao, C.3    Marshall, K.M.4
  • 22
    • 0036904224 scopus 로고    scopus 로고
    • Characterization of olanzapine-induced weight gain in rats
    • AJ Goudie JA Smith JC Halford 2002 Characterization of olanzapine-induced weight gain in rats J Psychopharmacol 16 291 296
    • (2002) J Psychopharmacol , vol.16 , pp. 291-296
    • Goudie, A.J.1    Smith, J.A.2    Halford, J.C.3
  • 24
    • 0038693732 scopus 로고    scopus 로고
    • Effects of clozapine, olanzapine and haloperidol on the microstructure of ingestive behaviour in the rat
    • AW Hartfield NA Moore PG Clifton 2003 Effects of clozapine, olanzapine and haloperidol on the microstructure of ingestive behaviour in the rat Psychopharmacology (Berl) 167 115 122
    • (2003) Psychopharmacology (Berl) , vol.167 , pp. 115-122
    • Hartfield, A.W.1    Moore, N.A.2    Clifton, P.G.3
  • 25
    • 33747361348 scopus 로고    scopus 로고
    • Effects of atypical antipsychotic drugs on intralipid intake and cocaine-induced hyperactivity in rats
    • AW Hartfield NA Moore PG Clifton 2006 Effects of atypical antipsychotic drugs on intralipid intake and cocaine-induced hyperactivity in rats Neuropsychopharmacology 31 1938 1945
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1938-1945
    • Hartfield, A.W.1    Moore, N.A.2    Clifton, P.G.3
  • 26
    • 33646428953 scopus 로고    scopus 로고
    • Neuropeptide y mRNA expression levels following chronic olanzapine, clozapine and haloperidol administration in rats
    • XF Huang C Deng K Zavitsanou 2006 Neuropeptide Y mRNA expression levels following chronic olanzapine, clozapine and haloperidol administration in rats Neuropeptides 40 213 219
    • (2006) Neuropeptides , vol.40 , pp. 213-219
    • Huang, X.F.1    Deng, C.2    Zavitsanou, K.3
  • 27
    • 26844446471 scopus 로고    scopus 로고
    • Characterisation of olanzapine-induced weight gain and effect of aripiprazole vs olanzapine on body weight and prolactin secretion in female rats
    • M Kalinichev C Rourke AJ Daniels MK Grizzle CS Britt DM Ignar DN Jones 2005 Characterisation of olanzapine-induced weight gain and effect of aripiprazole vs olanzapine on body weight and prolactin secretion in female rats Psychopharmacology (Berl) 182 220 231
    • (2005) Psychopharmacology (Berl) , vol.182 , pp. 220-231
    • Kalinichev, M.1    Rourke, C.2    Daniels, A.J.3    Grizzle, M.K.4    Britt, C.S.5    Ignar, D.M.6    Jones, D.N.7
  • 28
    • 33645721657 scopus 로고    scopus 로고
    • Body weights and plasma prolactin levels in female rats treated subchronically with ziprasidone versus olanzapine
    • M Kalinichev C Rourke DN Jones 2006 Body weights and plasma prolactin levels in female rats treated subchronically with ziprasidone versus olanzapine Behav Pharmacol 17 289 292
    • (2006) Behav Pharmacol , vol.17 , pp. 289-292
    • Kalinichev, M.1    Rourke, C.2    Jones, D.N.3
  • 30
    • 33745025286 scopus 로고    scopus 로고
    • Clozapine, but not haloperidol, increases neuropeptide y neuronal expression in the rat hypothalamus
    • SL Kirk M Cahir GP Reynolds 2006 Clozapine, but not haloperidol, increases neuropeptide Y neuronal expression in the rat hypothalamus J Psychopharmacol 20 577 579
    • (2006) J Psychopharmacol , vol.20 , pp. 577-579
    • Kirk, S.L.1    Cahir, M.2    Reynolds, G.P.3
  • 32
    • 0041328018 scopus 로고    scopus 로고
    • Objective and subjective efficacy as well as tolerability of olanzapine in the acute treatment of 120 patients with schizophrenia spectrum disorders
