Antiepileptic drugs affect neuronal androgen signaling via a cytochrome P450-dependent pathway

Journal of Pharmacology and Experimental Therapeutics

Volumn 322, Issue 2, 2007, Pages 550-559

  Gehlhaus, Marcel ^a   Schmitt, Nina ^a   Volk, Benedikt ^a   Meyer, Ralf P ^a,b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; ANTICONVULSIVE AGENT; CYTOCHROME P450 3A; CYTOCHROME P450 3A11; CYTOCHROME P450 3A2; CYTOCHROME P450 ISOENZYME; KETOCONAZOLE; MESSENGER RNA; PHENOBARBITAL; PHENYTOIN; SMALL INTERFERING RNA;

ANIMAL CELL; ANTICONVULSANT ACTIVITY; ARTICLE; CELL STRAIN; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; GENE SILENCING; HORMONAL REGULATION; HORMONE INHIBITION; HORMONE RESPONSIVE ELEMENT; IN VITRO STUDY; LIVER CELL CULTURE; MOUSE; NERVE CELL EXCITABILITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN VARIANT; RAT; RECEPTOR UPREGULATION; REPORTER GENE; SIGNAL TRANSDUCTION;

ANIMALS; ANTICONVULSANTS; CELL LINE, TUMOR; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CYTOCHROME P-450 CYP3A; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; IMMUNOBLOTTING; ISOENZYMES; KETOCONAZOLE; MEMBRANE PROTEINS; MICE; NERVE GROWTH FACTOR; NEUROFILAMENT PROTEINS; NEURONS; PC12 CELLS; PHENOBARBITAL; PHENYTOIN; RATS; RECEPTORS, ANDROGEN; RESPONSE ELEMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 34547094821     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.120303     Document Type: Article

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