Platelet GP IIIA polymorphism HPA-1 (PLA1/2) is associated with hypertension as the primary cause for end-stage renal disease in hemodialysis patients from Greece

In Vivo

Volumn 23, Issue 1, 2009, Pages 177-182

  Chiras, Theodore ^a   Papadakis, Emmanuel D ^a   Katopodi, Aggeliki ^a   Chatzianesti, Efrosini ^a   Fourtounas, Kostas ^a   Papakonstantinou, Stamatina ^a   Theodoropoulos, Ilias ^a   Dakouras, Anastasios ^a   Zerefos, Nikolas ^a   Valis, Dimitrios ^a   Tzanatos Exarchou, Helen ^a  

^a Ygeia Hospital   (Greece)

Author keywords

Haemodialysis; Human platelet antigens; Hypertension; Platelet glycoproteins; Platelets

Indexed keywords

GLYCOPROTEIN IIIA; HUMAN PLATELET ANTIGEN 1; HUMAN PLATELET ANTIGEN 2; HUMAN PLATELET ANTIGEN 3; HUMAN PLATELET ANTIGEN 5; THROMBOCYTE ANTIGEN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENOTYPE; GREECE; HEMODIALYSIS PATIENT; HUMAN; HYPERTENSION; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, HUMAN PLATELET; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; HYPERTENSION; INTEGRIN BETA3; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RENAL DIALYSIS; YOUNG ADULT;

