-
1
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, Willingham MC. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci USA 1987;84:7735-7738.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
2
-
-
0042132423
-
Expression of a multidrug-resistance gene in human tumors and tissues
-
Fojo AT, Ueda K, Slamon DJ, Poplack DG, Gottesman MM, Pastan I. Expression of a multidrug-resistance gene in human tumors and tissues. Proc Natl Acad Sci USA 1987;84:265-269.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 265-269
-
-
Fojo, A.T.1
Ueda, K.2
Slamon, D.J.3
Poplack, D.G.4
Gottesman, M.M.5
Pastan, I.6
-
3
-
-
0037457802
-
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: An overview
-
Schinkel AH, Jonker JW. Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: An overview. Adv Drug Deliv Rev. 2003;55:3-29.
-
(2003)
Adv Drug Deliv Rev
, vol.55
, pp. 3-29
-
-
Schinkel, A.H.1
Jonker, J.W.2
-
4
-
-
0000712439
-
Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites
-
Cordon-Cardo C, O'Brien JP, Casals D, et al. Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites. Proc Natl Acad Sci USA 1989;86:695-698.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 695-698
-
-
Cordon-Cardo, C.1
O'Brien, J.P.2
Casals, D.3
-
5
-
-
0032900953
-
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
-
Ambudkar SV, Dey S, Hrycyna CA, Ramachandra M, Pastan I, Gottesman MM. Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annu Rev Pharmacol Toxicol 1999;39:361-368.
-
(1999)
Annu Rev Pharmacol Toxicol
, vol.39
, pp. 361-368
-
-
Ambudkar, S.V.1
Dey, S.2
Hrycyna, C.A.3
Ramachandra, M.4
Pastan, I.5
Gottesman, M.M.6
-
6
-
-
0033980182
-
-
Fromm MF. P-glycoprotein. A defense mechanism limiting oral bioavailability and CNS accumulation of drugs. Int J Clin Pharmacol Ther 2000;38:69-74.
-
Fromm MF. P-glycoprotein. A defense mechanism limiting oral bioavailability and CNS accumulation of drugs. Int J Clin Pharmacol Ther 2000;38:69-74.
-
-
-
-
7
-
-
1642523162
-
Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance
-
Marzolini C, Paus E, Buclin T, Kim RB. Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance. Clin Pharmacol Ther 2004;75:13-33.
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 13-33
-
-
Marzolini, C.1
Paus, E.2
Buclin, T.3
Kim, R.B.4
-
9
-
-
10744222684
-
Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene
-
Kroetz DL, Pauli-Magnus C, Hodges LM, et al. Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene. Pharmacogenetics 2003;13:481-494.
-
(2003)
Pharmacogenetics
, vol.13
, pp. 481-494
-
-
Kroetz, D.L.1
Pauli-Magnus, C.2
Hodges, L.M.3
-
10
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer S, Burk O, von Richter O, et al. Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci USA 2000;97:3473-3478.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
von Richter, O.3
-
11
-
-
3042772026
-
Identification of functionally variant MDR1 alleles among European Americans and African Americans
-
Kim RB, Leake BF, Choo EF, et al. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin Pharmacol Ther 2001;70:189-199.
-
(2001)
Clin Pharmacol Ther
, vol.70
, pp. 189-199
-
-
Kim, R.B.1
Leake, B.F.2
Choo, E.F.3
-
12
-
-
0013095102
-
MDR1 genotype-related pharmacokinetics and pharmacodynamics
-
Sakaeda T, Nakamura T, Okumura K. MDR1 genotype-related pharmacokinetics and pharmacodynamics. Biol Pharm Bull 2002;25:1391-1400.
-
(2002)
Biol Pharm Bull
, vol.25
, pp. 1391-1400
-
-
Sakaeda, T.1
Nakamura, T.2
Okumura, K.3
-
13
-
-
23244437043
-
MDR1 genetic polymorphisms and comparison of MDR1 haplotype profiles in Korean and Vietnamese populations
-
Lee SS, Kim SY, Kim WY, et al. MDR1 genetic polymorphisms and comparison of MDR1 haplotype profiles in Korean and Vietnamese populations. Ther Drug Monit 2005;27:531-535.
