-
1
-
-
0029904694
-
Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes
-
Minegishi M., Tachibana K., Sato T., Iwata S., Nojima Y., and Morimoto C. Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes. J. Exp. Med. 184 (1996) 1365-1375
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1365-1375
-
-
Minegishi, M.1
Tachibana, K.2
Sato, T.3
Iwata, S.4
Nojima, Y.5
Morimoto, C.6
-
2
-
-
33645022769
-
HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells
-
Natarajan M., Stewart J.E., Golemis E.A., Pugacheva E.N., Alexandropoulos K., Cox B.D., Wang W., Grammer J.R., and Gladson C.L. HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells. Oncogene 25 (2006) 1721-1732
-
(2006)
Oncogene
, vol.25
, pp. 1721-1732
-
-
Natarajan, M.1
Stewart, J.E.2
Golemis, E.A.3
Pugacheva, E.N.4
Alexandropoulos, K.5
Cox, B.D.6
Wang, W.7
Grammer, J.R.8
Gladson, C.L.9
-
3
-
-
33745288277
-
Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene
-
Kim M., Gans J.D., Nogueira C., Wang A., Paik J.H., Feng B., Brennan C., Hahn W.C., Cordon-Cardo C., Wagner S.N., Flotte T.J., Duncan L.M., Granter S.R., and Chin L. Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene. Cell 125 (2006) 1269-1281
-
(2006)
Cell
, vol.125
, pp. 1269-1281
-
-
Kim, M.1
Gans, J.D.2
Nogueira, C.3
Wang, A.4
Paik, J.H.5
Feng, B.6
Brennan, C.7
Hahn, W.C.8
Cordon-Cardo, C.9
Wagner, S.N.10
Flotte, T.J.11
Duncan, L.M.12
Granter, S.R.13
Chin, L.14
-
4
-
-
0033214510
-
Tyrosine phosphorylation of Crk-associated substrate lymphocyte-type is a critical element in TCR- and beta 1 integrin-induced T lymphocyte migration
-
Ohashi Y., Iwata S., Kamiguchi K., and Morimoto C. Tyrosine phosphorylation of Crk-associated substrate lymphocyte-type is a critical element in TCR- and beta 1 integrin-induced T lymphocyte migration. J. Immunol. 163 (1999) 3727-3734
-
(1999)
J. Immunol.
, vol.163
, pp. 3727-3734
-
-
Ohashi, Y.1
Iwata, S.2
Kamiguchi, K.3
Morimoto, C.4
-
5
-
-
0035006726
-
Focal adhesion kinase regulates beta1 integrin-dependent T cell migration through an HEF1 effector pathway
-
van Seventer G.A., Salmen H.J., Law S.F., O'Neill G.M., Mullen M.M., Franz A.M., Kanner S.B., Golemis E.A., and van Seventer J.M. Focal adhesion kinase regulates beta1 integrin-dependent T cell migration through an HEF1 effector pathway. Eur. J. Immunol. 31 (2001) 1417-1427
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 1417-1427
-
-
van Seventer, G.A.1
Salmen, H.J.2
Law, S.F.3
O'Neill, G.M.4
Mullen, M.M.5
Franz, A.M.6
Kanner, S.B.7
Golemis, E.A.8
van Seventer, J.M.9
-
6
-
-
20044362183
-
HTLV-I Tax induces and associates with Crk-associated substrate lymphocyte type (Cas-L)
-
Iwata S., Souta-Kuribara A., Yamakawa A., Sasaki T., Shimizu T., Hosono O., Kawasaki H., Tanaka H., Dang N.H., Watanabe T., Arima N., and Morimoto C. HTLV-I Tax induces and associates with Crk-associated substrate lymphocyte type (Cas-L). Oncogene 24 (2005) 1262-1271
-
(2005)
Oncogene
, vol.24
, pp. 1262-1271
-
-
Iwata, S.1
Souta-Kuribara, A.2
Yamakawa, A.3
Sasaki, T.4
Shimizu, T.5
Hosono, O.6
Kawasaki, H.7
Tanaka, H.8
Dang, N.H.9
Watanabe, T.10
Arima, N.11
Morimoto, C.12
-
7
-
-
34547926839
-
LKB1 modulates lung cancer differentiation and metastasis
-