EID: 63049128124     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Metcalfe P, Watkins NA, Ouwehand WH, Kaplan C, Newman P, Kekomaki R, M de Haas, Aster R, Shibata Y, Smith J, Kiefel V and Santoso S: Nomenclature of human platelet antigens. Vox Sanguinis 85: 240-245, 2003.
2. Beer JH, Pederiva S and Pontiggia L: Genetics of platelet receptor singlenucleotide polymorphisms: clinical implications in thrombosis. Ann Med 32: 10-14, 2000.
3. a2, are associated with a leucine33/ proline33 amino acid polymorphism in membrane glycoprotein IIIa and are distinguishable by DNA typing. J Clin Invest 83: 1778-1781, 1989.
4. b alloantigen system. Blood 75: 2343-2348, 1990.
5. Kuijpers RWAM, Faber NM, Cuypers HTM, Ouwehand WH and von dem Borne AEGK: The N-terminal globular domain of the human platelet glycoprotein Iba has a methionine 145/threonine 145 amino acid polymorphism which is associated with the HPA-2 (Ko) alloantigens. J Clin Invest 89: 381-384, 1992.
6. Mazzucato M, Pradella P, de Angelis V, Steffan A and de Marco L: Frequency and functional relevance of genetic threonine145/methionine 145 dimorphism in platelet glycoprotein Iba in an Italian population. Transfusion 36: 891-894,1996.
7. b, are associated with a single amino acid polymorphism on glycoprotein Ia (integrin a2). J Clin Invest 92: 2427-2432, 1993.
8. Antoniades C, Tousoulis D, Vasiliadou C, Stefanadi E, Marinou K and Stefanadis C: genetic polymorphisms of platelet glycoprotein Ia and the risk for premature myocardial infarction: effects on the release of sCD40L During the Acute Phase of Premature Myocardial Infarction. J Am Coll Cardiol 47: 1959-1966, 2006.
9. Kluter H, Fehlau K, Panzer S, Kirchner H and Bein G: Rapid typing for human platelet antigen systems- 1, -2, -3 and -5 by PCR amplification with sequence-specific primers. Vox Sanguinis 71(2): 121-125, 1996.
10. Prozialeck WC and Edwards JR: Cell adhesion molecules in chemically-induced renal injury. Pharmacol Ther 114(1): 74-93, 2007.
11. Holden RM, Harman GJ, Wang M, Holland D and Day AG: Major bleeding in hemodialysis patients. Clin J Am Soc Nephrol 3(1): 105-10, 2008.
12. Ho SJ, Gemmell R and Brighton TA: Platelet function testing in uremic patients. Hematology 13(1): 49-58, 2008
13. Salobir B, Sabovic M, Zupn IP and Ponikvar JB: Platelet (dys)function and plasma plasminogen levels in hemodialysis patients. Ther Apher Dial 12(2): 133-6, 2008.
14. Metcalfe P and Waters AH: HPA-1 typing by PCR amplification with sequence-specific primers (PCR-SSP): a rapid and simple technique. Br J Haematol 85(1): 227-229, 1993.
15. Mann JFE: What's new in hypertension? Nephrol Dial Transplant 22: 47-52, 2007.
16. Bernardo RI and Nosratola DV: Salt-sensitive hypertension- update of novel findings. Neprol Dial Transplant 22: 992-995, 2007
17. Sabbagh AS, Taher AT, Zaatari GS and Mahfouz RA: Gene frequencies of the HPA-1 platelet antigen alleles in the Lebanese population. Transfus Med 17(6): 473-8, 2007.
18. Theodoropoulos I, Christopoulos C, Metcalfe P, Dimitriadou E, Economopoulos P and Loukopoulos D: The effect of human platelet alloantigen polymorphisms on the in vitro responsiveness to adrenaline and collagen. Br J Haemtol 114: 387-393, 2001.
19. Wagner KR, Giles WH, Johnson CJ, Ou CY, Bray PF, Goldschmidt-Clermont PJ, Croft JB, Brown VK, Stern BJ, Feeser BR, Buchholz DW, Earley CJ, Macko RF, McCarter RJ, Sloan MA, Stolley PD, Wityk RJ, Wozniak MA, Price TR and Kittner SJ: Platelet glycoprotein receptor IIIa polymorphism P1A2 and ischemic stroke risk: the Stroke Prevention in Young Women Study. Stroke 29: 581-585, 1998.
20. Boudoulas KD, Cooke GE, Roos CM, Bray PF and Goldschmidt-Clermont PJ: The P1A polymorphism of glycoprotein IIIa functions as a modifier for the effect of estrogen on platelet aggregation. Arch Pathol Lab Med 125: 112-115, 2001.
21. Clemetson KJ and Clemetson JM: Integrins and cardiovascular disease. Cell Mol Life Sci 54: 502-513, 1998.
22. Stouffer GA, Hu Z, Sajid M, Li H, Jin G, Nakada MT, Hanson SR and Runge MS: Beta-3 Integrins are up-regulated after vascular injury and modulate thrombospondin- and thrombin-induced proliferation of cultured smooth muscle cells. Circulation 97: 907-915, 1998.
23. Kimoto E, Shoji T, Shinohara K, Hatsuda S, Mori K, Fukumoto S, Koyoama H, Emoto M, Okuno Y and Nishizawa Y: regional arterial stiffness in patients with type 2 diabetes and chronic kidney disease. J Am Soc Nephrol 17: 2245-2252, 2006
