-
1
-
-
23844438197
-
Adenovirus type 5 E4orf3 protein targets the Mre11 complex to cytoplasmic aggresomes
-
Araujo, F. D., T. H. Stracker, C. T. Carson, D. V. Lee, and M. D. Weitzman. 2005. Adenovirus type 5 E4orf3 protein targets the Mre11 complex to cytoplasmic aggresomes. J. Virol. 79:11382-11391.
-
(2005)
J. Virol
, vol.79
, pp. 11382-11391
-
-
Araujo, F.D.1
Stracker, T.H.2
Carson, C.T.3
Lee, D.V.4
Weitzman, M.D.5
-
2
-
-
0021363662
-
Adenovirus type 5 early region 1b gene product is required for efficient shutoff of host protein synthesis
-
Babiss, L. E., and H. S. Ginsberg. 1984. Adenovirus type 5 early region 1b gene product is required for efficient shutoff of host protein synthesis. J. Virol. 50:202-212.
-
(1984)
J. Virol
, vol.50
, pp. 202-212
-
-
Babiss, L.E.1
Ginsberg, H.S.2
-
3
-
-
34250894884
-
Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation
-
Baker, A., K. J. Rohleder, L. A. Hanakahi, and G. Ketner. 2007. Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation. J. Virol. 81:7034-7040.
-
(2007)
J. Virol
, vol.81
, pp. 7034-7040
-
-
Baker, A.1
Rohleder, K.J.2
Hanakahi, L.A.3
Ketner, G.4
-
4
-
-
0023099280
-
Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection
-
Barker, D. D., and A. J. Berk. 1987. Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection. Virology 156:107-121.
-
(1987)
Virology
, vol.156
, pp. 107-121
-
-
Barker, D.D.1
Berk, A.J.2
-
5
-
-
41249100869
-
Advances in the structural understanding of Vif proteins
-
Barraud, P., J. C. Paillart, R. Marquet, and C. Tisne. 2008. Advances in the structural understanding of Vif proteins. Curr. HIV Res. 6:91-99.
-
(2008)
Curr. HIV Res
, vol.6
, pp. 91-99
-
-
Barraud, P.1
Paillart, J.C.2
Marquet, R.3
Tisne, C.4
-
6
-
-
27944464545
-
Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus
-
Berk, A. J. 2005. Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus. Oncogene 24:7673-7685.
-
(2005)
Oncogene
, vol.24
, pp. 7673-7685
-
-
Berk, A.J.1
-
7
-
-
0344188096
-
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
-
Bischoff, J. R., D. H. Kirn, A. Williams, C. Heise, S. Horn, M. Muna, L. Ng, J. A. Nye, A. Sampson-Johannes, A. Fattaey, and F. McCormick. 1996. An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science 274:373-376.
-
(1996)
Science
, vol.274
, pp. 373-376
-
-
Bischoff, J.R.1
Kirn, D.H.2
Williams, A.3
Heise, C.4
Horn, S.5
Muna, M.6
Ng, L.7
Nye, J.A.8
Sampson-Johannes, A.9
Fattaey, A.10
McCormick, F.11
-
8
-
-
40149099594
-
Control of mRNA export by adenovirus E4orf6 and E1B55K proteins during productive infection requires E4orf6 ubiquitin ligase activity
-
Blanchette, P., K. Kindsmuller, P. Groitl, F. Dallaire, T. Speiseder, P. E. Branton, and T. Dobner. 2008. Control of mRNA export by adenovirus E4orf6 and E1B55K proteins during productive infection requires E4orf6 ubiquitin ligase activity. J. Virol. 82:2642-2651.
-
(2008)
J. Virol
, vol.82
, pp. 2642-2651
-
-
Blanchette, P.1
Kindsmuller, K.2
Groitl, P.3
Dallaire, F.4
Speiseder, T.5
Branton, P.E.6
Dobner, T.7
-
9
-
-
0025037997
-
Interaction of adenoviral E4 and Elb products in late gene expression
-
Bridge, E., and G. Ketner. 1990. Interaction of adenoviral E4 and Elb products in late gene expression. Virology 174:345-353.
-
(1990)
Virology
, vol.174
, pp. 345-353
-
-
Bridge, E.1
Ketner, G.2
-
10
-
-
0027193493
-
Adenovirus early region 4 and viral DNA synthesis
-
Bridge, E., S. Medghalchi, S. Ubol, M. Leesong, and G. Ketner. 1993. Adenovirus early region 4 and viral DNA synthesis. Virology 193:794-801.
