A novel approach for organelle-specific DNA damage targeting reveals different susceptibility of mitochondrial DNA to the anticancer drugs camptothecin and topotecan

Nucleic Acids Research

Volumn 37, Issue 4, 2009, Pages

  De la loza Diaz M C ^a   Wellinger, R E ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; DNA TOPOISOMERASE; MITOCHONDRIAL DNA; TOPOTECAN; ANTINEOPLASTIC AGENT;

ARTICLE; CELL DEATH; CELL GROWTH; CELL NUCLEUS; CELL ORGANELLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; GENE EXPRESSION; GENE LOCATION; GENE SEQUENCE; GENE TARGETING; GROWTH INHIBITION; MITOCHONDRIAL DNA DEPLETION; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SINGLE STRANDED DNA BREAK; YEAST CELL; DRUG EFFECT; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MITOCHONDRION;

SACCHAROMYCES CEREVISIAE;

ANTINEOPLASTIC AGENTS; CAMPTOTHECIN; CELL NUCLEUS; DNA DAMAGE; DNA TOPOISOMERASES, TYPE I, EUKARYOTIC; DNA, MITOCHONDRIAL; MITOCHONDRIA; SACCHAROMYCES CEREVISIAE; TOPOTECAN;

EID: 62549138340     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkn1087     Document Type: Article

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