Molecular modeling studies and in vitro bioactivity evaluation of a set of novel 5-nitro-heterocyclic derivatives as anti-T. cruzi agents

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 7, 2009, Pages 2673-2679

  Paula, Fávero Reisdorfer ^a   Jorge, Salomão Dória ^a   Almeida, Leonardo Viana de ^a   Pasqualoto, Kerly Fernanda Mesquita ^a   Tavares, Leoberto Costa ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Bioactivity assay; Chagas disease; Molecular modeling; Nitrocompounds

Indexed keywords

ANTITRYPANOSOMAL AGENT; BENZIMIDAZOLE; HETEROCYCLIC COMPOUND; NIFUROXAZIDE; NIFUROXAZIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SENSITIVITY; LIPOPHILICITY; MOLECULAR MODEL; NONHUMAN; TRYPANOSOMA CRUZI;

ANIMALS; HYDROXYBENZOIC ACIDS; MODELS, MOLECULAR; NITROFURANS; NITROIMIDAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

EID: 63149169103     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.02.056     Document Type: Article

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