Malignant transformation of mammary epithelial cells increases expression of leptin and leptin receptor

Endocrine Research

Volumn 33, Issue 3-4, 2008, Pages 111-118

  Sheffield, Lewis ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Cancer; Leptin; Mammory; Receptor; Transformation

Indexed keywords

LEPTIN; LEPTIN RECEPTOR;

ANIMAL CELL; ARTICLE; BREAST CANCER; BREAST CELL; CONTROLLED STUDY; DNA SYNTHESIS; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BIOSYNTHESIS; CELL LINE; CELL TRANSFORMATION; FEMALE; GENE EXPRESSION REGULATION; MAMMARY GLAND; METABOLISM; UDDER;

ANIMALS; CELL LINE; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, NEOPLASTIC; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEPTIN; MAMMARY GLANDS, ANIMAL; MAMMARY GLANDS, HUMAN; MICE; RECEPTORS, LEPTIN;

EID: 63049122838     PISSN: 07435800     EISSN: 15324206     Source Type: Journal    
DOI: 10.1080/07435800802539976     Document Type: Article

References (33)

1. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature. 1994; 372:425-432.
2. Bonnet M, Delavaud C, Laud K, et al. Mammary leptin synthesis, milk leptin and their putative physiological roles. Reprod Nutr Dev 2002; 42:399-413.
3. Bonnet M, Gourdou I, Leroux C, Chilliard Y, Djiane J. Leptin expression in the ovine mammary gland: putative sequential involvement of adipose, epithelial, and myoepithelial cells during pregnancy and lactation. J Anim Sci. 2002; 80:723-728.
4. Laud K, Gourdou I, Belair L, Keisler DH, Djiane J. Detection and regulation of leptin receptor mRNA in ovine mammary epithelial cells during pregnancy and lactation. FEBS Lett 1999; 463:194-198.
5. Smith JL, Sheffield LG. Production and regulation of leptin in bovine mammary epithelial cells. Domest Anim Endocrinol 2002; 22:145-154.
6. Smith-Kirwin SM, O'Connor DM, De Johnston J, Lancey ED, Hassink SG, Funanage VL. Leptin expression in human mammary epithelial cells and breast milk. J Clin Endocrinol Metab 1998; 83:1810-1813.
7. Dieudonne MN, Machinal-Quelin F, Serazin-Leroy V, Leneveu MC, Pecquery R, Giudicelli Y. Leptin mediates a proliferative response in human MCF7 breast cancer cells. Biochem Biophys Res Commun 2002; 293:622-628.
8. Hu X, Juneja SC, Maihle NJ, Cleary MP. Leptin-a growth factor in normal and malignant breast cells and for normal mammary gland development. J Natl Cancer Inst 2002; 94:1704-1711.
9. Laud K, Gourdou I, Pessemesse L, Peyrat JP, Djiane J. Identification of leptin receptors in human breast cancer: functional activity in the T47-D breast cancer cell line. Mol Cell Endocrinol 2002; 188:219-226.
10. Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature 1998; 395:763-770.
11. Houseknecht KL, Baile CA, Matteri RL, Spurlock ME. The biology of leptin: a review. J Anim Sci1998; 76:1405-1420.
12. Caldefie-Chezet F, Damez M, de Latour M, et al. Leptin: a proliferative factor for breast cancer? Study on human ductal carcinoma. Biochem Biophys Res Commun 2005; 334:737-741.
13. Mantzoros CS, Bolhke K, Moschos S, Cramer DW. Leptin in relation to carcinoma in situ of the breast: a study of pre-menopausal cases and controls. Int J Cancer 1999; 80:523-526.
14. Tessitore L, Vizio B, Jenkins O, et al. Leptin expression in colorectal and breast cancer patients. Int J Mol Med 2000; 5:421-426.
15. Ishikawa M, Kitayama J, Nagawa H. Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer. Clin Cancer Res 10:4325-4331.
16. O'Brien SN, Welter BH, Price TM. Presence of leptin in breast cell lines and breast tumors. Biochem Biophys Res Commun 1999; 259:695-698.
17. Sheffield LG. C-Src activation by ErbB2 leads to attachment-independent growth of human breast epithelial cells. Biochem Biophys Res Commun 1998; 250:27-31.
18. Winer J, Jung CK, Shackel I, Williams PM. Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal Biochem 1999; 270:41-49.
19. Yuan JS, Reed A, Chen F, Stewart CN Jr. Statistical analysis of real-time PCR data. BMC Bioinformatics2006; 7:85.
20. Vanderboom RJ, Sheffield LG. Estrogen enhances epidermal growth factor-induced DNA synthesis in mammary epithelial cells. J Cell Physiol 1993; 156:367-372.
21. Gill JL. Design and Analysis of Experiments in the Animal and Medical Sciences. Iowa City, IA: Iowa State University Press; 1978.
22. Sayed-Ahmed A, Kulcsar M, Rudas P, Bartha T. Expression and localisation of leptin and leptin receptor in the mammary gland of the dry and lactating non-pregnant cow. Acta Vet Hung 2004; 52:97-111.
23. Danielsen AJ, Maihle NJ. The EGF/ErbB receptor family and apoptosis. Growth Factors 2000; 20:1-15.
24. Dickson RB, Salomon DS, Lippman ME. Tyrosine kinase receptor-nuclear protooncogene interactions in breast cancer. Cancer Treat Res 1992; 61:249-273.
25. Ernberg IT. Oncogenes and tumor growth factors in breast cancer. A minireview. Acta Oncol 1990; 29:331-334.
26. Lo HW, Hsu SC, Hung MC. EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization. Breast Cancer Res Treat 2006; 95:211-218.
27. Holbro T, Beerli RR, Maurer F, Koziczak M, Barbas CF III, Hynes NE. The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. Proc Natl Acad Sci USA 2003; 100:8933-8938.
28. Hudelist G, Singer CF, Manavi M, Pischinger K, Kubista E, Czerwenka K. Co-expression of ErbBfamily members in human breast cancer: Her-2/neu is the preferred dimerization candidate in nodal-positive tumors. Breast Cancer Res Treat 2003; 80:353-361.
29. Roskoski R Jr. The ErbB/HER receptor protein-tyrosine kinases and cancer. Biochem Biophys Res Commun. 2004; 319:1-11.
30. Rubin I, Yarden Y. The basic biology of HER2. Ann Oncol 2001; 12(suppl 1):S3-S8.
31. Kloek C, Haq AK, Dunn SL, Lavery HJ, Banks AS, Myers MG Jr. Regulation of Jak kinases by intracellular leptin receptor sequences. J Biol Chem 2002; 277:41547-41555.
32. Myers MG Jr. Leptin receptor signaling and the regulation of mammalian physiology. Recent Prog Horm Res 2004; 59:287-304.
33. Bjorbaek C, Uotani S, da Silva B, Flier JS. Divergent signaling capacities of the long and short isoforms of the leptin receptor. J Biol Chem 1997; 272:32686-32695.