Expression of syndecan-2 in the amoeboid microglial cells and its involvement in inflammation in the hypoxic developing brain

GLIA

Volumn 57, Issue 3, 2009, Pages 336-349

  Kaur, Charanjit ^a   Sivakumar, V ^a   Yip, G W ^a   Ling, E A ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Amoeboid microglial cells; Developing brain; Hypoxia; Inflammatory cytokines; Syndecan 2

Indexed keywords

INTERLEUKIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; NORPHENAZONE; REACTIVE OXYGEN METABOLITE; STROMAL CELL DERIVED FACTOR 1; SYNDECAN 2; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; DRUG DERIVATIVE; PHENAZONE; PHENYLMETHYLPYRAZOLONE; SCAVENGER; SDC2 PROTEIN, RAT;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN HYPOXIA; CELL HYPOXIA; CELL LABELING; CELL SHAPE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORPUS CALLOSUM; CYTOKINE RELEASE; DRUG MECHANISM; ENCEPHALITIS; GENE EXPRESSION; GENE EXPRESSION REGULATION; IMMUNOREACTIVITY; MICROGLIA; NERVE CELL CULTURE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; UPREGULATION; ANIMAL; ANOXIA; CELL CULTURE; CELL MOTION; DRUG EFFECT; FLOW CYTOMETRY; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PATHOLOGY; PHYSIOLOGY;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; ANOXIA; ANTIPYRINE; CELL MOVEMENT; CELLS, CULTURED; CORPUS CALLOSUM; CYTOKINES; FLOW CYTOMETRY; FREE RADICAL SCAVENGERS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICROGLIA; RATS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SYNDECAN-2;

EID: 62949158746     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20764     Document Type: Article

References (55)

