A divalent immunotoxin formed by the disulfide bond between hinge regions of fab domain

Bulletin of the Korean Chemical Society

Volumn 22, Issue 12, 2001, Pages 1361-1365

  Choi, SeongHyeok ^a   Kim, JiEun ^a   Lee, YongChan ^a   Jang, Young Ju ^b   Pastan, Ira ^c   Choe, MuHyeon ^a  

^a Korea University   (South Korea)

^b Ajou University School of Medicine   (South Korea)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

B3(FabH1) PE38 2; B3 antibody; Divalent immunotoxin; Pseudomonas exotoxin A, Antibody refolding

Indexed keywords

BACTERIAL TOXIN; CARBOHYDRATE ANTIGEN; CYSTEINE DERIVATIVE; CYTOTOXIC FACTOR; ELONGATION FACTOR 2; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G1; IMMUNOTOXIN; PSEUDOMONAS EXOTOXIN; PSEUDOMONAS EXOTOXIN A; SERINE; UNCLASSIFIED DRUG;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ARTICLE; CELL INCLUSION; CELL LINE; CYTOTOXICITY; DISULFIDE BOND; ESCHERICHIA COLI; EUKARYOTIC CELL; HUMAN; HUMAN CELL; PROTEIN DOMAIN; PROTEIN SYNTHESIS INHIBITION;

EID: 0035924897     PISSN: 02532964     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Pai, L. H.; Bookman, M. A.; Ozols, R. F.; Young, R. C.; Smith, J. W. II.; Longo, D. L.; Gould, B.; Frankel, A.; McClay, E. F.; Howell, S.; Reed, E.; Willingham, M. C.; FitzGerald, D. J.; Pastan, I. J. Clin. Oncol. 1991, 9, 1.
2. Schmiedl, A.; Breitling, F.; Dubel, S. Protein Engineering 2000, 13, 725.
3. Hudson, P. J.; Kortt, A. A. J. Immunol. Methods 1999, 231, 177.
4. Kreitman, R. J.; Wang, Q. C.; FitzGerald, D. J.; Pastan, I. Int. J. Cancer 1999, 81, 148.
5. Deonarain, M. P.; Epenetos, A. A. Br. J. Cancer 1998, 77, 537.
6. Baluna, R.; Coleman, E.; Jones, C.; Ghetie, V.; Vitetta, E. S. Exp. Cell. Res. 2000, 258, 417.
7. Buchner, J.; Brinkmann, U.; Pastan, I. Bio/Technology 1992, 10, 682.
8. Chowdhury, P. S.; Viner, J. L.; Beers, R.; Pastan, I. Proc. Natl. Acad. Sci. U S A 1998, 95, 669.
9. FitzGerald, D. J.; Waldmann, T. A.; Willingham, M. C.; Pastan, I. J. Clin. Invest. 1984, 74, 966.
10. Reiter, Y.; Kreitman, R. J.; Brinkmann, U.; Pastan, I. Int. J. Cancer 1994, 58, 142.
11. Theuer, C. P.; Pastan, I. Am. J. Surg. 1993, 166, 284.
12. Brinkmann, U.; Pai, L. H.; FitzGerald, D. J.; Willingham, M.; Pastan, I. Proc. Natl. Acad. Sci. USA 1991, 88, 8616.
13. Pai, L. H.; Batra, J. K.; FitzGerald, D. J.; Willingham, M. C.; Pastan, I. Cancer Res. 1992, 52, 3189.
14. Buchner, J.; Brinkmann, U.; Pastan, I. Biotechnology (NY) 1992, 10, 682.
15. Brinkmann, U.; Di Carlo, A.; Vasmatzis, G.; Kurochkina, N.; Beers, R.; Lee, B.; Pastan, I. J. Mol. Biol. 1997, 268, 107.
16. Reiter, Y.; Wright, A. F.; Tonge, D. W.; Pastan, I. Int. J. Cancer 1996, 67, 113.
17. Bera, T. K.; Viner, J.; Brinkmann, E.; Pastan, I. Cancer Res. 1999, 59, 4018.
18. Bera, T. K.; Pastan, I. Bioconjug. Chem. 1998, 9, 736.
19. Choe, M.; Webber, K. O.; Pastan, I. Cancer Res. 1994, 54, 3460.
20. Kreitman, R. J.; Hansen, H. J.; Jones, A. L.; FitzGerald, D. J.; Goldenberg, D. M.; Pastan, I. Cancer Res. 1993, 53, 819.
21. Debinski, W.; Pastan, I. Cancer Res. 1992, 52, 5379.
22. Kurucz, I.; Titus, J. A.; Jost, C. R.; Segal, D. M. Mol. Immunol. 1995, 32, 1443.
23. Lilie, H.; Schwarz, E.; Rudolph, R. Curr. Opin. Biotechnol. 1998, 9, 497.
24. Rajagopal, V.; Pastan, I.; Kreitman, R. J. Protein Eng. 1997, 10, 1453.
25. Burks, E. A.; Iverson, B. L. Biotechnol. Prog. 1995, 11, 112.
26. Suenaga, M.; Ohmae, H.; Tsuji, S.; Itoh, T.; Nishimura, O. Biotechnol. Appl. Biochem. 1998, 28, 119.
27. Johnson, D. L.; Middleton, S. A.; McMahon, F.; Barbone, F. P.; Kroon, D.; Tsao, E.; Lee, W. H.; Mulcahy, L. S.; Jolliffe, L. K. Protein Expr. Purif. 1996, 7, 104.
28. Buchner, J.; Pastan, I.; Brinkmann, U. Anal. Biochem. 1992, 205, 263.
29. Xu, Y. H.; Peng, S. F.; Jiang, W. L.; Zhu, Y.; Chandhary, V.; FitzGerald, D.; Pastan, I. Shih Yen Sheng Wu Hsueh Pao 1993, 26, 289.
30. Batra, J. K.; FitzGerald, D.; Gately, M.; Chaudhary, V. K.; Pastan, I. J. Biol. Chem. 1990, 265, 15198.
31. Martsev, S. P.; Kravchuk, Z. I.; Chumanevich, A. A.; Vlasov, A. P.; Dubnovitsky, A. P.; Bespalov, I. A.; Arosio, P.; Deyev, S. M. FEBS Lett. 1998, 441, 458.
32. Brinkmann, U.; Buchner, J.; Pastan, I. Proc. Natl. Acad. Sci. USA 1992, 89, 3075.
33. Pai, L. H.; Batra, J. K.; FitzGerald, D. J.; Willingham, M. C.; Pastan, I. Proc. Natl. Acad. Sci. USA 1991, 88, 3358.
34. Reiter, Y.; Pai, L. H.; Brinkmann, U.; Wang, Q. C.; Pastan, I. Cancer Res. 1994, 54, 2714.
35. Camera, L.; Kinuya, S.; Pai, L. H.; Garmestani, K.; Brechbiel, M. W.; Gansow, O. A.; Paik, C. H.; Pastan, I.; Carrasquillo, J. A. Cancer Res. 1993, 53, 2834.
36. Scherf, U.; Benhar, I.; Webber, K. O.; Pastan, I.; Brinkmann, U. Clin. Cancer Res. 1996, 2, 1523.