Polymorphisms of the human platelet antigens HPA-1, HPA-2, HPA-3, and HPA-5 on the platelet receptors for fibrinogen (GPBIIb/IIIa), von Willebrand factor (GPIb/IX), and collagen (GPIa/IIa) are not correlated with an increased risk for stroke

Stroke

Volumn 28, Issue 7, 1997, Pages 1392-1395

  Carlsson, Lena E ^a   Greinacher, Andreas ^a   Spitzer, Carsten ^a   Walther, Reinhard ^a   Kessler, Christof ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Antigens, human platelet; Collagen; Fibrinogen; Platelets; Polymorphism (genetics); Von Willebrand factor

Indexed keywords

COLLAGEN; THROMBOCYTE ANTIGEN; THROMBOCYTE RECEPTOR; VON WILLEBRAND FACTOR;

ADULT; AGED; ARTICLE; CEREBROVASCULAR DISEASE; DNA DETERMINATION; DNA POLYMORPHISM; FEMALE; GENETIC RISK; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK ASSESSMENT; STROKE;

EID: 0030793970     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.28.7.1392     Document Type: Article

References (26)

1. Newman PJ, Valentin N. Human platelet alloantigens: recent findings, new perspectives. Thromb Haemost. 1995;74:234-239.
2. Weiss EJ, Bray PF, Tayback M, Schulman SP, Kickler TS, Becker LC, Weiss JL, Gerstenblith G, Goldschmidt-Clermont PJ. A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis. N Engl J Med. 1996;334:1090-1094.
3. a polymorphism and myocardial infarction. N Engl J Med. 1996;335: 1071-1072. Letter.
4. a polymorphism and myocardial infarction. N Engl J Med. 1996; 335:1072-1073. Letter.
5. A1/A2 polymorphism of platelet glycoprotein IIIa and risks of myocardial infarction, stroke and venous thrombosis. Lancet. 1997;349:385-388.
6. Nurden AT. Polymorphisms of platelet receptors as risk factors in coronary thrombosis. Eur Heart J. 1996;17:1293-1294.
7. Newman PJ. Platelet alloantigens: cardiovascular as well as immunological risk factors? Lancet. 1997;349:370-371. Commentary.
8. a2, are associated with a Leucine33/Proline33 amino acid polymorphism in membrane glycoprotein IIIa and are distinguishable by DNA typing. J Clin Invest. 1989;83:1778-1781.
9. b alloantigen system. Blood. 1990;75:2343-2348.
10. Kuijpers RWAM, Faber NM, Cuypers HTM, Ouwehand WH, von dem Borne AEGK. The N-terminal globular domain of the human platelet glycoprotein Iba has a methionine 145/threonine 145 amino acid polymorphism which is associated with the HPA-2 (Ko) alloantigens. J Clin Invest. 1992;89:381-384.
11. Mazzucato M, Pradella P, de Angelis V, Steffan A, de Marco L. Frequency and functional relevance of genetic threonin145/ methionin145 dimorphism in platelet glycoprotein Iba in an Italian population. Transfusion. 1996;36:891-894.
12. b, are associated with a single amino acid polymorphism on glycoprotein Ia (integrin α2). J Clin Invest. 1993;92:2427-2432.
13. Kiefel V, Santoso S, Weisheit M, Mueller-Eckhardt C. Monoclonal antibody-specific immobilization of platelet antigens (MAIPA): a new tool for the identification of platelet-reactive antibodies. Blood. 1987;70:1722-1726.
14. A2 genotypes. Br J Haematol. 1992;81:113-117.
15. A2. Tissue Antigens. 1995;46: 374-381.
16. a1, HPA-1a) form of platelet glycoprotein IIIa from a V gene phage display library. Blood. 1995;86: 4430-4436.
17. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988;16:1215.
18. Klüter H, Fehlau K, Panzer S, Kirchner H, Bein G. Rapid typing for human platelet antigen systems -1, -2, -3 and -5 by PCR amplification with sequence specific primers. Vox Sang. 1996;71:121-125.
19. Bein G, Hackstein H, Klüter H. DNA typing of human antigen systems -1, -2, -3 and -5 in B-lymphoblastoid cell lines of the International Histocompatibility Workshop. Tissue Antigens. 1997; 49:443-447.
20. Harker LA. Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis. Circulation. 1986;73:206-223.
21. Antiplatelet Trialists' Collaboration. Collaborative overview of randomised trials of antiplatelet therapy, I: prevention of death, myocardial infarction and stroke by prolonged antiplatelet therapy in various categories of patients. BMJ. 1994;308:81-104.
22. Bornstein NM, Karepov VG, Aronovich BD, Gorbulev AY, Treves TA, Korczyn AD. Failure of aspirin treatment after stroke. Stroke. 1994;25:275-277.
23. A), Ko, Bak and Br (HPA-1, 2, 3, 5). Br J Haematol. 1995;89: 169-176.
24. Legler TJ, Köhler M, Mayr WR, Panzer S, Ohio H, Fischer GF. Genotyping of the human platelet antigen systems 1 through 5 by multiplex polymerase chain reaction and ligaton-based typing. Transfusion. 1996;36:426-431.
25. Holensteiner A, Walchshofer S, Adler A, Kittl E-M, Mayr WR, Panzer S. Human platelet antigen gene frequencies in the Austrian population. Haemostasis. 1995;25:133-136.
26. A2 (+) individuals. Blood Supply: 1996;88:26a. Abstract.