Fluorescent benzofurazan-cholic acid conjugates for in vitro assessment of bile acid uptake and its modulation by drugs

ChemMedChem

Volumn 4, Issue 3, 2009, Pages 466-472

  Rohacova, Jana ^a   Marín, M Luisa ^a   Martinez Romero, Alicia ^b   Diaz, Laura ^b   O'Connor, José Enrique ^b   Gomez Lechon, M Jose ^c,d   Donato, M Teresa ^c,d,e   Castell, José V ^c,d,e   Miranda, Miguel A ^a  

^a INSTITUTO DE TECNOLOGÍA QUÍMICA   (Spain)

^b CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^c HOSPITAL UNIVERSITARIO LA FE   (Spain)

^d FIS   (Spain)

^e UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Chlorpromazine; Cholestasis; Flow cytometry; Hepatocytes; Troglitazone

Indexed keywords

4 NITROBENZ 2 OXA 1,3 DIAZOLE; BENZOFURAN DERIVATIVE; BILE ACID CONJUGATE; CHLORPROMAZINE; CHOLIC ACID; CITRATE SODIUM; CYCLOSPORIN A; ORGANIC ANION TRANSPORTER; TAUROCHOLIC ACID; TROGLITAZONE; UNCLASSIFIED DRUG; VALPROIC ACID;

ANIMAL CELL; ARTICLE; CELL SUSPENSION; CHOLESTASIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACCUMULATION; DRUG EFFECT; DRUG POTENCY; FLOW CYTOMETRY; FLUORESCENCE; IN VITRO STUDY; LIVER CELL; LIVER TOXICITY; NONHUMAN; PRIORITY JOURNAL; QUANTUM YIELD; RAT;

EID: 62749087807     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200800383     Document Type: Article

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