    • M Lambert R Holzbach S Moritz N Postel M Krausz D Naber 2003 Objective and subjective efficacy as well as tolerability of olanzapine in the acute treatment of 120 patients with schizophrenia spectrum disorders Int Clin Psychopharmacol 18 251 260
    • (2003) Int Clin Psychopharmacol , vol.18 , pp. 251-260
    • Lambert, M.1    Holzbach, R.2    Moritz, S.3    Postel, N.4    Krausz, M.5    Naber, D.6
  • 33
    • 0026534847 scopus 로고
    • Partial reversal of fluoxetine anorexia by the 5-HT antagonist metergoline
    • MD Lee PG Clifton 1992 Partial reversal of fluoxetine anorexia by the 5-HT antagonist metergoline Psychopharmacology (Berl) 107 359 364
    • (1992) Psychopharmacology (Berl) , vol.107 , pp. 359-364
    • Lee, M.D.1    Clifton, P.G.2
  • 34
    • 0037006054 scopus 로고    scopus 로고
    • Meal patterns of free feeding rats treated with clozapine, olanzapine, or haloperidol
    • MD Lee PG Clifton 2002 Meal patterns of free feeding rats treated with clozapine, olanzapine, or haloperidol Pharmacol Biochem Behav 71 147 154
    • (2002) Pharmacol Biochem Behav , vol.71 , pp. 147-154
    • Lee, M.D.1    Clifton, P.G.2
  • 35
    • 0021732102 scopus 로고
    • Neuropeptide Y: A potent inducer of consummatory behavior in rats
    • AS Levine JE Morley 1984 Neuropeptide Y: a potent inducer of consummatory behavior in rats Peptides 5 1025 1029
    • (1984) Peptides , vol.5 , pp. 1025-1029
    • Levine, A.S.1    Morley, J.E.2
  • 36
    • 0022544444 scopus 로고
    • The role of dopamine in the control of neuropeptide y neurons in the rat arcuate nucleus
    • S Li G Pelletier 1986 The role of dopamine in the control of neuropeptide Y neurons in the rat arcuate nucleus Neurosci Lett 69 74 77
    • (1986) Neurosci Lett , vol.69 , pp. 74-77
    • Li, S.1    Pelletier, G.2
  • 40
    • 0029970781 scopus 로고    scopus 로고
    • Long-term treatment with chlorpromazine and haloperidol but not with sulpiride and clozapine markedly elevates neuropeptide Y-like immunoreactivity in the rat hypothalamus
    • E Obuchowicz 1996 Long-term treatment with chlorpromazine and haloperidol but not with sulpiride and clozapine markedly elevates neuropeptide Y-like immunoreactivity in the rat hypothalamus Neuropeptides 30 471 478
    • (1996) Neuropeptides , vol.30 , pp. 471-478
    • Obuchowicz, E.1
  • 41
    • 29644444481 scopus 로고    scopus 로고
    • Influence of chronic treatment with olanzapine, clozapine and scopolamine on performance of a learned 8-arm radial maze task in rats
    • A Ortega-Alvaro J Gibert-Rahola JA Mico 2006 Influence of chronic treatment with olanzapine, clozapine and scopolamine on performance of a learned 8-arm radial maze task in rats Prog Neuropsychopharmacol Biol Psychiatry 30 104 111
    • (2006) Prog Neuropsychopharmacol Biol Psychiatry , vol.30 , pp. 104-111
    • Ortega-Alvaro, A.1    Gibert-Rahola, J.2    Mico, J.A.3
  • 42
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • MW Pfaffl 2001 A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res 29 e45
    • (2001) Nucleic Acids Res , vol.29 , pp. 45
    • Pfaffl, M.W.1
  • 43
    • 0037621479 scopus 로고    scopus 로고
    • Chronic treatment with antipsychotics in rats as a model for antipsychotic-induced weight gain in human
    • B Pouzet T Mow M Kreilgaard S Velschow 2003 Chronic treatment with antipsychotics in rats as a model for antipsychotic-induced weight gain in human Pharmacol Biochem Behav 75 133 140
