Higher cytotoxicity of divalent antibody-toxins than monovalent antibody-toxins

Biochemical and Biophysical Research Communications

Volumn 382, Issue 1, 2009, Pages 15-20

  Won, JaeSeon ^a   Nam, PilWon ^a   Lee, YongChan ^a   Choe, MuHyeon ^a  

^a Korea University   (South Korea)

Author keywords

Avidity; Cytotoxicity; Divalent antibody toxin; Pseudomonas exotoxin A; Recombinant antibody refolding

Indexed keywords

DISULFIDE; IMMUNOGLOBULIN F(AB) FRAGMENT; PSEUDOMONAS EXOTOXIN;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TOXICITY TESTING; TOXIN ANALYSIS;

ADP RIBOSE TRANSFERASES; ANTIBODIES, BISPECIFIC; ANTIGENS, NEOPLASM; BACTERIAL TOXINS; CELL LINE, TUMOR; CYTOTOXICITY TESTS, IMMUNOLOGIC; CYTOTOXICITY, IMMUNOLOGIC; EXOTOXINS; HUMANS; IMMUNOTOXINS; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; VIRULENCE FACTORS;

PSEUDOMONAS EXOTOXIN;

EID: 63149196590     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.02.091     Document Type: Article

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