-
(1993)
Virology
, vol.193
, pp. 794-801
-
-
Bridge, E.1
Medghalchi, S.2
Ubol, S.3
Leesong, M.4
Ketner, G.5
-
11
-
-
40949116686
-
The TORrid affairs of viruses: Effects of mammalian DNA viruses on the PI3K-Akt-mTOR signalling pathway
-
Buchkovich, N. J., Y. Yu, C. A. Zampieri, and J. C. Alwine. 2008. The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K-Akt-mTOR signalling pathway. Nat. Rev. Microbiol. 6:266-275.
-
(2008)
Nat. Rev. Microbiol
, vol.6
, pp. 266-275
-
-
Buchkovich, N.J.1
Yu, Y.2
Zampieri, C.A.3
Alwine, J.C.4
-
12
-
-
0037805689
-
-
Buchsbaum, R. J., B. A. Connolly, and L. A Feig. 2003. Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin. J. Biol. Chem. 278: 18833-18841.
-
Buchsbaum, R. J., B. A. Connolly, and L. A Feig. 2003. Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin. J. Biol. Chem. 278: 18833-18841.
-
-
-
-
13
-
-
0032493285
-
Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton
-
Burnett, P. E., S. Blackshaw, M. M. Lai, I. A. Qureshi, A. F. Burnett, D. M. Sabatini, and S. H. Snyder. 1998. Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton. Proc. Natl. Acad. Sci. USA 95: 8351-8356.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8351-8356
-
-
Burnett, P.E.1
Blackshaw, S.2
Lai, M.M.3
Qureshi, I.A.4
Burnett, A.F.5
Sabatini, D.M.6
Snyder, S.H.7
-
14
-
-
0032563937
-
The ras-related GTPase rac1 regulates a proliferative pathway selectively utilized by G-protein coupled receptors
-
Burstein, E. S., D. J. Hesterberg, J. S. Gutkind, M. R. Brann, E. A. Currier, and T. L. Messier. 1998. The ras-related GTPase rac1 regulates a proliferative pathway selectively utilized by G-protein coupled receptors. Oncogene 17:1617-1623.
-
(1998)
Oncogene
, vol.17
, pp. 1617-1623
-
-
Burstein, E.S.1
Hesterberg, D.J.2
Gutkind, J.S.3
Brann, M.R.4
Currier, E.A.5
Messier, T.L.6
-
15
-
-
0025736296
-
Modified method of mammalian cell synchronization improves yield and degree of synchronization
-
Cao, G., L. M. Liu, and S. F. Cleary. 1991. Modified method of mammalian cell synchronization improves yield and degree of synchronization. Exp. Cell Res. 193:405-410.
-
(1991)
Exp. Cell Res
, vol.193
, pp. 405-410
-
-
Cao, G.1
Liu, L.M.2
Cleary, S.F.3
-
16
-
-
0024340761
-
Modulation of the metabolism and pharmacokinetics of 1-β-D-arabino-furanosylcytosine by 1-β-D-arabinofuranosyluracil in leukemic mice
-
Chandrasekaran, B., R. L. Capizzi, T. E. Kute, T. Morgan, and J. Dimling. 1989. Modulation of the metabolism and pharmacokinetics of 1-β-D-arabino-furanosylcytosine by 1-β-D-arabinofuranosyluracil in leukemic mice. Cancer Res. 49:3259-3266.
-
(1989)
Cancer Res
, vol.49
, pp. 3259-3266
-
-
Chandrasekaran, B.1
Capizzi, R.L.2
Kute, T.E.3
Morgan, T.4
Dimling, J.5
-
17
-
-
0029890229
-
The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Racl
-
Chou, M. M., and J. Blenis. 1996. The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Racl. Cell 85:573-583.
-
(1996)
Cell
, vol.85
, pp. 573-583
-
-
Chou, M.M.1
Blenis, J.2
-
18
-
-
39849107737
-
Functionally distinct monomers and trimers produced by a viral oncoprotein
-
Chung, S. H., R. S. Weiss, K. K. Frese, B. V. Prasad, and R. T. Javier. 2008. Functionally distinct monomers and trimers produced by a viral oncoprotein. Oncogene 27:1412-1420.
-
(2008)
Oncogene
, vol.27
, pp. 1412-1420
-
-
Chung, S.H.1
Weiss, R.S.2
Frese, K.K.3
Prasad, B.V.4
Javier, R.T.5
-
19
-
-
0242268123
-
Adenoviras E4-34kDa requires active proteasomes to promote late gene expression
-
Corbin-Lickfett, K. A., and E. Bridge. 2003. Adenoviras E4-34kDa requires active proteasomes to promote late gene expression. Virology 315:234-244.
