The expression of murine double minute 2 (MDM2) on Helicobacter pylori-infected intestinal metaplasia and gastric cancer

Journal of Clinical Biochemistry and Nutrition

Volumn 44, Issue 2, 2009, Pages 196-202

  Nakajima, Noriko ^a   Ito, Yoko ^a   Yokoyama, Kiyoshi ^a   Uno, Akitake ^a   Kinukawa, Noriko ^a   Nemoto, Norimichi ^a   Moriyama, Mitsuhiko ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Gastric cancer; Helicobacter pylori; Intestinal metaplasia; MDM2

Indexed keywords

INTERLEUKIN 16; PROTEIN MDM2;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; CANCER RISK; CELL PROLIFERATION; CHRONIC GASTRITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HELICOBACTER PYLORI; INTESTINE METAPLASIA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; STOMACH BIOPSY; STOMACH CANCER; STOMACH CARCINOGENESIS; STOMACH EPITHELIUM;

HELICOBACTER PYLORI; MURINAE;

EID: 63049111824     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.08-254     Document Type: Article

References (27)

1. Stolte, M. and Meining, A.: Helicobacter pylori gastritis of the gastric carcinoma phenotype: Is histology capable of identifying high-risk gastritis? J. Gastroenterol., 35, Suppl 12, 98-101, 2000.
2. Haruma, K., Kamada, T., Ito, M., Kitadai, Y., Yoshihara, M., Sumii, K., and Kajiyama, G.: Helicobacter pylori infection is a major risk factor for gastric carcinoma in young patients. Scand. J. Gastroenterol., 35, 255-259, 2000.
3. Moss, S.F., Calam, J., Agarwal, B., Wang, S., and Holt, P.R.: Induction of gastric epithelial apoptosis by Helicobacter pylori. Gut, 38, 498-501, 1996.
4. Mannick, E.E., Bravo, L.E., Zarama, G., Realpe, J.L., Zhang, X.J., Ruiz, B., Fontham, E.T., Mera, R., Miller, M.J., and Correa, P.: Inducible nitric oxide synthase, nytrotyrosine, and apoptosis in Helicobacter pylori gastritis: effect of antibiotics and antioxidants. Cancer Res., 56, 3238-3243, 1996.
5. Peek, R.M., Moss, S.F., Tham, K.T., Pérez-Pérez, G.I., Wang, S., Miller, G.G., Atherton, J.C., Holt, P.R., and Blaser, M.J.: Helicobacter pylori cagA+ strains and dissociation of gastric epithelial cell proliferation from apoptosis. J. Natl. Cancer Inst., 89, 863-868, 1997.
6. Jones, N.L., Shannon, P.T., Cutz, E., Yeger, H., and Sherman, P.M.: Increase in proliferation and apoptosis of gastric epithelial cells early in the natural history of Helicobacter pylori infection. Am. J. Pathol., 151, 1675-1703, 1997.
7. Lundgren, A., Trollmo, C., Edebo, A., Svennerholm, A.M., and Lundin, B.S.: Helicobacter pylori-specific CD4+ T cells home to and accumulate in the human Helicobacter pylori-induced gastric mucosa. Infect. Immun., 73, 5612-5619, 2005.
8. Cruikshank, W.W., Kornfeld, H., and Center, D.M.: Interleukin-16. J. Leukoc. Biol., 67, 757-766, 2000.
9. Glass, W.G., Sarisky, R.T., and Vecchio, A.M.: Not-so-sweet sixteen: the role of IL-16 in infectious and immune-mediated inflammatory disease. J. Interferon Cytokine Res., 26, 511-520, 2006.
10. Vousden, K.H.: p53: death star. Cell, 103, 691-694, 2000.
11. Saji, S., Okumura, N., Eguch, H., Nakashima, S., Suzuki, A., Toi, M., Nozawa, Y., Saji, S., and Hayashi, S.: MDM2 enhances the finctionfunction of estrogen receptor alpha in human breast cancer cells. Biochem. Abiophys. Res. Coram., 281,259-265, 2001.
12. Iwakuma, T. and Lozano, G.: MDM2, an introduction. Mol. Cancer Res., 1, 993-1000, 2003.