1. Alexopoulou AN, Multhaupt HA, Couchman JR. 2007. Syndecans in wound healing, inflammation and vascular biology. Int J Biochem Cell Biol 39:505-528.
2. Banno M, Mizuno T, Kato H, Zhang G, Kawanokuchi J, Wang J, Kuno R, Jin S, Takeuchi H, Suzumura A. 2005. The radical scavenger edaravone prevents oxidative neurotoxicity induced by peroxynitrite and activated microglia. Neuropharmacology 48:283-290.
3. Bandtlow CE, Zimmermann DR. 2000. Proteoglycans in the developing brain: New conceptual insights for old proteins. Physiol Rev 80:1267-1290.
4. Bartlett AH, Hayashida K, Park PW. 2007. Molecular and cellular mechanisms of syndecans in tissue injury and inflammation. Mol Cells 24:153-166.
5. Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
6. Brown LF, Dubin D, Lavigne L, Logan B, Dvorak HF, Van de Water L. 1993. Macrophages and fibroblasts express embryonic fibronectins during cutaneous wound healing. Am J Pathol 142:793-801.
7. Buonocore G, Perrone S, Bracci R. 2001. Free radicals and brain damage in the newborn. Biol Neonate 79:180-186.
8. Carey DJ. 1997. Syndecans: Multifunctional cell-surface co-receptors. Biochem J 327:1-16.
9. Clasper S, Vekemans S, Fiore M, Plebanski M, Wordsworth P, David G, Jackson DG. 1999. Inducible expression of the cell surface heparan sulfate proteoglycan syndecan-2 (fibroglycan) on human activated macrophages can regulate fibroblast growth factor action. J Biol Chem 274:24113-24123.
10. Colton C, Wilt S, Gilbert D, Chernyshev O, Snell J, Dubois-Dalcq M. 1996. Species differences in the generation of reactive oxygen species by microglia. Mol Chem Neuropathol 28:15-20.
11. Decker T, Lohmann-Matthes ML, Gifford GE. 1987. Cell-associated tumor necrosis factor (TNF) as a killing mechanism of activated cytotoxic macrophages. J Immunol 138:957-962.
12. Deng YY, Lu J, Sivakumar V, Ling EA, Kaur C. 2008. Amoeboid microglia in the periventricular white matter induces oligodendrocyte damage through expression of proinflammatory cytokines via MAP kinase signaling pathway in hypoxic neonatal rats. Brain Pathol 18:387-400.
13. Dheen ST, Jun Y, Yan Z, Tay SS, Ling EA. 2005. Retinoic acid inhibits expression of TNF-alpha and iNOS in activated rat microglia. Glia 50:21-31.
14. Dias-Baruffi M, Pereira-da-Silva G, Jamur MC, Roque-Barreira MC. 1998. Heparin potentiates in vivo neutrophil migration induced by IL-8. Glycoconj J 15:523-526.
15. Edwards IJ, Wagner WD, Owens RT. 1990. Macrophage secretory products selectively stimulate dermatan sulfate proteoglycan production in cultured arterial smooth muscle cells. Am J Pathol 136:609-621.
16. Edwards IJ, Xu H, Obunike JC, Goldberg IJ, Wagner WD. 1995. Differentiated macrophages synthesize a heparan sulfate proteoglycan and an oversulfated chondroitin sulfate proteoglycan that bind lipoprotein lipase. Arterioscler Thromb Vasc Biol 15:400-409.
17. Folkerth RD. 2006. Periventricular leukomalacia: Overview and recent findings. Pediatr Dev Pathol 9:3-13.
18. Ford-Perriss M, Turner K, Guimond S, Apedaile A, Haubeck HD, Turnbull J, Murphy M. 2003. Localisation of specific heparan sulfate proteoglycans during the proliferative phase of brain development. Dev Dyn 227:170-184.
19. Giulian D, Baker TJ. 1986. Characterization of ameboid microglia isolated from developing mammalian brain. J Neurosci 6:2163-2178.
20. Gotte M. 2003. Syndecans in inflammation. FASEB J 17:575-591.
21. Götte M, Yip GW. 2006. Heparanase, hyaluronan, and CD44 in cancers: A breast carcinoma perspective. Cancer Res 66:10233-10237.
22. Halden Y, Rek A, Atzenhofer W, Szilak L, Wabnig A, Kungl AJ. 2004. Interleukin-8 binds to syndecan-2 on human endothelial cells. Biochem J 377(Pt 2):533-538.
23. Hartmann U, Maurer P. 2001. Proteoglycans in the nervous system-The quest for functional roles in vivo. Matrix Biol 20:23-35.
24. Haynes RL, Baud O, Li J, Kinney HC, Volpe JJ, Folkerth DR. 2005. Oxidative and nitrative injury in periventricular leukomalacia: A review. Brain Pathol 15:225-233.
25. Hsueh YP, Sheng M. 1999. Regulated expression and subcellular localization of syndecan heparan sulfate proteoglycans and the syndecan-binding protein CASK/LIN-2 during rat brain development. J Neurosci 19:7415-7425.
26. Ikeda T, Xia YX, Kaneko M, Sameshima H, Ikenoue T. 2002. Effect of the free radical scavenger, 3-methyl-1phenyl-2pyrazolin-5-one (MCI-186), on hypoxia-ischemia-induced brain injury in neonatal rats. Neurosci Lett 329:33-36.
27. Iseki K, Hagino S, Mori T, Zhang Y, Yokoya S, Takaki H, Tase C, Murakawa M, Wanaka A. 2002. Increased syndecan expression by pleiotrophin and FGF receptor-expressing astrocytes in injured brain tissue. Glia 39:1-9.
28. Jalkanen M, Elenius K, Salmivitra M. 1992. Syndecan-a cell surface proteoglycan that selectively binds extracellular effector molecules. In: Lane DA, editor. Heparin and related polysaccharides. New York: Plenum Publishing Corp. pp 79-85.
