Increased refolding yield of disulfide bond bridged fab-toxin homodimers by the insertion of CH3 domains

Journal of Microbiology and Biotechnology

Volumn 16, Issue 7, 2006, Pages 1104-1110

  Song, Jeongwha ^a   Won, Jaeseon ^a   Lee, Yongchan ^a   Choe, Muhyeon ^a  

^a Korea University   (South Korea)

Author keywords

Antibody refolding; B3 antibody; Constant domain of heavy chain; Cytotoxicity; Dimer; Divalent antibody toxin; Pseudomonas exotoxin A.; Recombinant antibody toxin

Indexed keywords

BUTANE; CYSTEINE; HOMODIMER; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G1; IMMUNOTOXIN; IMMUNOTOXIN LMB2; METHYL GROUP; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY B3; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; COVALENT BOND; DIMERIZATION; DISULFIDE BOND; DRUG CYTOTOXICITY; DRUG FORMULATION; HUMAN; HUMAN CELL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE;

EID: 33746930529     PISSN: 10177825     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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