Leukocyte dectin-1 expression is differentially regulated in fungal versus polymicrobial sepsis

Critical Care Medicine

Volumn 37, Issue 3, 2009, Pages 1038-1045

  Ozment Skelton, Tammy R ^a   Defluiter, Elizabeth A ^a   Ha, Tuanzhu ^a   Li, Chuanfu ^a   Graves, Bridget M ^a   Ferguson, Donald A ^b   Schweitzer, John B ^b   Preizsner, Johanna ^b   Brown, Gordon D ^d   Gordon, Siamon ^c   Kalbfleisch, John H ^a   Williams, David L ^a  

^a East Tennessee State University   (United States)

^b EAST TENNESSEE STATE UNIVERSITY   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Candida albicans; Dectin 1; Glucan; Leukocytes; Polymicrobial sepsis

Indexed keywords

CYTOKINE; DECTIN 1; GLUCAN; LIPOPOLYSACCHARIDE; MANNAN; MEMBRANE PROTEIN; NERVE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD; CANDIDA ALBICANS; CANDIDIASIS; CONTROLLED STUDY; FLOW CYTOMETRY; FUNGEMIA; LEUKOCYTE; LIGATION; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PERITONEAL CAVITY; PERITONEUM EXUDATE; PHENOTYPE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; REGULATORY MECHANISM; SPLEEN; UNIVERSITY HOSPITAL; ANIMAL; BACTEREMIA; BIOSYNTHESIS; IMMUNOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM;

ANIMALS; BACTEREMIA; FUNGEMIA; LEUKOCYTES; MEMBRANE PROTEINS; MICE; MICE, INBRED ICR; NERVE TISSUE PROTEINS;

EID: 62849098239     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3181968fa0     Document Type: Article

References (35)