-
(2003)
Virology
, vol.315
, pp. 234-244
-
-
Corbin-Lickfett, K.A.1
Bridge, E.2
-
20
-
-
0031033292
-
Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product
-
Crespo, P., K. E. Schuebel, A. A. Ostrom, J. S. Gutkind, and X. R. Bustelo. 1997. Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product. Nature 385:169-172.
-
(1997)
Nature
, vol.385
, pp. 169-172
-
-
Crespo, P.1
Schuebel, K.E.2
Ostrom, A.A.3
Gutkind, J.S.4
Bustelo, X.R.5
-
21
-
-
0032752063
-
Cellular survival: A play in three Akts
-
Datta, S. R., A. Brunet, and M. E. Greenberg. 1999. Cellular survival: a play in three Akts. Genes Dev. 13:2905-2927.
-
(1999)
Genes Dev
, vol.13
, pp. 2905-2927
-
-
Datta, S.R.1
Brunet, A.2
Greenberg, M.E.3
-
22
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies, S. P., H. Reddy, M. Caivano, and P. Cohen. 2000. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351:95-105.
-
(2000)
Biochem. J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
23
-
-
0033813282
-
Rac1 inhibits TNF-α-induced endothelial cell apoptosis: Dual regulation by reactive oxygen species
-
Deshpande, S. S., P. Angkeow, J. Huang, M. Ozaki, and K. Irani. 2000. Rac1 inhibits TNF-α-induced endothelial cell apoptosis: dual regulation by reactive oxygen species. FASEB J. 14:1705-1714.
-
(2000)
FASEB J
, vol.14
, pp. 1705-1714
-
-
Deshpande, S.S.1
Angkeow, P.2
Huang, J.3
Ozaki, M.4
Irani, K.5
-
24
-
-
18144401244
-
-
Evans, J. D., and P. Hearing. 2005. Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication. J. Virol. 79:6207-6215.
-
Evans, J. D., and P. Hearing. 2005. Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication. J. Virol. 79:6207-6215.
-
-
-
-
25
-
-
0033153464
-
Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions
-
Fackler, O. T., W. Luo, M. Geyer, A. S. Alberts, and B. M. Peterlin. 1999. Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions. Mol. Cell 3:729-739.
-
(1999)
Mol. Cell
, vol.3
, pp. 729-739
-
-
Fackler, O.T.1
Luo, W.2
Geyer, M.3
Alberts, A.S.4
Peterlin, B.M.5
-
26
-
-
0037266099
-
Regulation of mRNA production by the adenoviral E1B 55-kDa and E4 Orf6 proteins
-
Flint, S. J., and R. A. Gonzalez. 2003. Regulation of mRNA production by the adenoviral E1B 55-kDa and E4 Orf6 proteins. Curr. Top. Microbiol. Immunol. 272:287-330.
-
(2003)
Curr. Top. Microbiol. Immunol
, vol.272
, pp. 287-330
-
-
Flint, S.J.1
Gonzalez, R.A.2
-
27
-
-
0037421970
-
Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein
-
Frese, K. K., S. S. Lee, D. L. Thomas, I. J. Latorre, R. S. Weiss, B. A. Glaunsinger, and R. T. Javier. 2003. Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein. Oncogene 22:710-721.
-
(2003)
Oncogene
, vol.22
, pp. 710-721
-
-
Frese, K.K.1
Lee, S.S.2
Thomas, D.L.3
Latorre, I.J.4
Weiss, R.S.5
Glaunsinger, B.A.6
Javier, R.T.7
-
29
-
-
2442664118
-
Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
-
Gao, Y., J. B. Dickerson, F. Guo, J. Zheng, and Y. Zheng. 2004. Rational design and characterization of a Rac GTPase-specific small molecule inhibitor. Proc. Natl. Acad. Sci. USA 101:7618-7623.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7618-7623
-
-
Gao, Y.1
Dickerson, J.B.2
Guo, F.3
Zheng, J.4
Zheng, Y.5
-
30
-
-
33644852717
-
China approves world's first oncolytic virus therapy for cancer treatment
-
Garber, K. 2006. China approves world's first oncolytic virus therapy for cancer treatment. J. Natl. Cancer Inst. 98:298-300.
-
(2006)
J. Natl. Cancer Inst
, vol.98
, pp. 298-300
-
-
Garber, K.1
-
31
-
-
0034597533
-
Interactions of the PDZ-protein MAGI-1 with adenoviras E4-ORF1 and high-risk papillomavirus E6 oncoproteins
-
Glaunsinger, B. A., S. S. Lee, M. Thomas, L. Banks, and R. Javier. 2000. Interactions of the PDZ-protein MAGI-1 with adenoviras E4-ORF1 and high-risk papillomavirus E6 oncoproteins. Oncogene 19:5270-5280.