    • (2003) Pharmacol Biochem Behav , vol.75 , pp. 133-140
    • Pouzet, B.1    Mow, T.2    Kreilgaard, M.3    Velschow, S.4
  • 44
    • 0346731075 scopus 로고    scopus 로고
    • Clozapine's effects on body weight and resting metabolic rate: A case series
    • RM Procyshyn A Chau G Tse 2004 Clozapine's effects on body weight and resting metabolic rate: a case series Schizophr Res 66 159 162
    • (2004) Schizophr Res , vol.66 , pp. 159-162
    • Procyshyn, R.M.1    Chau, A.2    Tse, G.3
  • 46
    • 0030014954 scopus 로고    scopus 로고
    • Different behavioral effects of haloperidol, clozapine and thioridazine in a concurrent lever pressing and feeding procedure
    • JD Salamone MS Cousins C Maio M Champion T Turski J Kovach 1996 Different behavioral effects of haloperidol, clozapine and thioridazine in a concurrent lever pressing and feeding procedure Psychopharmacology (Berl) 125 105 112
    • (1996) Psychopharmacology (Berl) , vol.125 , pp. 105-112
    • Salamone, J.D.1    Cousins, M.S.2    Maio, C.3    Champion, M.4    Turski, T.5    Kovach, J.6
  • 47
    • 34447528738 scopus 로고    scopus 로고
    • Antipsychotic medication, sedation and mental clouding: An observational study of psychiatric consultations
    • C Seale R Chaplin P Lelliott A Quirk 2007 Antipsychotic medication, sedation and mental clouding: an observational study of psychiatric consultations Soc Sci Med 65 698 711
    • (2007) Soc Sci Med , vol.65 , pp. 698-711
    • Seale, C.1    Chaplin, R.2    Lelliott, P.3    Quirk, A.4
  • 48
    • 33746641002 scopus 로고    scopus 로고
    • Energy expenditure and physical activity in clozapine use: Implications for weight management
    • JK Sharpe TJ Stedman NM Byrne C Wishart AP Hills 2006 Energy expenditure and physical activity in clozapine use: implications for weight management Aust N Z J Psychiatry 40 810 814
    • (2006) Aust N Z J Psychiatry , vol.40 , pp. 810-814
    • Sharpe, J.K.1    Stedman, T.J.2    Byrne, N.M.3    Wishart, C.4    Hills, A.P.5
  • 49
    • 0036205425 scopus 로고    scopus 로고
    • The atypical antipsychotic olanzapine enhances ingestive behaviour in the rat: A preliminary study
    • Z Thornton-Jones JC Neill GP Reynolds 2002 The atypical antipsychotic olanzapine enhances ingestive behaviour in the rat: a preliminary study J Psychopharmacol 16 35 37
    • (2002) J Psychopharmacol , vol.16 , pp. 35-37
    • Thornton-Jones, Z.1    Neill, J.C.2    Reynolds, G.P.3
  • 51
    • 33947274677 scopus 로고    scopus 로고
    • Atypical antipsychotic drugs directly impair insulin action in adipocytes: Effects on glucose transport, lipogenesis, and antilipolysis
    • HS Vestri L Maianu DR Moellering WT Garvey 2007 Atypical antipsychotic drugs directly impair insulin action in adipocytes: effects on glucose transport, lipogenesis, and antilipolysis Neuropsychopharmacology 32 765 772
    • (2007) Neuropsychopharmacology , vol.32 , pp. 765-772
    • Vestri, H.S.1    Maianu, L.2    Moellering, D.R.3    Garvey, W.T.4
  • 54
    • 0347596648 scopus 로고    scopus 로고
    • Obesity as a risk factor for antipsychotic noncompliance
    • PJ Weiden JA Mackell DD McDonnell 2004 Obesity as a risk factor for antipsychotic noncompliance Schizophr Res 66 51 57
    • (2004) Schizophr Res , vol.66 , pp. 51-57
    • Weiden, P.J.1    MacKell, J.A.2


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