메뉴 건너뛰기




Volumn 13, Issue 6, 2000, Pages 621-626

Mdm2 gene amplification in gastric cancer correlation with expression of mdm2 protein and p53 alterations

Author keywords

Gastric cancer; Mdm2; P53

Indexed keywords

PROTEIN MDM2; PROTEIN P53;

EID: 0343193103     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3880107     Document Type: Article
Times cited : (70)

References (33)
  • 1
    • 0026740449 scopus 로고
    • Amplification of a gene encoding a p53-associated protein in human sarcomas
    • Oliner JD, Kinzler KW, Melzer PS, George D, Vogelstein B. Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature 1992;358:80-3.
    • (1992) Nature , vol.358 , pp. 80-83
    • Oliner, J.D.1    Kinzler, K.W.2    Melzer, P.S.3    George, D.4    Vogelstein, B.5
  • 2
    • 0027079358 scopus 로고
    • The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein
    • Mietz JA, Unger T, Huibregtse JM, Howley PM. The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. EMBO J 1992;11:5013-20.
    • (1992) EMBO J , vol.11 , pp. 5013-5020
    • Mietz, J.A.1    Unger, T.2    Huibregtse, J.M.3    Howley, P.M.4
  • 3
    • 0026649648 scopus 로고
    • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • Momand J, Zambetti GP, Olson DC, George D, Levine AJ. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 1992;69:1237-45.
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3    George, D.4    Levine, A.J.5
  • 4
    • 0027358723 scopus 로고
    • The HPV-16 E6, and E6-Ap complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • Scheffner M, Huibregtse JM, Vierstra RD, Howley PM. The HPV-16 E6, and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 1993;75:495-505.
    • (1993) Cell , vol.75 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 5
    • 0027109075 scopus 로고
    • p53, guardian of the genome
    • Lane DP. p53, guardian of the genome. Nature 1992;358: 15-6.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 6
    • 0013568829 scopus 로고
    • Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene
    • Chen JD, Lin JY, Levine AJ. Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene. Mol Med 1995;1:141-2.
    • (1995) Mol Med , vol.1 , pp. 141-142
    • Chen, J.D.1    Lin, J.Y.2    Levine, A.J.3
  • 7
    • 0027673764 scopus 로고
    • The p53-mdm2 autoregulatory feedback loop - A paradigm for the regulation of growth control by p53
    • Picksley SM, Lane DP. The p53-mdm2 autoregulatory feedback loop - a paradigm for the regulation of growth control by p53. Bioassays 1993;15:689-90.
    • (1993) Bioassays , vol.15 , pp. 689-690
    • Picksley, S.M.1    Lane, D.P.2
  • 8
    • 0027244853 scopus 로고
    • The p53 mdm-2 autoregulatory feedback loop
    • Wu XW, Bayle JH, Olson D, Levine A. The p53 mdm-2 autoregulatory feedback loop. Genes Dev 1993;7:1126-32.
    • (1993) Genes Dev , vol.7 , pp. 1126-1132
    • Wu, X.W.1    Bayle, J.H.2    Olson, D.3    Levine, A.4
  • 10
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Haupt Y, Maya R, Kazaz A, Oren M. Mdm2 promotes the rapid degradation of p53. Nature 1997;387:296-9.
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 13
    • 0030762728 scopus 로고    scopus 로고
    • P53 gene mutations and expression of p53 and mdm2 proteins in invasive breast carcinoma: A comparative analysis with clinico-pathological factors
    • Günther T, Schneider-Stock R, Ryš J, Niezabitowski A, Roessner A. P53 gene mutations and expression of p53 and mdm2 proteins in invasive breast carcinoma: a comparative analysis with clinico-pathological factors. J Cancer Res Clin Oncol 1997;123:388-94.
    • (1997) J Cancer Res Clin Oncol , vol.123 , pp. 388-394
    • Günther, T.1    Schneider-Stock, R.2    Ryš, J.3    Niezabitowski, A.4    Roessner, A.5
  • 15
    • 0029054396 scopus 로고
    • mdm 2 gene amplification and overexpression in non-small cell lung carcinomas with accumulation of the p53 protein in the absence of p53 gene mutations
    • Marchetti A, Buttitta F, Pellegrini S, Merlo G, Chella A, Angeletti CA, et al. mdm 2 gene amplification and overexpression in non-small cell lung carcinomas with accumulation of the p53 protein in the absence of p53 gene mutations. Diagn Mol Pathol 1995b;4:93-7.
    • (1995) Diagn Mol Pathol , vol.4 , pp. 93-97
    • Marchetti, A.1    Buttitta, F.2    Pellegrini, S.3    Merlo, G.4    Chella, A.5    Angeletti, C.A.6
  • 16
    • 0031657105 scopus 로고    scopus 로고
    • No evidence for functional inactivation of wild-type p53 protein by mdm2 overexpression in gastric carcinogenesis
    • Blok P, Craanen ME, Dekker W, Offerhaus GJA, Tytgat GNJ. No evidence for functional inactivation of wild-type p53 protein by mdm2 overexpression in gastric carcinogenesis. J Pathol 1998;186(1):36-40.