-
(2000)
Oncogene
, vol.19
, pp. 5270-5280
-
-
Glaunsinger, B.A.1
Lee, S.S.2
Thomas, M.3
Banks, L.4
Javier, R.5
-
32
-
-
0035887255
-
Link of the unique oncogenic properties of adenoviras type 9 E4-ORF1 to a select interaction with the candidate tumor suppressor protein ZO-2
-
Glaunsinger, B. A., R. S. Weiss, S. S. Lee, and R. Javier. 2001. Link of the unique oncogenic properties of adenoviras type 9 E4-ORF1 to a select interaction with the candidate tumor suppressor protein ZO-2. EMBO J. 20:5578-5586.
-
(2001)
EMBO J
, vol.20
, pp. 5578-5586
-
-
Glaunsinger, B.A.1
Weiss, R.S.2
Lee, S.S.3
Javier, R.4
-
33
-
-
0031798440
-
-
Goodrum, F. D., and D. A Ornelles. 1998. p53 status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infection. J. Virol. 72:9479-9490.
-
Goodrum, F. D., and D. A Ornelles. 1998. p53 status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infection. J. Virol. 72:9479-9490.
-
-
-
-
34
-
-
0032838679
-
Roles for the E4 orf6, orf3, and E1B 55-kilodalton proteins in cell cycle-independent adenoviras replication
-
Goodrum, F. D., and D. A. Ornelles. 1999. Roles for the E4 orf6, orf3, and E1B 55-kilodalton proteins in cell cycle-independent adenoviras replication. J. Virol. 73:7474-7488.
-
(1999)
J. Virol
, vol.73
, pp. 7474-7488
-
-
Goodrum, F.D.1
Ornelles, D.A.2
-
35
-
-
0031060333
-
-
Goodrum, F. D., and D. A, Ornelles. 1997. The early region 1B 55-kilodalton oncoprotein of adenoviras relieves growth restrictions imposed on viral replication by the cell cycle. J. Virol. 71:548-561.
-
Goodrum, F. D., and D. A, Ornelles. 1997. The early region 1B 55-kilodalton oncoprotein of adenoviras relieves growth restrictions imposed on viral replication by the cell cycle. J. Virol. 71:548-561.
-
-
-
-
36
-
-
0028225439
-
Identification of an invasioninducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins
-
Habets, G. G., E. H. Scholtes, D. Zuydgeest, R. A. van der Kammen, J. C. Stam, A. Berns, and J. G. Collard. 1994. Identification of an invasioninducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins. Cell 77:537-549.
-
(1994)
Cell
, vol.77
, pp. 537-549
-
-
Habets, G.G.1
Scholtes, E.H.2
Zuydgeest, D.3
van der Kammen, R.A.4
Stam, J.C.5
Berns, A.6
Collard, J.G.7
-
37
-
-
0022381043
-
Adenoviras early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff
-
Halbert, D. N., J. R. Cutt, and T. Shenk. 1985. Adenoviras early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff. J. Virol. 56:250-257.
-
(1985)
J. Virol
, vol.56
, pp. 250-257
-
-
Halbert, D.N.1
Cutt, J.R.2
Shenk, T.3
-
38
-
-
0035859956
-
p70S6 kinase signals cell survival as well as growth, inactivating the proapoptotic molecule BAD
-
Harada, H., J. S. Andersen, M. Mann, N. Terada, and S. J. Korsmeyer. 2001. p70S6 kinase signals cell survival as well as growth, inactivating the proapoptotic molecule BAD. Proc. Natl. Acad. Sci. USA 98:9666-9670.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9666-9670
-
-
Harada, H.1
Andersen, J.S.2
Mann, M.3
Terada, N.4
Korsmeyer, S.J.5
-
39
-
-
0036720983
-
Analysis of the adenoviras E1B-55K-anchored proteome reveals its link to ubiquitination machinery
-
Harada, J. N., A. Shevchenko, D. C. Pallas, and A. J. Berk. 2002. Analysis of the adenoviras E1B-55K-anchored proteome reveals its link to ubiquitination machinery. J. Virol. 76:9194-9206.
-
(2002)
J. Virol
, vol.76
, pp. 9194-9206
-
-
Harada, J.N.1
Shevchenko, A.2
Pallas, D.C.3
Berk, A.J.4
-
40
-
-
33847636341
-
APOBEC-mediated viral restriction: Not simply editing?