24. Loncar R, Stoldt V, Hellmig S, Zotz RB, Mihalj M and Scharf RE: HPA-I polymorphism of αIIbβ3 modulates platelet adhesion onto immobilized fibrinogen in an in vitro flow system. Thrombosis J 5: 2, 2007
25. Weiss EJ, Bray PF, Tayback M, Schulman SP, Kickler TS, Becker LC, Weiss JL, Gerstenblith G and Goldschmidt-Clermont PJ: A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis. N Engl J Med 334: 1090-1094, 1996.
26. Ting HH, Yang EH and Rihal CS: Narrative Review: reperfusion strategies for ST-segment elevation myocardial infarction. Ann Intern Med 145: 610-617, 2006.
27. Carter AM, Ossei-Gerning N, Wilson IJ and Grant PJ: Association of the platelet Pl(A) polymorphism of glycoprotein IIb/IIIa and the fibrinogen Bbeta 448 polymorphism with myocardial infarction and extent of coronary artery disease. Circulation 96: 1424-1431, 1997.
28. Garg UC, Arnett DK, Folsom AR, Province MA, Williams RR and Eckfeldt JH: Lack of association between platelet glycoprotein IIb/IIIa receptor PlA polymorphism and coronary artery disease or carotid intima-media thickness. Thromb Res 89: 85-89, 1998.
29. Zhu MM, Weedon J and Clark LT: Meta-analysis of the association of platelet glycoprotein IIIa PlA1/A2 polymorphism with myocardial infarction. Am J Cardiol 86: 1000-1005, 2000.
30. Aleksic N, Juneja H, Folsom AR, Ahn C, Boerwinkle E, Chambless LE and Wu KK: Platelet PlA2 allele and incidence of coronary heart disease: results from the Atherosclerosis Risk In Communities (ARIC) Study. Circulation 102: 1901-1905, 2000.
31. Di Castelnuovo A, De Gaetano G, Donati MB and Iacoviello L: Platelet glycoprotein receptor IIIa polymorphism PLA1/PLA2 and coronary risk: a meta-analysis. Thromb Haemost 85: 626-633, 2001.
32. Zotz RB, Winkelmann BR, Müller C, Boehm BO, März W and Scharf RE: Association of polymorphisms of platelet membrane integrins alpha IIb(beta)3 (HPA-1b/Pl) and alpha2(beta)1 (alpha807TT) with premature myocardial infarction. J Thromb Haemost 3(7): 1522-1529, 2005.
33. Mikkelsson J, Perola M, Laippala P, Savolainen V, Pajarinen J, Lalu K, Penttila A and Karhunen PJ: Glycoprotein IIIa Pl(A) polymorphism associates with progression of coronary artery disease and with myocardial infarction in an autopsy series of middle-aged men who died suddenly. Arch Pathol Lab Med 19: 2573-2578, 1999.
34. Goldschmidt-Clermont PJ, Coleman LD, Pham YM, Cooke GE, Shear WS, Weiss EJ et al: Higher prevalence of GPIIIa PlA2 polymorphism in siblings of patients with premature coronary heart disease. Arch Pathol Lab Med 123: 1223-1229, 1999.
35. Carlsson LE, Greinacher A, Spitzer C, Walther R and Kessler C: Polymorphisms of the human platelet antigens HPA-1, HPA-2, HPA-3, and HPA-5 on the platelet receptors for fibrinogen (GPIIb/IIIa), von Willebrand factor (GPIb/IX), and collagen (GPIa/IIa) are not correlated with an increased risk for stroke. Stroke 28(7): 1392-5, 1997.
36. Carter AM, Catto AJ, Bamford JM and Grant PJ: Association of the platelet glycoprotein IIb HPA-3 polymorphism with survival after acute ischemic stroke. Stroke 30(12): 2606-11, 1999.
37. Meiklejohn DJ, Vickers MA, Morrison ER, Dijkhuisen R, Moore I, Urbaniak SJ and Greaves M: In vivo platelet activation in atherothrombotic stroke is not determined by polymorphisms of human platelet glycoprotein IIIa or Ib. Br J Haematol 112(3): 621-31, 2001.
38. Saidi S, Mahjoub T, Slamia LB, Ammou SB, Al-Subaie AM and Almawi WY: Polymorphisms of the human platelet alloantigens HPA-1, HPA-2, HPA-3, and HPA-4 in ischemic stroke. Am J Hematol 83(7): 570-573, 2008.
39. Feng D, Lindpaintner K, Larson MG, Rao VS, O'Donnell CJ, Lipinska I, Schmitz C, Sutherland PA, Silbershatz H, D'Agostino RB, Muller JE, Myers RH, Levy D and Tofler GH: Increased platelet aggregability associated with platelet GPIIIa PlA2 polymorphism: the Framingham Offspring Study. Arterioscler Thromb Vasc Biol 19: 1142-1147, 1999.
40. Goodall AH, Curzen N, Panesar M, Hurd C, Knight CJ, Ouwehand WH and Fox KM: Increased binding of fibrinogen to glycoprotein IIIa-proline33 (HPA-1b, PlA2, Zwb) positive platelets in patients with cardiovascular disease. Eur Heart J 20: 742-747, 1999.
41. Michelson AD, Furman MI, Goldschmidt-Clermont P, Mascelli MA, Hendrix C, Coleman L, Hamlington J, Barnard MR, Kickler T, Christie DJ, Kundu S and Bray PF: Platelet GP IIIa Pl(A) polymorphisms display different sensitivities to agonists. Circulation 101: 1013-1018, 2000.
42. Iniesta JA, González-Conejero R, Piqueras C, Vicente V and Corral J: Platelet GP IIIa polymorphism HPA-1 (PlA) protects against subarachnoid hemorrhage. Stroke 35: 2282-2286, 2004.