Alterations in the catalytic activity of yeast DNA topoisomerase I result in cell cycle arrest and cell death

Journal of Biological Chemistry

Volumn 272, Issue 19, 1997, Pages 12801-12808

  Megonigal, Maureen D ^a   Fertala, Jolanta ^a   Bjornsti, Mary Ann ^a,b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CAMPTOTHECIN; DNA; DNA TOPOISOMERASE; FUNGAL PROTEIN; MUTANT PROTEIN; RIBOSOME DNA; THREONINE; TYROSINE;

ARTICLE; CATALYSIS; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DNA PROTEIN COMPLEX; ENZYME ACTIVITY; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; YEAST;

APOPTOSIS; BINDING SITES; CAMPTOTHECIN; CELL CYCLE; DNA DAMAGE; DNA TOPOISOMERASES, TYPE I; G2 PHASE; KINETICS; MUTAGENESIS, SITE-DIRECTED; PHENOTYPE; SACCHAROMYCES CEREVISIAE; STRUCTURE-ACTIVITY RELATIONSHIP; TYROSINE;

EID: 0030962069     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.19.12801     Document Type: Article

References (56)

1. Bjornsti, M.-A. (1991) Curr. Opin. Struct. Biol. 1, 99-103
2. Froelich-Ammon, S. J., and Osheroff, N. (1995) J. Biol. Chem. 270, 21429-21432
3. Sharma, A., and Mondragon, A. (1995) Curr. Opin. Struct. Biol. 5, 39-47
4. Gupta, M., Fujimori, A., and Pommier, Y. (1995) Biochem. Biophys. Acta 1262, 1-14
5. Wang, J. C. (1996) Annu. Rev. Biochem. 65, 635-692
6. Bjornsti, M.-A., Knab, A. M., and Benedetti, P. (1994) Cancer Chemother. Pharmacol. 34, S1-S5
7. Caron, P. R., and Wang, J. C. (1993) in Molecular Biology of DNA Topoisomerases (Andoh, T., Ikeda, H., and Oguro, M., eds) pp. 243-263; CRC Press, Inc., Boca Raton, FL
8. Chen, A., and Liu, L. F. (1994) Annu. Rev. Pharmacol. Toxicol. 34, 191-218
9. Hertzberg, R. P., Caranfa, M. J., and Hecht, S. M. (1989) Biochemistry 28, 4629-4638
10. Hsiang, Y.-H., Hertzberg, R., Hecht, S., and Liu, L. F. (1985) J. Biol. Chem. 260, 14873-14878'
11. Porter, S. E., and Champoux, J. J. (1989) Nucleic Acids Res. 17, 8521-8532
12. Holm, C., Covey, J. M., Kerrigan, D., and Pommier, Y. (1989) Cancer Res. 49, 6365-6368
13. D'Arpa, P., Beardmore, C., and Liu, L. F. (1990) Cancer Res. 50, 6919-6924
14. Tsao, Y.-P., D'Arpa, P., and Liu, L. F. (1992) Cancer Res. 52, 1823-1829
15. Kauh, E. A., and Bjornsti, M.-A. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 6299-6303
16. Bjornsti, M.-A., Benedetti, P., Viglianti, G. A., and Wang, J. C. (1989) Cancer Res. 49, 6318-6323
17. Goto, T., and Wang, J. C. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 7178-7182
18. Thrash, C., Bankier, A. T., Barrell, B. G., and Sternglanz, R. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 4374-4378
19. Benedetti, P., Fiorani, P., Capuani, L., and Wang, J. C. (1993) Cancer Res. 53, 4343-4348
20. Eng, W.-K., Faucette, L., Johnson, R. K., and Sternglanz, R. (1988) Mol. Pharmacol. 34, 755-760
21. Knab, A. M., Fertala, J., and Bjornsti, M.-A. (1993) J. Biol. Chem. 268, 22322-22330
22. Knab, A. M., Fertala, J., and Bjornsti, M.-A. (1995) J. Biol. Chem. 270, 6141-6148