-
Holmes, R. K., M. H. Malim, and K. N. Bishop. 2007. APOBEC-mediated viral restriction: not simply editing? Trends Biochem. Sci. 32:118-128.
-
(2007)
Trends Biochem. Sci
, vol.32
, pp. 118-128
-
-
Holmes, R.K.1
Malim, M.H.2
Bishop, K.N.3
-
41
-
-
42449091987
-
Cytidine deaminases as a weapon against retroviruses and a new target for antiviral therapy
-
Izumi, T., K. Shirakawa, and A. Takaori-Kondo. 2008. Cytidine deaminases as a weapon against retroviruses and a new target for antiviral therapy. Mini-Rev. Med. Chem. 8:231-238.
-
(2008)
Mini-Rev. Med. Chem
, vol.8
, pp. 231-238
-
-
Izumi, T.1
Shirakawa, K.2
Takaori-Kondo, A.3
-
42
-
-
0028235924
-
Adenoviras type 9 E4 open reading frame 1 encodes a transforming protein required for the production of mammary tumors in rats
-
Javier, R. T. 1994. Adenoviras type 9 E4 open reading frame 1 encodes a transforming protein required for the production of mammary tumors in rats. J. Virol. 68:3917-3924.
-
(1994)
J. Virol
, vol.68
, pp. 3917-3924
-
-
Javier, R.T.1
-
43
-
-
0037042226
-
Racl prevents cisplatin-induced apoptosis through down-regulation of p38 activation in NIH3T3 cells
-
Jeong, H. G., H. J. Cho, I. Y. Chang, S. P. Yoon, Y. J. Jeon, M. H. Chung, and H. J. You. 2002. Racl prevents cisplatin-induced apoptosis through down-regulation of p38 activation in NIH3T3 cells. FEBS Lett. 518:129-134.
-
(2002)
FEBS Lett
, vol.518
, pp. 129-134
-
-
Jeong, H.G.1
Cho, H.J.2
Chang, I.Y.3
Yoon, S.P.4
Jeon, Y.J.5
Chung, M.H.6
You, H.J.7
-
44
-
-
0018581742
-
Isolation of adenoviras type 5 host range deletion mutants defective for transformation of rat embryo cells
-
Jones, N., and T. Shenk. 1979. Isolation of adenoviras type 5 host range deletion mutants defective for transformation of rat embryo cells. Cell 17: 683-689.
-
(1979)
Cell
, vol.17
, pp. 683-689
-
-
Jones, N.1
Shenk, T.2
-
45
-
-
0017870263
-
Isolation of deletion and substitution mutants of adenoviras type 5
-
Jones, N., and T. Shenk. 1978. Isolation of deletion and substitution mutants of adenoviras type 5. Cell 13:181-188.
-
(1978)
Cell
, vol.13
, pp. 181-188
-
-
Jones, N.1
Shenk, T.2
-
46
-
-
0033815457
-
Multi-PDZ domain protein MUPP1 is a cellular target for both adenoviras E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteins
-
Lee, S. S., B. Glaunsinger, F. Mantovani, L. Banks, and R. T. Javier. 2000. Multi-PDZ domain protein MUPP1 is a cellular target for both adenoviras E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteins. J. Virol. 74:9680-9693.
-
(2000)
J. Virol
, vol.74
, pp. 9680-9693
-
-
Lee, S.S.1
Glaunsinger, B.2
Mantovani, F.3
Banks, L.4
Javier, R.T.5
-
47
-
-
10844280830
-
Adenoviral E1A targets Mdm4 to stabilize tumor suppressor p53
-
Li, Z., C. P. Day, J. Y. Yang, W. B. Tsai, G. Lozano, H. M. Shih, and M. C. Hung. 2004. Adenoviral E1A targets Mdm4 to stabilize tumor suppressor p53. Cancer Res. 64:9080-9085.
-
(2004)
Cancer Res
, vol.64
, pp. 9080-9085
-
-
Li, Z.1
Day, C.P.2
Yang, J.Y.3
Tsai, W.B.4
Lozano, G.5
Shih, H.M.6
Hung, M.C.7
-
48
-
-
0027262606
-
Stabilization of the p53 tumor suppressor is induced by adenoviras 5 E1A and accompanies apoptosis
-
Lowe, S. W., and H. E. Ruley. 1993. Stabilization of the p53 tumor suppressor is induced by adenoviras 5 E1A and accompanies apoptosis. Genes Dev. 7:535-545.