Ji H., Ramsey M.R., Hayes D.N., Fan C., McNamara K., Kozlowski P., Torrice C., Wu M.C., Shimamura T., Perera S.A., Liang M.C., Cai D., Naumov G.N., Bao L., Contreras C.M., Li D., Chen L., Krishnamurthy J., Koivunen J., Chirieac L.R., Padera R.F., Bronson R.T., Lindeman N.I., Christiani D.C., Lin X., Shapiro G.I., Janne P.A., Johnson B.E., Meyerson M., Kwiatkowski D.J., Castrillon D.H., Bardeesy N., Sharpless N.E., and Wong K.K. LKB1 modulates lung cancer differentiation and metastasis. Nature 448 (2007) 807-810
-
(2007)
Nature
, vol.448
, pp. 807-810
-
-
Ji, H.1
Ramsey, M.R.2
Hayes, D.N.3
Fan, C.4
McNamara, K.5
Kozlowski, P.6
Torrice, C.7
Wu, M.C.8
Shimamura, T.9
Perera, S.A.10
Liang, M.C.11
Cai, D.12
Naumov, G.N.13
Bao, L.14
Contreras, C.M.15
Li, D.16
Chen, L.17
Krishnamurthy, J.18
Koivunen, J.19
Chirieac, L.R.20
Padera, R.F.21
Bronson, R.T.22
Lindeman, N.I.23
Christiani, D.C.24
Lin, X.25
Shapiro, G.I.26
Janne, P.A.27
Johnson, B.E.28
Meyerson, M.29
Kwiatkowski, D.J.30
Castrillon, D.H.31
Bardeesy, N.32
Sharpless, N.E.33
Wong, K.K.34
more..
-
8
-
-
0031813880
-
Cell cycle-regulated processing of HEF1 to multiple protein forms differentially targeted to multiple subcellular compartments
-
Law S.F., Zhang Y.Z., Klein-Szanto A.J., and Golemis E.A. Cell cycle-regulated processing of HEF1 to multiple protein forms differentially targeted to multiple subcellular compartments. Mol. Cell Biol. 18 (1998) 3540-3551
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 3540-3551
-
-
Law, S.F.1
Zhang, Y.Z.2
Klein-Szanto, A.J.3
Golemis, E.A.4
-
9
-
-
33644868709
-
Deregulation of HEF1 impairs M-phase progression by disrupting the RhoA activation cycle
-
Dadke D., Jarnik M., Pugacheva E.N., Singh M.K., and Golemis E.A. Deregulation of HEF1 impairs M-phase progression by disrupting the RhoA activation cycle. Mol. Biol. Cell 17 (2006) 1204-1217
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 1204-1217
-
-
Dadke, D.1
Jarnik, M.2
Pugacheva, E.N.3
Singh, M.K.4
Golemis, E.A.5
-
10
-
-
33645220356
-
HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks
-
Pugacheva E.N., and Golemis E.A. HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks. Cell Cycle 5 (2006) 384-391
-
(2006)
Cell Cycle
, vol.5
, pp. 384-391
-
-
Pugacheva, E.N.1
Golemis, E.A.2
-
11
-
-
27144495462
-
The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome
-
Pugacheva E.N., and Golemis E.A. The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome. Nat. Cell Biol. 7 (2005) 937-946
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 937-946
-
-
Pugacheva, E.N.1
Golemis, E.A.2
-
12
-
-
0034959232
-
Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics
-
O'Neill G.M., and Golemis E.A. Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics. Mol. Cell Biol. 21 (2001) 5094-5108
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 5094-5108
-
-
O'Neill, G.M.1
Golemis, E.A.2
-
13
-
-
0033934340
-
The docking protein HEF1 is an apoptotic mediator at focal adhesion sites
-
Law S.F., O'Neill G.M., Fashena S.J., Einarson M.B., and Golemis E.A. The docking protein HEF1 is an apoptotic mediator at focal adhesion sites. Mol. Cell Biol. 20 (2000) 5184-5195
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 5184-5195
-
-
Law, S.F.1
O'Neill, G.M.2
Fashena, S.J.3
Einarson, M.B.4
Golemis, E.A.5
-
14
-
-
0032513128
-
T cell receptor-mediated tyrosine phosphorylation of Cas-L, a 105-kDa Crk-associated substrate-related protein, and its association of Crk and C3G
-
Ohashi Y., Tachibana K., Kamiguchi K., Fujita H., and Morimoto C. T cell receptor-mediated tyrosine phosphorylation of Cas-L, a 105-kDa Crk-associated substrate-related protein, and its association of Crk and C3G. J. Biol. Chem. 273 (1998) 6446-6451
