Visualization of inhibitory Ly49 receptor specificity with soluble major histocompatibility complex class I tetramers

European Journal of Immunology

Volumn 30, Issue 1, 2000, Pages 300-307

  Michaëlsson, Jakob ^a,d   Achour, Adnane ^a   Salcedo, Margarita ^b,e   Kåse Sjöström, Anna ^a   Sundbäck, Jonas ^a   Harris, Robert A ^c   Kärre, Klas ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b INSERM   (France)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d KAROLINSKA INSTITUTE   (Sweden)

^e IDM   (France)

Author keywords

Glycosylation; MHC class I; NK cell; Peptide

Indexed keywords

GLYCAN; LYMPHOCYTE RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TETRAMER;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING;

ANIMALS; ANTIGENS, LY; CELL LINE; H-2 ANTIGENS; HISTOCOMPATIBILITY ANTIGENS CLASS I; LECTINS, C-TYPE; MICE; MICE, INBRED BALB C; RATS; RECEPTORS, IMMUNOLOGIC;

EID: 0343340433     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200001)30:1<300::AID-IMMU300>3.0.CO;2-S     Document Type: Article

References (42)

1. Yokoyama, W. M., Natural Killer Cells. In Paul, W. E. (Ed.), 'Fundamental Immunology', 4th Edn., Lippincot-Raven Publishers, Philadelphia 1999, p. 575-603.
2. Kärre, K., Ljunggren, H. G., Piontek, G. and Kiessling, R., Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. Nature 1986. 319: 675-678.
3. Ljunggren, H. G. and Kärre, K., In search of the 'missing self': MHC molecules and NK cell recognition. Immunol. Today 1990. 11: 237-244.
4. Wagtmann, N., Biassoni, R., Cantoni, C., Verdiani, S., Malnati, M. S., Vitale, M., Bottino, C., Moretta, L., Moretta, A. and Long, E. O., Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. Immunity 1995. 2: 439-449.
5. Colonna, M. and Samaridis, J., Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. Science 1995. 268: 405-408.
6. Rojo, S., Burshtyn, D. N., Long, E. O. and Wagtmann, N., Type I transmembrane receptor with inhibitory function in mouse mast cells and NK cells. J. Immunol. 1997. 158: 9-12.
7. Karlhofer, F. M., Ribaudo, R. K. and Yokoyama, W. M., MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells. Nature 1992. 358: 66-70.
8. Lazetic, S., Chang, C., Houchins, J. P., Lanier, L. L. and Phillips, J. H., Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits. J. Immunol. 1996. 157: 4741-4745.
9. Carretero, M., Cantoni, C., Bellon, T., Bottino, C., Biassoni, R., Rodriguez, A., Perez-Villar, J. J., Moretta, L., Moretta, A. and Lopez-Botet, M., The CD94 and NKG2-A C-type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules. Eur. J. Immunol. 1997. 27: 563-567.
10. Vance, R. E., Kraft, J. R., Altman, J. D., Jensen, P. E. and Raulet, D. H., Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b). J. Exp. Med. 1998. 188: 1841-1848.
11. Weis, W. I., Taylor, M. E. and Drickamer, K., The C-type lectin superfamily in the immune system. Immunol. Rev. 1998. 163: 19-34.
12. Takei, F., Brennan, J. and Mager, D. L., The Ly-49 family: genes, proteins and recognition of class I MHC. Immunol. Rev. 1997. 155: 67-77.
13. McQueen, K. L., Freeman, J. D., Takei, F. and Mager, D. L., Localization of five new Ly49 genes, including three closely related to Ly49c. Immunogenetics 1998. 48: 174-183.
14. Moretta, A., Sivori, S., Vitale, M., Pende, D., Morelli, A., Augugliaro, R., Bottino, C. and Moretta, L., Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells. J. Exp. Med. 1995. 182: 875-884.
15. Kane, K. P., Ly-49 mediates EL4 lymphoma adhesion to isolated class I major histocompatibility complex molecules. J. Exp. Med. 1994. 179: 1011-1015.
16. p inhibits murine NK cells via the inhibitory receptor Ly49A. J. Immunol. 1999. 162: 7010-7014.
17. Mason, L. H., Ortaldo, J. R., Young, H. A., Kumar, V., Bennett, M. and Anderson, S. K., Cloning and functional characteristics of murine large granular lymphocyte-1: a member of the Ly-49 gene family (Ly-49G2). J. Exp. Med. 1995. 182: 293-303.
18. d on protection against NK cells expressing the inhibitory receptor Ly49G2. Eur. J. Immunol. 1998. 28: 4198-4206.
19. Raulet, D. H., Held, W., Correa, I., Dorfman, J. R., Wu, M. F. and Corral, L., Specificity, tolerance and developmental regulation of natural killer cells defined by expression of class I-specific Ly49 receptors. Immunol. Rev. 1997. 155: 41-52.
20. Lian, R. H., Li, Y., Kubota, S., Mager, D. L. and Takei, F., Recognition of class I MHC by NK receptor Ly-49C: identification of critical resudues. J. Immunol. 1999. 162: 7271-7276.