-
(1993)
Genes Dev
, vol.7
, pp. 535-545
-
-
Lowe, S.W.1
Ruley, H.E.2
-
49
-
-
34249784818
-
Adenoviras E4orf6 assembles with Cullin5-ElonginB-ElonginC E3 ubiquitin ligase through an HIV/SIV Vif-like BC-box to regulate p53
-
Luo, K., E. Ehrlich, Z. Xiao, W. Zhang, G. Ketner, and X.-F. Yu. 2007. Adenoviras E4orf6 assembles with Cullin5-ElonginB-ElonginC E3 ubiquitin ligase through an HIV/SIV Vif-like BC-box to regulate p53. FASEB J. 21:1742-1750.
-
(2007)
FASEB J
, vol.21
, pp. 1742-1750
-
-
Luo, K.1
Ehrlich, E.2
Xiao, Z.3
Zhang, W.4
Ketner, G.5
Yu, X.-F.6
-
51
-
-
0029907816
-
Oncogenic potential of the adenoviras E4orf6 protein
-
Moore, M., N. Horikoshi, and T. Shenk. 1996. Oncogenic potential of the adenoviras E4orf6 protein. Proc. Natl. Acad. Sci. USA 93:11295-11301.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11295-11301
-
-
Moore, M.1
Horikoshi, N.2
Shenk, T.3
-
52
-
-
41149099465
-
E4Orf6-E1B-55k-dependent degradation of de novo-generated adeno-associated virus type 5 Rep52 and capsid proteins employs a cullin 5-containing E3 ligase complex
-
Nayak, R., K. D. Farris, and D. J. Pintel. 2008. E4Orf6-E1B-55k-dependent degradation of de novo-generated adeno-associated virus type 5 Rep52 and capsid proteins employs a cullin 5-containing E3 ligase complex. J. Virol. 82:3803-3808.
-
(2008)
J. Virol
, vol.82
, pp. 3803-3808
-
-
Nayak, R.1
Farris, K.D.2
Pintel, D.J.3
-
54
-
-
17144403770
-
Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication
-
O'Shea, C., K. Klupsch, S. Choi, B. Bagus, C. Soria, J. Shen, F. McCormick, and D. Stokoe. 2005. Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication. EMBO J. 24:1211-1221.
-
(2005)
EMBO J
, vol.24
, pp. 1211-1221
-
-
O'Shea, C.1
Klupsch, K.2
Choi, S.3
Bagus, B.4
Soria, C.5
Shen, J.6
McCormick, F.7
Stokoe, D.8
-
55
-
-
25444528296
-
Adenoviras overrides cellular checkpoints for protein translation
-
O'Shea, C. C., S. Choi, F. McCormick, and D. Stokoe. 2005. Adenoviras overrides cellular checkpoints for protein translation. Cell Cycle 4:883-888.
-
(2005)
Cell Cycle
, vol.4
, pp. 883-888
-
-
O'Shea, C.C.1
Choi, S.2
McCormick, F.3
Stokoe, D.4
-
56
-
-
0035836637
-
Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1
-
Otsuki, Y., M. Tanaka, S. Yoshii, N. Kawazoe, K. Nakaya, and H. Sugimura. 2001. Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1. Proc. Natl. Acad. Sci. USA 98:4385-4390.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4385-4390
-
-
Otsuki, Y.1
Tanaka, M.2
Yoshii, S.3
Kawazoe, N.4
Nakaya, K.5
Sugimura, H.6
-
57
-
-
0022622023
-
The adenoviras E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAs
-
Pilder, S., M. Moore, J. Logan, and T. Shenk. 1986. The adenoviras E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAs. Mol. Cell. Biol. 6:470-476.
-
(1986)
Mol. Cell. Biol
, vol.6
, pp. 470-476
-
-
Pilder, S.1
Moore, M.2
Logan, J.3
Shenk, T.4
-
58
-
-
0038574494
-
Replicative oncolytic adenovirases in multimodal cancer regimens
-
Post, D. E., F. R. Khuri, J. W. Simons, and E. G. Van Meir. 2003. Replicative oncolytic adenovirases in multimodal cancer regimens. Hum. Gene Ther. 14:933-946.
-
(2003)
Hum. Gene Ther
, vol.14
, pp. 933-946
-
-
Post, D.E.1
Khuri, F.R.2
Simons, J.W.3
Van Meir, E.G.4
-
59
-
-
0035577765
-
Degradation of p53 by adenoviras E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex
-
Querido, E., P. Blanchette, Q. Yan, T. Kamura, M. Morrison, D. Boivin, W. G. Kaelin, R. C. Conaway, J. W. Conaway, and P. E. Branton. 2001. Degradation of p53 by adenoviras E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex. Genes Dev. 15: 3104-3117.