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6446-6451
-
-
Ohashi, Y.1
Tachibana, K.2
Kamiguchi, K.3
Fujita, H.4
Morimoto, C.5
-
15
-
-
1542289021
-
Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor
-
Ren Y., Meng S., Mei L., Zhao Z.J., Jove R., and Wu J. Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor. J. Biol. Chem. 279 (2004) 8497-8505
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 8497-8505
-
-
Ren, Y.1
Meng, S.2
Mei, L.3
Zhao, Z.J.4
Jove, R.5
Wu, J.6
-
16
-
-
0039441744
-
Concerted activity of tyrosine phosphatase SHP-2 and focal adhesion kinase in regulation of cell motility
-
Manes S., Mira E., Gomez-Mouton C., Zhao Z.J., Lacalle R.A., and Martinez A.C. Concerted activity of tyrosine phosphatase SHP-2 and focal adhesion kinase in regulation of cell motility. Mol. Cell Biol. 19 (1999) 3125-3135
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 3125-3135
-
-
Manes, S.1
Mira, E.2
Gomez-Mouton, C.3
Zhao, Z.J.4
Lacalle, R.A.5
Martinez, A.C.6
-
17
-
-
34547610472
-
Inhibition of a specific N-glycosylation activity results in attenuation of breast carcinoma cell invasiveness-related phenotypes: inhibition of epidermal growth factor-induced dephosphorylation of focal adhesion kinase
-
Guo H.B., Randolph M., and Pierce M. Inhibition of a specific N-glycosylation activity results in attenuation of breast carcinoma cell invasiveness-related phenotypes: inhibition of epidermal growth factor-induced dephosphorylation of focal adhesion kinase. J. Biol. Chem. 282 (2007) 22150-22162
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 22150-22162
-
-
Guo, H.B.1
Randolph, M.2
Pierce, M.3
-
18
-
-
33744764925
-
A discoidin domain receptor 1/SHP-2 signaling complex inhibits alpha2beta1-integrin-mediated signal transducers and activators of transcription 1/3 activation and cell migration
-
Wang C.Z., Su H.W., Hsu Y.C., Shen M.R., and Tang M.J. A discoidin domain receptor 1/SHP-2 signaling complex inhibits alpha2beta1-integrin-mediated signal transducers and activators of transcription 1/3 activation and cell migration. Mol. Biol. Cell 17 (2006) 2839-2852
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 2839-2852
-
-
Wang, C.Z.1
Su, H.W.2
Hsu, Y.C.3
Shen, M.R.4
Tang, M.J.5
-
19
-
-
53049096122
-
Potential molecular mechanism for c-Src kinase-mediated regulation of intestinal cell migration
-
Mathew S., George S.P., Wang Y., Siddiqui M.R., Srinivasan K., Tan L., and Khurana S. Potential molecular mechanism for c-Src kinase-mediated regulation of intestinal cell migration. J. Biol. Chem. 283 (2008) 22709-22722
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 22709-22722
-
-
Mathew, S.1
George, S.P.2
Wang, Y.3
Siddiqui, M.R.4
Srinivasan, K.5
Tan, L.6
Khurana, S.7
-
20
-
-
33846995084
-
Crk-associated substrate lymphocyte type regulates transforming growth factor-beta signaling by inhibiting Smad6 and Smad7
-
Inamoto S., Iwata S., Inamoto T., Nomura S., Sasaki T., Urasaki Y., Hosono O., Kawasaki H., Tanaka H., Dang N.H., and Morimoto C. Crk-associated substrate lymphocyte type regulates transforming growth factor-beta signaling by inhibiting Smad6 and Smad7. Oncogene 26 (2007) 893-904
-
(2007)
Oncogene
, vol.26
, pp. 893-904
-
-
Inamoto, S.1
Iwata, S.2
Inamoto, T.3
Nomura, S.4
Sasaki, T.5
Urasaki, Y.6
Hosono, O.7
Kawasaki, H.8
Tanaka, H.9
Dang, N.H.10
Morimoto, C.11
-
21
-
-
0028136280
-
Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin
-