1. Oberholzer A, Oberholzer C, Moldawer LL: Sepsis syndromes: Understanding the role of innate and acquired immunity. Shock 2001; 16:83-96
2. Eggimann P, Pittet D: Postoperative fungal infections. Surg Infect 2006; 7(Suppl 2): S53-S56
3. De Pauw BE: Increasing fungal infections in the intensive care unit. Surg Infect 2006; 7(Suppl 2):S93-S96
4. Gordon S: Pattern recognition receptors: doubling up for the innate immune response. Cell 2002; 111:927-930
5. Williams DL, Rice PJ, Herre J, et al: Recognition of fungal glucans by pattern recognition receptors. Recent Develop Carbohydrate Res 2003; 1:49-66
6. Chauhan N, Li D, Singh P, et al: The cell wall of Candida spp. In: Calderone RA, editor. Candida and Candidiasis. 1st ed. Washington, DC: ASM Press; 2002; p. 159-75
7. Williams DL, Ha T, Li C, et al: Inhibiting early activation of tissue nuclear factor-κB and nuclear factor interleukin 6 with (1->3)-β-D-glucan increases long-term survival in polymicrobial sepsis. Surgery 1999; 126:54-65
8. Williams DL, Browder W, McNamee R, et al: Glucan immunomodulation in experimental E. coli sepsis. In: Normann SJ, Sorkin E, editors. Macrophages and Natural Killer Cells. New York: Plenum Publishing Corporation; 1982; p. 701-706
9. Williams DL, Cook JA, Hoffmann EO, et al: Protective effect of glucan in experimentally induced candidiasis. J Reticuloendothel Soc 1978; 23:479-490
10. Brown GD, Gordon S: Immune recognition: A new receptor for beta-glucans. Nature 2001; 413:36-37
11. Willment JA, Gordon S, Brown GD: Characterization of the human β-glucan receptor and its alternatively spliced isoforms. J Biol Chem 2001; 276:43818-43823
12. Taylor PR, Brown GD, Reid DM, et al: The β-glucan receptor, Dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages. J Immunol 2002; 169:3876-3882
13. Brown GD, Herre J, Williams DL, et al: Dectin-1 mediates the biological effects of β-glucans. J Exp Med 2003; 197: 1119-1124
14. Brown GD, Taylor PR, Reid DM, et al: Dectin-1 is a major β-glucan receptor on macrophages. J Exp Med 2002; 296:412
15. Mueller A, Rice PJ, Ensley HE, et al: Receptor binding and internalization of water-soluble (1->3)-beta-D-glucan biologic response modifier in two monocyte/macrophage cell lines. J Immunol 1996; 156: 3418-3425
16. Herre J, Marshall ASJ, Caron E, et al: Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages. Blood 2004; 104:4038-4045
17. Ozment-Skelton TR, Goldman MP, Gordon S, et al: Prolonged reduction of leukocyte membrane-associated Dectin-1 levels following β-glucan administration. J Pharmacol Exp Ther 2006; 318:540-546
18. Hiyoshi M, Tagawa S, Hashimoto S, et al: Evaluation of a new laboratory test measuring plasma (1→3)-β-D-glucan in the diagnosis of Candida deep mycosis: Comparison with a serologic test. Kansenshogaku Zasshi 1999; 73:1-6
19. Gantner BN, Simmons RM, Underhill DM: Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments. EMBO J 2005; 24:1277-1286
20. Taylor PR, Tsoni SV, Willment JA, et al: Dectin-1 is required for β-glucan recognition and control of fungal infection. Nature Immunol 2006; 8:31-38
21. Saijo S, Fujikado N, Furuta T, et al: Dectin-1 is required for host defense against Pneumocystic carinii but not against Candida albicans. Nature Immunol 2006; 8:39-46
22. Williams DL, Li C, Ha T, et al: Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis. J Immunol 2004; 172:449-456
23. Williams DL, Ha T, Li C, et al: Early activation of hepatic NFkB and NF-IL6 in polymicrobial sepsis correlates with bacteremia, cytokine expression and mortality. Ann Surg 1999; 230:95-104
24. Yang S, Chung CS, Ayala A, et al: Differential alterations in cardiovascular responses during the progression of polymicrobial sepsis in the mouse. Shock 2002; 17:55-60
25. Williams DL, McNamee RB, Jones EL, et al: A method for the solubilization of a (1-3)-β-D-glucan isolated from Saccharomyces cerevisiae. Carbohydr Res 1991; 219:203-213
26. Lowman DW, Ferguson DA, Williams DL: Structural characterization of (1->3)-beta-D-glucans isolated from blastospore and hyphal forms of Candida albicans. Carbohydr Res 2003; 388:1491-1496
27. Rogers TJ, Balish E: Immunity to experimental renal candidiasis in rats. Infect Immun 1978; 19:737-740
28. Willment JA, Lin H-H, Reid DM, et al: Dectin-1 expression and function are enhanced on alternatively activated and GM-CSF-treated macrophages and are negatively regulated by IL-10, dexamethasone, and lipopolysaccharide. J Immunol 2003; 171: 4569-4573
29. Huang W, Na L, Fidel PL, et al: Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. J Infect Dis 2004; 190:624-631
30. Brown GD: Dectin-1: A signalling non-TLR pattern-recognition receptor. Nature Rev Immunol 2006; 6:33-43
31. Digby J, Kalbfleisch J, Glenn A, et al: Serum glucan levels are not specific for presence of fungal infections in intensive care unit patients. Clin Diagn Lab Immunol 2003; 10: 882-885
32. Romani L: Immunity to fungal infections. Nat Rev Immunol 2004; 4:1-23
33. Herre J, Gordon S, Brown GD: Dectin-1 and its role in the recognition of β-glucans by macrophages. Mol Immunol 2004; 40: 869-876
34. Herre J, Willment JA, Gordon S, et al: The role of Dectin-1 in antifungal immunity. Crit Rev Immunol 2004; 24:193-203
35. Marchant A, Deviere J, Byl B, et al: Interleukin-10 production during septicaemia. Lancet 1994; 343:707-708