-
(2001)
Genes Dev
, vol.15
, pp. 3104-3117
-
-
Querido, E.1
Blanchette, P.2
Yan, Q.3
Kamura, T.4
Morrison, M.5
Boivin, D.6
Kaelin, W.G.7
Conaway, R.C.8
Conaway, J.W.9
Branton, P.E.10
-
60
-
-
0030935013
-
Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenoviras-infected cells
-
Querido, E., R. C. Marcellus, A. Lai, R. Charbonneau, J. G. Teodoro, G. Ketner, and P. E. Branton. 1997. Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenoviras-infected cells. J. Virol. 71: 3788-3798.
-
(1997)
J. Virol
, vol.71
, pp. 3788-3798
-
-
Querido, E.1
Marcellus, R.C.2
Lai, A.3
Charbonneau, R.4
Teodoro, J.G.5
Ketner, G.6
Branton, P.E.7
-
61
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
Sarbassov, D. D., S. M. Ali, S. Sengupta, J. H. Sheen, P. P. Hsu, A. F. Bagley, A. L. Markhard, and D. M. Sabatini. 2006. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol. Cell 22:159-168.
-
(2006)
Mol. Cell
, vol.22
, pp. 159-168
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sengupta, S.3
Sheen, J.H.4
Hsu, P.P.5
Bagley, A.F.6
Markhard, A.L.7
Sabatini, D.M.8
-
62
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
Sarbassov, D. D., D. A. Guertin, S. M. Ali, and D. M. Sabatini. 2005. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307:1098-1101.
-
(2005)
Science
, vol.307
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
63
-
-
0032538792
-
Phosphor-ylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2
-
Schuebel, K. E., N. Movilla, J. L. Rosa, and X. R. Bustelo. 1998. Phosphor-ylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2. EMBO J. 17:6608-6621.
-
(1998)
EMBO J
, vol.17
, pp. 6608-6621
-
-
Schuebel, K.E.1
Movilla, N.2
Rosa, J.L.3
Bustelo, X.R.4
-
64
-
-
50949088243
-
Distinct requirements of adenoviras Elb55K protein for degradation of cellular substrates
-
Schwartz, R. A, S. S. Lakdawala, H. D. Eshleman, M. R. Russell, C. T. Carson, and M. D. Weitzman. 2008. Distinct requirements of adenoviras Elb55K protein for degradation of cellular substrates. J. Virol. 82:9043-9055.
-
(2008)
J. Virol
, vol.82
, pp. 9043-9055
-
-
Schwartz1
Lakdawala, R.A.S.S.2
Eshleman, H.D.3
Russell, M.R.4
Carson, C.T.5
Weitzman, M.D.6
-
65
-
-
0034916230
-
PDZ domains and the organization of supramolecular complexes
-
Sheng, M., and C. Sala. 2001. PDZ domains and the organization of supramolecular complexes. Annu. Rev. Neurosci. 24:1-29.
-
(2001)
Annu. Rev. Neurosci
, vol.24
, pp. 1-29
-
-
Sheng, M.1
Sala, C.2
-
66
-
-
4444369683
-
Diverse roles for E4orf3 at late times of infection revealed in an E1B 55-kilodalton protein mutant background
-
Shepard, R. N., and D. A. Ornelles. 2004. Diverse roles for E4orf3 at late times of infection revealed in an E1B 55-kilodalton protein mutant background. J. Virol. 78:9924-9935.
-
(2004)
J. Virol
, vol.78
, pp. 9924-9935
-
-
Shepard, R.N.1
Ornelles, D.A.2
-
67
-
-
0038446941
-
E4orf3 is necessary for enhanced S-phase replication of cell cycle-restricted subgroup C adenoviruses
-
Shepard, R. N., and D. A. Ornelles. 2003. E4orf3 is necessary for enhanced S-phase replication of cell cycle-restricted subgroup C adenoviruses. J. Virol. 77:8593-8595.
-
(2003)
J. Virol
, vol.77
, pp. 8593-8595
-
-
Shepard, R.N.1
Ornelles, D.A.2
-
68
-
-
0037130170
-
Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex
-
Stracker, T. H., C. T. Carson, and M. D. Weitzman. 2002. Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex. Nature 418:348-352.