Milarski K.L., and Saltiel A.R. Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin. J. Biol. Chem. 269 (1994) 21239-21243
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 21239-21243
-
-
Milarski, K.L.1
Saltiel, A.R.2
-
22
-
-
0038190924
-
Development of an efficient "Substrate-trapping" mutant of Src homology phosphotyrosine phosphatase 2 and identification of the epidermal growth factor receptor, Gab1, and three other proteins as target substrates
-
Agazie Y.M., and Hayman M.J. Development of an efficient "Substrate-trapping" mutant of Src homology phosphotyrosine phosphatase 2 and identification of the epidermal growth factor receptor, Gab1, and three other proteins as target substrates. J. Biol. Chem. 278 (2003) 13952-13958
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 13952-13958
-
-
Agazie, Y.M.1
Hayman, M.J.2
-
23
-
-
3142751435
-
The major vault protein is a novel substrate for the tyrosine phosphatase SHP-2 and scaffold protein in epidermal growth factor signaling
-
Kolli S., Zito C.I., Mossink M.H., Wiemer E.A., and Bennett A.M. The major vault protein is a novel substrate for the tyrosine phosphatase SHP-2 and scaffold protein in epidermal growth factor signaling. J. Biol. Chem. 279 (2004) 29374-29385
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 29374-29385
-
-
Kolli, S.1
Zito, C.I.2
Mossink, M.H.3
Wiemer, E.A.4
Bennett, A.M.5
-
24
-
-
0029891787
-
Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae
-
Law S.F., Estojak J., Wang B., Mysliwiec T., Kruh G., and Golemis E.A. Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae. Mol. Cell Biol. 16 (1996) 3327-3337
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 3327-3337
-
-
Law, S.F.1
Estojak, J.2
Wang, B.3
Mysliwiec, T.4
Kruh, G.5
Golemis, E.A.6
-
25
-
-
3543036342
-
Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion
-
Yu D.H., Qu C.K., Henegariu O., Lu X., and Feng G.S. Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion. J. Biol. Chem. 273 (1998) 21125-21131
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21125-21131
-
-
Yu, D.H.1
Qu, C.K.2
Henegariu, O.3
Lu, X.4
Feng, G.S.5
-
26
-
-
0032932203
-
Regulation of early events in integrin signaling by protein tyrosine phosphatase SHP-2
-
Oh E.S., Gu H., Saxton T.M., Timms J.F., Hausdorff S., Frevert E.U., Kahn B.B., Pawson T., Neel B.G., and Thomas S.M. Regulation of early events in integrin signaling by protein tyrosine phosphatase SHP-2. Mol. Cell Biol. 19 (1999) 3205-3215
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 3205-3215
-
-
Oh, E.S.1
Gu, H.2
Saxton, T.M.3
Timms, J.F.4
Hausdorff, S.5
Frevert, E.U.6
Kahn, B.B.7
Pawson, T.8
Neel, B.G.9
Thomas, S.M.10
-
27
-
-
0029826289
-
Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST
-
Garton A.J., Flint A.J., and Tonks N.K. Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST. Mol. Cell Biol. 16 (1996) 6408-6418
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 6408-6418
-
-
Garton, A.J.1
Flint, A.J.2
Tonks, N.K.3
-
28
-
-
33646413397
-
Nitric oxide attenuates IGF-I-induced aortic smooth muscle cell motility by decreasing Rac1 activity: essential role of PTP-PEST and p130cas
-
Ceacareanu A.C., Ceacareanu B., Zhuang D., Chang Y., Ray R.M., Desai L., Chapman K.E., Waters C.M., and Hassid A. Nitric oxide attenuates IGF-I-induced aortic smooth muscle cell motility by decreasing Rac1 activity: essential role of PTP-PEST and p130cas. Am. J. Physiol. Cell Physiol. 290 (2006) C1263-C1270
-
(2006)
Am. J. Physiol. Cell Physiol.