21. Allan, D. S., Colonna, M., Lanier, L. L., Churakova, T. D., Abrams, J. S., Ellis, S. A., McMichael, A. J. and Braud, V. M., Tetrameric complexes of human histocompatibility leukocyte antigen (HLA)-G bind to peripheral blood myelomonocytic cells. J. Exp. Med. 1999. 189: 1149-1156.
22. Braud, V. M., Allan, D. S., O'Callaghan, C. A., Söderström, K., D'Andrea, A., Ogg, G. S., Lazetic, S., Young, N. T., Bell, J. I., Phillips, J. H., Lanier, L. L. and McMichael, A. J., HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 1998. 391:795-799.
23. Salcedo, M., Bousso, P., Ljunggren, H. G., Kourilsky, P. and Abastado, J. P., The Qa-1b molecule binds to a large subpopulation of murine NK cells. Eur. J. Immunol. 1998. 28: 4356-4361.
24. Lian, R. H., Freeman, J. D., Mager, D. L. and Takei, F., Role of conserved glycosylation site unique to murine class I MHC in recognition by Ly-49 NK cell receptor. J. Immunol. 1998. 161: 2301-2306.
25. Matsumoto, N., Ribaudo, R. K., Abastado, J. P., Margulies, D. H. and Yokoyama, W. M., The lectin-like NK cell receptor Ly-49A recognizes a carbohydrate-independent epitope on its MHC class I ligand. Immunity 1998. 8: 245-254.
26. Franksson, L., E. M., Sundbäck, J., Achour, A., Bernlind, J. and Kärre, K., Peptide-dependency and -selectivity of the natural killer cell inhibitory receptor Ly-49C. Eur. J. Immunol. 1999. 29: 2748-2758.
27. Hanke, T., Takizawa, M., McMahon, C. W., Busch, D. H., Pamer, E. G., Miller, J. D., Altman, J. D., Liu, Y., Cado, D., Lemonnier, F. A., Bjorkman, P. J. and Raulet, D. H., Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors. Immunity 1999. 11: 67-77.
28. Held, W., Dorfman, J. R., Wu, M. F. and Raulet, D. H., Major histocompatibility complex class I-dependent skewing of the natural killer cell Ly49 receptor. Eur. J. Immunol. 1996. 26: 2286-2292.
29. Olsson, M. Y., Kärre, K. and Sentman, C. L., Altered phenotype and function of natural killer cells expressing the major histocompatibility complex receptor Ly-49 in mice transgenic for its ligand. Proc. Natl. Acad. Sci. USA 1995, 92: 1649-1653.
30. Daniels, B. F., Karlhofer, F. M., Seaman, W. E. and Yokoyama, W. M., A natural killer cell receptor specific for a major histocompatibility complex class I molecule. J. Exp. Med. 1994. 180: 687-692.
31. Correa, I. and Raulet, D. H., Binding of diverse peptides to MHC class I molecules inhibits target cell lysis by activated natural killer cells. Immunity 1995. 2: 61-71.
32. Orihuela, M., Margulies, D. H. and Yokoyama, W. M., The natural killer cell receptor Ly-49A recognizes a peptide-induced conformational determinant on its major histocompatibility complex class I ligand. Proc. Natl. Acad. Sci. USA 1996. 93: 11792-11797.
33. Malnati, M. S., Peruzzi, M., Parker, K. C., Biddison, W. E., Ciccone, E., Ciccone, E., Moretta, A. and Long, E. O., Peptide specificity in the recognition of MHC class I by natural killer cell clones. Science 1995. 267: 1016-1018.
34. Peruzzi, M., Parker, K. C., Long, E. O. and Malnati, M. S., Peptide sequence requirements for the recognition of HLA-B*2705 by specific natural killer cells. J. Immunol. 1996. 157: 3350-3356.
35. Peruzzi, M., Wagtmann, N. and Long, E. O., A p70 killer cell inhibitory receptor specific for several HLA-B allotypes discriminates among peptides bound to HLA-B*2705. J. Exp. Med. 1996. 184: 1585-1590.
36. Rajagopalan, S. and Long, E. O., The direct binding of a p58 killer cell inhibitory receptor to human histocompatibility leukocyte antigen (HLA)-Cw4 exhibits peptide selectivity. J. Exp. Med. 1997. 185: 1523-1528.
37. Chang, C. S., Shen, L., Gong, D. E. and Kane, K. P., Major histocompatibility complex class I-dependent cell binding to isolated Ly-49A: evidence for high-avidity interaction. Eur. J. Immunol. 1996. 26: 3219-3223.
38. Nakamura, M. C., Niemi, E. C., Fisher, M. J., Shultz, L. D., Seaman, W. E. and Ryan, J. C., Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase. J. Exp. Med. 1997. 185: 673-684.
39. Bousso, P., Casrouge, A., Altman, J. D., Haury, M., Kannellopoulos, J., Abastado, J. P. and Kourilsky, P., Individual variations in the murine T cell response to a specific peptide reflect variability in naive repertoires. Immunity 1998. 9: 169-178.
40. Garboczi, D. N., Hung, D. T. and Wiley, D. C., HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides. Proc. Natl. Acad. Sci. USA 1992. 89: 3429-3433.
41. d: expression, refolding and crystallization. Acta Crystallogr. D 1999. 55: 260-262.
42. Altman, J. D., Moss, P. A. H., Goulder, P. J. R., Barouch, D. H., McHeyzer-Williams, M. G., Bell, J. I., McMichael, A. J. and Davis, M. M., Phenotypic analysis of antigen-specific T lymphocytes. Science 1996. 274: 94-96.