-
(2002)
Nature
, vol.418
, pp. 348-352
-
-
Stracker, T.H.1
Carson, C.T.2
Weitzman, M.D.3
-
69
-
-
18744362169
-
Serotype-specific reorganization of the Mre11 complex by adenoviral E4orf3 proteins
-
Stracker, T. H., D. V. Lee, C. T. Carson, F. D. Araujo, D. A. Ornelles, and M. D. Weitzman. 2005. Serotype-specific reorganization of the Mre11 complex by adenoviral E4orf3 proteins. J. Virol. 79:6664-6673.
-
(2005)
J. Virol
, vol.79
, pp. 6664-6673
-
-
Stracker, T.H.1
Lee, D.V.2
Carson, C.T.3
Araujo, F.D.4
Ornelles, D.A.5
Weitzman, M.D.6
-
70
-
-
0035099271
-
Epstein-Barr virus nuclear protein EBNA-3C interacts with the human metastatic suppressor Nm23-H1: A molecular link to cancer metastasis
-
Subramanian, C., M. A. Cotter II, and E. S. Robertson. 2001. Epstein-Barr virus nuclear protein EBNA-3C interacts with the human metastatic suppressor Nm23-H1: a molecular link to cancer metastasis. Nat. Med. 7:350-355.
-
(2001)
Nat. Med
, vol.7
, pp. 350-355
-
-
Subramanian, C.1
Cotter II, M.A.2
Robertson, E.S.3
-
71
-
-
21844441602
-
Platelet activating factor induces cytoskeletal reorganization through Rho family pathway in THP-1 macrophages
-
Sumita, C., M. Yamane, T. Matsuda, M. Maeda, T. Nariai, Y. Fujio, and J. Azuma. 2005. Platelet activating factor induces cytoskeletal reorganization through Rho family pathway in THP-1 macrophages. FEBS Lett. 579:4038-4042.
-
(2005)
FEBS Lett
, vol.579
, pp. 4038-4042
-
-
Sumita, C.1
Yamane, M.2
Matsuda, T.3
Maeda, M.4
Nariai, T.5
Fujio, Y.6
Azuma, J.7
-
73
-
-
47749134575
-
-
Ullman, A. J., and P. Hearing. 2008. Cellular proteins PML and Daxx mediate an innate antiviral defense antagonized by the adenovirus E4 ORF3 protein. J. Virol. 82:7325-7335.
-
Ullman, A. J., and P. Hearing. 2008. Cellular proteins PML and Daxx mediate an innate antiviral defense antagonized by the adenovirus E4 ORF3 protein. J. Virol. 82:7325-7335.
-
-
-
-
74
-
-
34247562651
-
-
Ullman, A, J., N. C. Reich, and P. Hearing. 2007. Adenovirus E4 ORF3 protein inhibits the interferon-mediated antiviral response. J. Virol. 81:4744-4752.
-
Ullman, A, J., N. C. Reich, and P. Hearing. 2007. Adenovirus E4 ORF3 protein inhibits the interferon-mediated antiviral response. J. Virol. 81:4744-4752.
-
-
-
-
75
-
-
27944462290
-
Inactivating intracellular antiviral responses during adenovirus infection
-
Weitzman, M. D., and D. A. Ornelles. 2005. Inactivating intracellular antiviral responses during adenovirus infection. Oncogene 24:7686-7696.
-
(2005)
Oncogene
, vol.24
, pp. 7686-7696
-
-
Weitzman, M.D.1
Ornelles, D.A.2
-
77
-
-
33846118836
-
Adenovirus ubiquitin-protein ligase stimulates viral late mRNA nuclear export
-
Woo, J. L., and A. J. Berk. 2007. Adenovirus ubiquitin-protein ligase stimulates viral late mRNA nuclear export. J. Virol. 81:575-587.
-
(2007)
J. Virol
, vol.81
, pp. 575-587
-
-
Woo, J.L.1
Berk, A.J.2
-
78
-
-
0028321891
-
Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: Role of bone stromal cells
-
Wu, H. C., J. T. Hsieh, M. E. Gleave, N. M. Brown, S. Pathak, and L. W. Chung. 1994. Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: role of bone stromal cells. Int. J. Cancer 57:406-412.
-
(1994)
Int. J. Cancer
, vol.57
, pp. 406-412
-
-
Wu, H.C.1
Hsieh, J.T.2
Gleave, M.E.3
Brown, N.M.4
Pathak, S.5
Chung, L.W.6
-
79
-
-
33847389767
-
Clinical trials with oncolytic adenovirus in China
-
Yu, W., and H. Fang. 2007. Clinical trials with oncolytic adenovirus in China. Curr. Cancer Drug Targets 7:141-148.
-
(2007)
Curr. Cancer Drug Targets
, vol.7
, pp. 141-148
-
-
Yu, W.1
Fang, H.2
|