-
(2005)
Ther Drug Monit
, vol.27
, pp. 531-535
-
-
Lee, S.S.1
Kim, S.Y.2
Kim, W.Y.3
-
14
-
-
4644341131
-
Genotyping of the triallelic variant G2677T/A in MDR1 using LightCycler with locked- nucleic- acid- modified hybridization probes
-
Arjomand-Nahad F, Diefenbach K, Landt O, Gaikovitch E, Roots I. Genotyping of the triallelic variant G2677T/A in MDR1 using LightCycler with locked- nucleic- acid- modified hybridization probes. Anal Biochem 2004;334:201-203.
-
(2004)
Anal Biochem
, vol.334
, pp. 201-203
-
-
Arjomand-Nahad, F.1
Diefenbach, K.2
Landt, O.3
Gaikovitch, E.4
Roots, I.5
-
15
-
-
25644451317
-
Simultaneous determination of single nucleotide polymorphisms of MDR1 genes by electrochemical DNA chip
-
Nakamura T, Sakaeda T, Takahashi M, et al. Simultaneous determination of single nucleotide polymorphisms of MDR1 genes by electrochemical DNA chip. Drug Metab Pharmkinet 2005;20:219-225.
-
(2005)
Drug Metab Pharmkinet
, vol.20
, pp. 219-225
-
-
Nakamura, T.1
Sakaeda, T.2
Takahashi, M.3
-
16
-
-
0024605518
-
Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS)
-
Newton CR, Graham A, Heptinstall LE, et al. Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS). Nucleic Acids Res 1989;17:2503-2516.
-
(1989)
Nucleic Acids Res
, vol.17
, pp. 2503-2516
-
-
Newton, C.R.1
Graham, A.2
Heptinstall, L.E.3
-
17
-
-
0026566560
-
Allele specific amplification by tetra-primer PCR
-
Ye S, Humphries S, Green F. Allele specific amplification by tetra-primer PCR. Nucleic Acids Res 1992;20:1152.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 1152
-
-
Ye, S.1
Humphries, S.2
Green, F.3
-
18
-
-
33645460845
-
Multiplex tetra-primer amplification refractory mutation system PCR to detect 6 common germline mutations of the MUTYH gene associated with polyposis and colorectal cancer
-
Piccioli P, Serra M, Gismondi V, et al. Multiplex tetra-primer amplification refractory mutation system PCR to detect 6 common germline mutations of the MUTYH gene associated with polyposis and colorectal cancer. Clin Chem 2006;52:739-743.
-
(2006)
Clin Chem
, vol.52
, pp. 739-743
-
-
Piccioli, P.1
Serra, M.2
Gismondi, V.3
-
19
-
-
0036667956
-
Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations
-
Tang K, Ngoi S, Gwee P, et al. Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations. Pharmacogenetics 2002;12:437-450.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 437-450
-
-
Tang, K.1
Ngoi, S.2
Gwee, P.3
-
20
-
-
0034997034
-
Expression of P-glycoprotein in human placenta: Relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene
-
Tanabe M, Ieiri I, Nagata N, et al. Expression of P-glycoprotein in human placenta: Relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene. J Pharmacol Exp Ther 2001;297:1137-1143.
-
(2001)
J Pharmacol Exp Ther
, vol.297
, pp. 1137-1143
-
-
Tanabe, M.1
Ieiri, I.2
Nagata, N.3
-
21
-
-
0035104031
-
Frequency of single nucleotide polymorphisms in the nucleotide in the P-glycoprotein drug transporter MDR1 gene in white subjects
-
Cascorbi I, Gerloff T, Johne A, et al. Frequency of single nucleotide polymorphisms in the nucleotide in the P-glycoprotein drug transporter MDR1 gene in white subjects. Clin Pharmacol Ther 2001;69:169-174.
-
(2001)
Clin Pharmacol Ther
, vol.69
, pp. 169-174
-
-
Cascorbi, I.1
Gerloff, T.2
Johne, A.3
-
22
-
-
0036881077
-
The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol
-
Siegmund W, Ludwig K, Giessmann T, et al. The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol. Clin Pharmacol Ther 2002;72:572-583.
-
(2002)
Clin Pharmacol Ther
, vol.72
, pp. 572-583
-
-
Siegmund, W.1
Ludwig, K.2
Giessmann, T.3
-
23
-
-
0029589537
-
Meta-analysis: A method for synthesizing research
-
D'Agostino RB, Weintraub M. Meta-analysis: A method for synthesizing research. Clin Pharmacol Ther 1995;58:605-616.
-
(1995)
Clin Pharmacol Ther
, vol.58
, pp. 605-616
-
-
D'Agostino, R.B.1
Weintraub, M.2
|