The NR2B-selective N-methyl-D-aspartate receptor antagonist Ro 25-6981 [(±)-(R*,S*)-α-(4-hydroxyphenyl)-β-methyl-4- (phenylmethyl)-1-piperidine propanol] potentiates the effect of nicotine on locomotor activity and dopamine release in the nucleus accumbens

Journal of Pharmacology and Experimental Therapeutics

Volumn 311, Issue 2, 2004, Pages 560-567

  Kosowski, Alexander R ^a   Liljequist, Sture ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 4 METHYL 5 PHOSPHONO 3 PENTENOIC ACID ETHYL ESTER; 4 BENZYL ALPHA (4 HYDROXYPHENYL) BETA METHYL 1 PIPERIDINEPROPANOL; 4 PHOSPHONOMETHYLPIPECOLIC ACID; ALPHA (4 HYDROXYPHENYL) BETA METHYL 4 (PHENYLMETHYL) 1 PIPERIDINE PROPANOL; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NICOTINE; NICOTINE TARTRATE; PROTEIN NR2; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; CONTROLLED STUDY; DOPAMINE RELEASE; DOSE RESPONSE; DRUG EFFECT; DRUG MEGADOSE; DRUG POTENTIATION; DRUG RECEPTOR BINDING; IN VIVO STUDY; LIMBIC CORTEX; LOCOMOTION; LOW DRUG DOSE; MALE; MAXIMUM ALLOWABLE CONCENTRATION; MICRODIALYSIS; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; STATISTICAL SIGNIFICANCE; TOBACCO DEPENDENCE;

2-AMINO-5-PHOSPHONOVALERATE; ANIMALS; DIZOCILPINE MALEATE; DOPAMINE; DRUG SYNERGISM; MALE; MICRODIALYSIS; MOTOR ACTIVITY; NICOTINE; NUCLEUS ACCUMBENS; PHENOLS; PIPERIDINES; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 6344229330     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.070235     Document Type: Article

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