23. Nitiss, J., and Wang, J. C. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 7501-7505
24. Reid, R. J. D., Kauh, E. A., and Bjornsti, M.-A. (1997) J. Biol. Chem. 272, in press
25. Levin, N. A., Bjornsti, M.-A., and Fink, G. R. (1993) Genetics 133, 799-814
26. Rothstein, R. (1991) Methods Enzymol. 194, 281-301
27. Schiestl, R. H., Reynolds, P., Prakash, S., and Prakash, L. (1989) Mol. Cell. Biol. 9, 1882-1896
28. Alani, E., Cao, L., and Kleckner, N. (1987) Genetics 116, 541-545
29. Christman, M. F., Dietrich, F. S., and Fink, G. R. (1988) Cell 55, 413-425
30. Kim, R. A., and Wang, J. C. (1989) Cell 57, 975-985
31. Lynn, R. M., Bjornsti, M.-A., Caron, P. R., and Wang, J. C. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 3559-3563
32. Hill, D. E., Oliphant, A. R., and Struhl, K. (1987) Methods Enzymol. 155, 558-568
33. Bjornsti, M.-A., and Wang, J. C. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 8971-8975
34. Sikorski, R., and Hieter, P. (1989) Genetics 122, 19-27
35. Giaever, G. N., and Wang, J. C. (1988) Cell 55, 849-856
36. Johnston, L. H., and Williamson, D. H. (1978) Mol. Gen. Genet. 164, 217-225
37. Bonven, B. J., Gocke, E., and Westergaard, O. (1985) Cell 41, 541-551
38. Pringle, J. R., Adams, A. E. M., Drubin, D. G., and Haarer, B. K. (1991) Methods Enzymol. 194, 565-602
39. Holm, C., Stearns, T., and Botstein, D. (1989) Mol. Cell. Biol. 9, 159-168
40. Eng, W.-K., Pandit, S. D., and Sternglanz, R. (1989) J. Biol. Chem. 264, 13373-13376
41. Madden, K. R., and Champoux, J. J. (1992) Cancer Res. 52, 525-532
42. Brown, M. T., Goetsch, L., and Hartwell, L. H. (1993) J. Cell Biol. 123, 387-403
43. Lydall, D., and Weinert, T. (1996) Current Opin. Genet. Dev. 6, 4-11
44. Weinert, T. A., Kiser, G. L., and Hartwell, L. H. (1994) Genes Dev. 8, 652-665
45. Weinert, T., and Hartwell, L. H. (1993) Genetics 134, 63-80
46. Tanizawa, A., Kohn, K. W., Kohlhagen, G., Leteurte, F., and Pommier, Y. (1995) Biochemistry 34, 7200-7206
47. Kubota, N., Kanazawa, F., Nishio, K., Takeda, Y., Ohmori, T., Fujiwara, T., Terashiman, Y., and Saijo, N. (1992) Biochem. Biophys. Res. Commun. 188, 571-577
48. Lue, N., Sharma, A., Mondragon, A., and Wang, J. C. (1995) Structure 3, 1315-1322
49. Rubin, E., Pantazis, P., Bharti, A., Toppmeyer, D., Giovanclla, B., and Kufe, D. (1994) J. Biol. Chem. 269, 2433-2439
50. Caserta, M., Camilloni, G., Venditti, S., Venditti, P., and Di Mauro, E. (1994) J. Cell. Biochem. 55, 93-97
51. Sandell, L. L., and Zakian, V. A. (1993) Cell 75, 729-739
52. Bennett, C., Lewis, A. L., Baldwin, K. K., and Resnick, M. A. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 5613-5617
53. Boschelli, F. (1994) Mol. Cell. Biol. 14, 6409
54. Zhu, J., and Schiestl, R. H. (1996) Mol. Cell. Biol. 16, 1805-1812
55. Felix, C. A., Lange, B. J., Hosler, M. R., Fertala, J., and Bjornsti, M. A. (1995) Cancer Res. 55, 4287-4292
56. Allen, J. B., Zhou, Z., Siede, W., Friedberg, E. C., and Elledge, S. J. (1994) Genes Dev. 8, 2416-2428