    • (1998) J Pathol , vol.186 , Issue.1 , pp. 36-40
    • Blok, P.1    Craanen, M.E.2    Dekker, W.3    Offerhaus, G.J.A.4    Tytgat, G.N.J.5
  • 18
    • 12644292106 scopus 로고
    • The two histological main types of gastric carcinoma: Diffuse and so-called intestinal type carcinoma. An attempt at a histo-clinical classification
    • Laurén P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand 1965;64:31-94.
    • (1965) Acta Pathol Microbiol Scand , vol.64 , pp. 31-94
    • Laurén, P.1
  • 19
    • 0026769713 scopus 로고
    • An immunochemical analysis of the human nuclear phosphoprotein p53: New monoclonal antibodies and epitope mapping using recombinant p53
    • Vojtesek B, Bàrtek J, Midgley CA, Lane DP. An immunochemical analysis of the human nuclear phosphoprotein p53: new monoclonal antibodies and epitope mapping using recombinant p53. J Immunol Methods 1992;152:237-44.
    • (1992) J Immunol Methods , vol.152 , pp. 237-244
    • Vojtesek, B.1    Bàrtek, J.2    Midgley, C.A.3    Lane, D.P.4
  • 22
    • 0025968683 scopus 로고
    • Analysis of the variable number of tandem repeats locus D1S80 by the polymerase chain reaction followed by high resolution polyacrylamide gel electrophoresis
    • Budowle B, Chakraborty R, Giusti AM, Eisenberg AJ, Allen RC. Analysis of the variable number of tandem repeats locus D1S80 by the polymerase chain reaction followed by high resolution polyacrylamide gel electrophoresis. Am J Hum Genet 1991;48:137-44.
    • (1991) Am J Hum Genet , vol.48 , pp. 137-144
    • Budowle, B.1    Chakraborty, R.2    Giusti, A.M.3    Eisenberg, A.J.4    Allen, R.C.5
  • 23
    • 0024756969 scopus 로고
    • Rapid and sensitive detection of point mutations and DNA polymorphisms using polymerase chain reaction
    • Orita M, Suzuki Y, Sekyia T, Hayashi K. Rapid and sensitive detection of point mutations and DNA polymorphisms using polymerase chain reaction. Genomics 1989;5:874-9.
    • (1989) Genomics , vol.5 , pp. 874-879
    • Orita, M.1    Suzuki, Y.2    Sekyia, T.3    Hayashi, K.4
  • 24
    • 84988101333 scopus 로고
    • Silver staining of DNA in polyacrylamide gels: Linearity and effect of fragment size
    • Goldmann D, Merril CR. Silver staining of DNA in polyacrylamide gels: linearity and effect of fragment size. Electrophoresis 1982;3:24-6.
    • (1982) Electrophoresis , vol.3 , pp. 24-26
    • Goldmann, D.1    Merril, C.R.2
  • 25
  • 29
    • 0027281872 scopus 로고
    • Narrow spectrum and infrequent p53 mutations and absence of mdm2 amplification in Ewing tumours
    • Kovar H, Auinger A, Jug G, Aryee D, Zoubek A, Salzer-Kuntschik M, et al. Narrow spectrum and infrequent p53 mutations and absence of mdm2 amplification in Ewing tumours. Oncogene 1993;8:2683-90.
    • (1993) Oncogene , vol.8 , pp. 2683-2690
    • Kovar, H.1    Auinger, A.2    Jug, G.3    Aryee, D.4    Zoubek, A.5    Salzer-Kuntschik, M.6
  • 30
    • 0027769911 scopus 로고
    • P53 gene mutations and mdm2 amplification are uncommon in primary carcinomas of the uterine cervix
    • Kessis TD, Slebos RJ, Han SM, Shah K, Bosch XF, Munoz N, et al. P53 gene mutations and mdm2 amplification are uncommon in primary carcinomas of the uterine cervix. Am J Pathol 1993;143:1398-405.
    • (1993) Am J Pathol , vol.143 , pp. 1398-1405
    • Kessis, T.D.1    Slebos, R.J.2    Han, S.M.3    Shah, K.4    Bosch, X.F.5    Munoz, N.6
  • 31
    • 0032954882 scopus 로고    scopus 로고
    • Molecular alterations in early gastric carcinomas. No apparent correlation with helicobacter pylori status
    • Blok P, Craanen ME, Offerhaus GJA, Dekker W, Kuipers EJ, Meuwissen SG, et al. Molecular alterations in early gastric carcinomas. No apparent correlation with Helicobacter pylori status. Am J Clin Pathol 1999;111(2):241-7.
    • (1999) Am J Clin Pathol , vol.111 , Issue.2 , pp. 241-247
    • Blok, P.1    Craanen, M.E.2    Offerhaus, G.J.A.3    Dekker, W.4    Kuipers, E.J.5    Meuwissen, S.G.6
  • 33
    • 0028952577 scopus 로고
    • P53 gene mutations and protein nuclear accumulation are early events in intestinal type gastric cancer but late events in diffuse type
    • Ranzani GN, Luinetti O, Padovan LS, Calistri D, Renault B, Burrel M, et al. P53 gene mutations and protein nuclear accumulation are early events in intestinal type gastric cancer but late events in diffuse type. Cancer Epidemiol Biomarkers Prevent 1995;4:223-31.
    • (1995) Cancer Epidemiol Biomarkers Prevent , vol.4 , pp. 223-231
    • Ranzani, G.N.1    Luinetti, O.2    Padovan, L.S.3    Calistri, D.4    Renault, B.5    Burrel, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.