Molecular circuits, biological switches, and nonlinear dose-response relationships

Environmental Health Perspectives

Volumn 110, Issue SUPPL. 6, 2002, Pages 971-978

  Andersen, Melvin E ^a   Yang, Raymond S H ^a   French, C Tenley ^a   Chubb, Laura S ^a   Dennison, James E ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Biological switches; Dose response relationships; Endocrine active compounds; Estrogen; Molecular circuitry; Pharmacodynamic models; Risk assessment; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3,3',4,4',5 PENTACHLOROBIPHENYL; CELL NUCLEUS RECEPTOR; CHEMICAL COMPOUND; DIOXIN; ENVIRONMENTAL CHEMICAL; G PROTEIN COUPLED RECEPTOR; LIGAND; PHOSPHATASE; PHOSPHOTRANSFERASE; POLYCHLORINATED BIPHENYL DERIVATIVE; PROTEIN; TOXIC SUBSTANCE;

CELL ACTIVITY; CELL DIFFERENTIATION; CELL DIVISION; CONCENTRATION (PARAMETERS); DOSE RESPONSE; FEEDBACK SYSTEM; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; NONHUMAN; NONLINEAR SYSTEM; PHENOTYPIC VARIATION; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; SIGNAL TRANSDUCTION; TOXICOLOGY;

EID: 0036989983     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.02110s6971     Document Type: Review

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