13. Chen, G., Sordillo, E.M., Ramey, W.G., Reidy, J., Holt, P.R., Krajewski, S., Reed, J.C., Blaser, M.J., and Moss, S.F.: Apotosis in gastric epithelial cells induced by Helicobacter pylori and accompanied by increased expression of BAK. Biochem. Biophys. Res. Commun., 239, 626-32, 1997.
14. Bates, S. and Vousden, K.H.: p53 in signaling checkpoint arrest or apoptosis. Curr. Opin. Genet. Dev., 6, 12-18, 1996.
15. Fox, J.G., Wang, T.C., Rogers, A.B., Poutahidis, T., Ge, Z., Taylor, N., Dangler, C.A., Israel, D.A., Krishna, U., Gaus, K., and Peek, R.M.: Host and microbial constituents influence Helicobacter pylori-induced cancer in a murine model of hypergastrinemia. Gastroenterol., 124, 1879-1890, 2003.
16. Correa, P.: Chronic atrophic gastritis as a precusor of cancer. in Precancerous lesions of the gastrointestinal tract, eds. By Sherlock, P., Morson, B., Barbara, L., and Veronesi, U., Raven Press, New York, New York, USA., pp. 145-153, 1983.
17. Meltzer, P.S.: MDM2 and p53: a question of balance. J. Natl. Cancer Inst., 86, 1265-1266, 1994.
18. Deb, S.P.: Cell cycle regulatory functions of the human oncoprotein MDM2. Mol. Cancer Res., 1, 1009-1016, 2003.
19. Kodama, M., Fujioka, T., Murakami, K., Okimoto, T., Sato, R., Watanabe, K., and Nasu, M.: Eradication of Helicobacter pylori reduced the immunohistochemical detection of p53 and MDM2 in gastric mucosa. J. Gastroenterol. Hepatol., 20, 941-946, 2005.
20. Günther, T., Schneider-Stock, R., Häckel, C., Kasper, H.U., Pross, M., Hackelsberger, A., Lippert, H., and Roessner, A.: Mdm2 gene amplification in gastric cancer correlation with expression of Mdm2 protein and p53 alterations. Mod. Pathol., 13, 621-626, 2000.
21. Tanière, P., Martel-Planche, G., Maurici, D., Lombard-Bohas, C., Scoazec, J., Montesano, R., Berger, F., and Hainaut, P.: Molecular and clinical differences between adenocarcinomas of the esophagus and of the gastric cardia. Am. J. Pathol., 158, 33-40, 2001.
22. Keates, A.C., Castagliuolo, I., Cruickshank, W.W., Qiu, B., Arseneau, K.O., Brazer, W., and Kelly, C.P.: Interleukin-16 is up-regulated in Crohn's disease and participates in TNBS colitis in mice. Gastroenterol., 119, 972-982, 2000.
23. high regulatory T cells reduce T cell transendothelial migration in cancer patients. Eur. J. Immunol., 37, 282-291, 2007.
24. Joe, T., Kataoka, H., Tanida, S., Watanabe, K., Ohshima, T., Sasaki, M., Nakao, H., Ohhara, H., Higashiyama, S., and Ito, M.: Helicobacter pylori-stimulated interleukin-8 (IL-8) promotes cell proliferation through transactivation of epidermal growth factor receptor (EGFR) by disintegrin and metalloproteinase (ADAM) activation. Dig. Dis. Sci., 50, 2081-2089, 2005.
25. Yamaguchi, T., Nakajima, N., Ito, Y., Iwasaki, A., Arakawa, Y., and Kuwayama, H.: Gastric epithelial cell proliferation and apoptosis in Helcobacter pylori-infected mice. Aliment Pharmacol. Ther., 14, Suppl 1, 68-73, 2000.
26. Akai, Y., Nakajima, N., Ito, Y., Matsui, T., Iwasaki, A., and Arakawa, Y.: Green Tea Polyphenols Reduce Gastric Epithelial Cell Proliferation and Apoptosis Stimulated by Helicobacter pylori Infection. J. Clin. Biochem. Nutr., 40, 108-115, 2007.
27. Ohmiya, N., Taguchi, A., Mabuchi, N., Itoh, A., Hirooka, Y., Niwa, Y., and Goto, H.: MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis. J. Clin. Oncol., 24, 4434-4440, 2006.