, vol.290
-
-
Ceacareanu, A.C.1
Ceacareanu, B.2
Zhuang, D.3
Chang, Y.4
Ray, R.M.5
Desai, L.6
Chapman, K.E.7
Waters, C.M.8
Hassid, A.9
-
29
-
-
19044372472
-
Critical role for Gab2 in transformation by BCR/ABL
-
Sattler M., Mohi M.G., Pride Y.B., Quinnan L.R., Malouf N.A., Podar K., Gesbert F., Iwasaki H., Li S., Van Etten R.A., Gu H., Griffin J.D., and Neel B.G. Critical role for Gab2 in transformation by BCR/ABL. Cancer Cell 1 (2002) 479-492
-
(2002)
Cancer Cell
, vol.1
, pp. 479-492
-
-
Sattler, M.1
Mohi, M.G.2
Pride, Y.B.3
Quinnan, L.R.4
Malouf, N.A.5
Podar, K.6
Gesbert, F.7
Iwasaki, H.8
Li, S.9
Van Etten, R.A.10
Gu, H.11
Griffin, J.D.12
Neel, B.G.13
-
30
-
-
33645745233
-
Enhanced sensitivity to inhibition of SHP2, STAT5, and Gab2 expression in chronic myeloid leukemia (CML)
-
Scherr M., Chaturvedi A., Battmer K., Dallmann I., Schultheis B., Ganser A., and Eder M. Enhanced sensitivity to inhibition of SHP2, STAT5, and Gab2 expression in chronic myeloid leukemia (CML). Blood 107 (2006) 3279-3287
-
(2006)
Blood
, vol.107
, pp. 3279-3287
-
-
Scherr, M.1
Chaturvedi, A.2
Battmer, K.3
Dallmann, I.4
Schultheis, B.5
Ganser, A.6
Eder, M.7
-
31
-
-
33846223147
-
SHP-2 phosphatase is required for hematopoietic cell transformation by Bcr-Abl
-
Chen J., Yu W.M., Daino H., Broxmeyer H.E., Druker B.J., and Qu C.K. SHP-2 phosphatase is required for hematopoietic cell transformation by Bcr-Abl. Blood 109 (2007) 778-785
-
(2007)
Blood
, vol.109
, pp. 778-785
-
-
Chen, J.1
Yu, W.M.2
Daino, H.3
Broxmeyer, H.E.4
Druker, B.J.5
Qu, C.K.6
-
32
-
-
30044434225
-
A role for the scaffolding adapter GAB2 in breast cancer
-
Bentires-Alj M., Gil S.G., Chan R., Wang Z.C., Wang Y., Imanaka N., Harris L.N., Richardson A., Neel B.G., and Gu H. A role for the scaffolding adapter GAB2 in breast cancer. Nat. Med. 12 (2006) 114-121
-
(2006)
Nat. Med.
, vol.12
, pp. 114-121
-
-
Bentires-Alj, M.1
Gil, S.G.2
Chan, R.3
Wang, Z.C.4
Wang, Y.5
Imanaka, N.6
Harris, L.N.7
Richardson, A.8
Neel, B.G.9
Gu, H.10
|