29. Johnston MV. 1996. Hypoxic and ischemic disorders of infants and children. Lecture for 38th meeting of Japanese Society of Child Neurology, Tokyo, Japan, July. Brain Dev 19:235-239.
30. Jones M, Tussey L, Athanasou N, Jackson DG. 2000. Heparan sulfate proteoglycan isoforms of the CD44 hyaluronan receptor induced in human inflammatory macrophages can function as paracrine regulators of fibroblast growth factor action. J Biol Chem 275:7964-7974.
31. Kolset SO, Mann DM, Uhlin-Hansen L, Winberg JO, Ruoslahti E. 1996. Serglycin-binding proteins in activated macrophages and platelets. J Leukoc Biol 59:545-554.
32. Laskin JD, Dokidis A, Gardner CR, Laskin DL. 1991. Changes in sulfated proteoglycan production after activation of rat liver macrophages. Hepatology 14:306-312.
33. Lewis CE, Murdoch C. 2005. Macrophage responses to hypoxia: Implications for tumor progression. Am J Pathol 167:627-635.
34. Ling EA, Wong WC. 1993. The origin and nature of ramified and amoeboid microglia: A historical review and current concepts. Glia 7:9-18.
35. Livak KJ, Schmittgen T. 2001. Analysis of relative gene expression data using real-time quantitative PCR, the 2(-Delta Delta C (T) Method. Methods 24:402-408.
36. Lories V, Cassiman JJ, Van den Berghe H, David G. 1992. Differential expression of cell surface heparan sulfate proteoglycans in human mammary epithelial cells and lung fibroblasts. J Biol Chem 267:1116-1122.
37. Mertens G, Cassiman JJ, Van den Berghe H, Vermylen J, David G. 1992. Cell surface heparan sulfate proteoglycans from human vascular endothelial cells. Core protein characterization and antithrombin III binding properties. J Biol Chem 167:20435-20443.
38. Modrowski D, Basle M, Lomri A, Marie PJ. 2000. Syndecan-2 is involved in the mitogenic activity and signaling of granulocyte-macrophage colony-stimulating factor in osteoblasts. J Biol Chem 275: 9178-9185.
39. Modrowski D, Orosco A, Thévenard J, Fromigué O, Marie PJ. 2005. Syndecan-2 overexpression induces osteosarcoma cell apoptosis: Implication of syndecan-2 cytoplasmic domain and JNK signaling. Bone 37:180-189.
40. Onozaki K, Matsushima K, Aggarwal BB, Oppenheim JJ. 1985. Human interleukin 1 is a cytocidal factor for several tumor cell lines. J Immunol 135:3962-3968.
41. Proudfoot AE, Handel TM, Johnson Z, Lau EK, Li-Wang P, Clark-Lewis I, Borlat F, Wells TN, Kosco-Vilbois MH. 2003. Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines. Proc Natl Acad Sci USA 100:1885-1890.
42. Rachmilewitz J, Tykocinski ML. 1998. Differential effects of chondroitin sulfates A, B on monocyte and B-cell activation: evidence for B-cell activation via a CD44-dependent pathway. Blood 92:223-229.
43. Rosenberg RD, Shworak NW, Liu J, Schwartz JJ, Zhang L. 1997. Heparan sulfate proteoglycans of the cardiovascular system. J Clin Invest 99:2062-2070.
44. Sadir R, Imberty A, Baleux F, Lortat-Jacob H. 2004. Heparan sulfate/ heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/ CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV. J Biol Chem 279:43854-43860.
45. Splettstoesser WD, Schuff-Werner P. 2002. Oxidative stress in phagocytes-" the enemy within". Microsc Res Tech 57:441-455.
46. Taylor CT, Colgan SP. 1999. Therapeutic targets for hypoxia-elicited pathways. Pharmacol Res 16:1498-1505.
47. Tumova S, Woods A, Couchman JR. 2000. Heparan sulfate proteoglycans on the cell surface: Versatile coordinators of cellular functions. Int J Biochem Cell Biol 32:269-288.
48. Volpe JJ. 2001. Neurobiology of periventricular leukomalacia in the premature infant. Pediatr Res 50:553-562.
49. Wallin C, Puka-Sundvall M, Hagberg H, Weber SG, Sandberg M. 2000. Alterations in glutathione and amino acid concentrations after hypoxia-ischemia in the immature rat brain. Brain Res Dev Brain Res 125:51-60.
50. Welin AK, Sandberg M, Lindblom A, Arvidsson P, Nilsson UA, Kjellmer I, Mallard C. 2005. White matter injury following prolonged free radical formation in the 0.65 gestation fetal sheep brain. Pediatr Res 58:100-105.
51. Yeaman C, Rapraeger AC. 1993a. Membrane-anchored proteoglycans of mouse macrophages: P388D1 cells express a syndecan-4-like heparan sulfate proteoglycan and a distinct chondroitin sulfate form. J Cell Physiol 157:413-425.
52. Yeaman C, Rapraeger AC. 1993b. Post-transcriptional regulation of syndecan-1 expression by cAMP in peritoneal macrophages. J Cell Biol 122:941-950.
53. Yip GW, Ferretti P, Copp AJ. 2002. Heparan sulphate proteoglycans and spinal neurulation in the mouse embryo. Development 129:2109-2119.
54. Yip GW, Smollich M, Götte M. 2006. Therapeutic value of glycosaminoglycans in cancer. Mol Cancer Ther 5:2139-2148.
55. Zhang N, Komine-Kobayashi M, Tanaka R, Liu M, Mizuno Y, Urabe T. 2005. Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain. Stroke 36:2220-2225.