Gene expression profile of multipotent mesenchymal stromal cells: Identification of pathways common to TGFβ3/BMP2-induced chondrogenesis

Cloning and Stem Cells

Volumn 11, Issue 1, 2009, Pages 61-75

  Mrugala, Dominique ^a,b   Dossat, Nadège ^b   Ringe, Jochen ^c   Delorme, Bruno ^a   Coffy, Amandine ^b   Bony, Claire ^a,b   Charbord, Pierre ^a   Häupl, Thomas ^c   Daures, Jean Pierre ^b   Noël, Danièle ^a,b,e   Jorgensen, Christian ^a,b,d  

^a INSERM   (France)

^b UNIV MONTPELLIER   (France)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d LAPEYRONIE HOSPITAL   (France)

^e HÔPITAL SAINT ELOI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; TRANSFORMING GROWTH FACTOR BETA3;

ADIPOCYTE; ALGORITHM; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ADHESION; CELL DIFFERENTIATION; CELL PROLIFERATION; CHONDROGENESIS; CONTROLLED STUDY; DNA FINGERPRINTING; DNA MICROARRAY; EMBRYO DEVELOPMENT; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; HYPERTROPHY; KINETICS; MESENCHYME; MULTIPOTENT STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOBLAST; PRIORITY JOURNAL; STROMA CELL; TIME;

BONE MORPHOGENETIC PROTEIN 2; CHONDROCYTES; CHONDROGENESIS; GENE EXPRESSION PROFILING; HUMANS; MESENCHYMAL STEM CELLS; MULTIPOTENT STEM CELLS; SIGNAL TRANSDUCTION; STROMAL CELLS; TISSUE ENGINEERING; TRANSFORMING GROWTH FACTOR BETA3;

EID: 62349133990     PISSN: 15362302     EISSN: None     Source Type: Journal    
DOI: 10.1089/clo.2008.0070     Document Type: Article

References (52)

1. Ahmed, N., Dreier, R., Gopferich, A., et al. (2007). Soluble signalling factors derived from differentiated cartilage tissue affect chondrogenic differentiation of rat adult marrow stromal cells. Cell Physiol. Biochem. 20, 665-678.
2. Aigner, T., Zien, A., Gehrsitz, A., et al. (2001). Anabolic and catabolic gene expression pattern analysis in normal versus osteoarthritic cartilage using complementary DNA-array technology. Arthritis Rheum. 44, 2777-2789.
3. Barry, F.P., and Murphy, J.M. (2004). Mesenchymal stem cells: clinical applications and biological characterization. Int. J. Biochem. Cell. Biol. 36, 568-584.
4. Benz, K., Breit, S., Lukoschek, M., et al. (2002). Molecular analysis of expansion, differentiation, and growth factor treatment of human chondrocytes identifies differentiation markers and growth-related genes. Biochem. Biophys. Res. Commun. 293, 284-292.
5. Boeuf, S., Steck, E., Pelttari, K., et al. (2008). Subtractive gene expression profiling of articular cartilage and mesenchymal stem cells: serpins as cartilage-relevant differentiation markers. Osteoarthritis Cartilage 16, 48-60.
6. Church, V., Nohno, T., Linker, C., et al. (2002). Wnt regulation of chondrocyte differentiation. J. Cell Sci. 115, 4809-4818.
7. Cucchiarini, M., Thurn, T., Weimer, A., et al. (2007). Restoration of the extracellular matrix in human osteoarthritic articular cartilage by overexpression of the transcription factor SOX9. Arthritis Rheum. 56, 158-167.
8. DeLise, A.M., Fischer, L., and Tuan, R.S. (2000). Cellular interactions and signaling in cartilage development. Osteoarthritis Cartilage 8, 309-334.
9. Derfoul, A., Perkins, G.L., Hall, D.J., et al. (2006). Glucocorticoids promote chondrogenic differentiation of adult human mesenchymal stem cells by enhancing expression of cartilage extracellular matrix genes. Stem Cells 24, 1487-1495.
10. Djouad, F., Delorme, B., Maurice, M., et al. (2007). Microenvironmental changes during differentiation of mesenchymal stem cells towards chondrocytes. Arthritis Res. Ther. 9, R33.
11. Dominici, M., Le Blanc, K., Mueller, I., et al. (2006). Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 8, 315-317.
12. Esposito, I., Kayed, H., Keleg, S., et al. (2007). Tumor-suppressor function of SPARC-like protein 1/Hevin in pancreatic cancer. Neoplasia 9, 8-17.
13. Figenschau, Y., Knutsen, G., Shahazeydi, S., et al. (2001). Human articular chondrocytes express functional leptin receptors. Biochem. Biophys. Res. Commun. 287, 190-197.
14. Fujimaki, R., Toyama, Y., Hozumi, N., et al. (2006). Involvement of Notch signaling in initiation of prechondrogenic condensation and nodule formation in limb bud micromass cultures. J. Bone Miner. Metab. 24, 191-198.
15. Goldring, M.B. (2006). Update on the biology of the chondrocyte and new approaches to treating cartilage diseases. Best Pract. Res. Clin. Rheumatol. 20, 1003-1025.
16. Goldring, M.B., Tsuchimochi, K., and Ijiri, K. (2006). The control of chondrogenesis. J. Cell Biochem. 97, 33-44.
17. Goto, K., Yabe, K., Suzuki, T., et al. (2008). Gene expression profiles in the articular cartilage of juvenile rats receiving the quinolone antibacterial agent ofloxacin. Toxicology 249, 204-213.
18. Gunn, W.G., Conley, A., Deininger, L., et al. (2006). A crosstalk between myeloma cells and marrow stromal cells stimulates production of DKK1 and interleukin-6: a potential role in the development of lytic bone disease and tumor progression in multiple myeloma. Stem Cells 24, 986-991.
19. Hata, K., Nishijima, K., and Mizuguchi, J. (2007). Role for Btg1 and Btg2 in growth arrest of WEHI-231 cells through arginine methylation following membrane immunoglobulin engagement. Exp. Cell Res. 313, 2356-2366.
20. Haupl, T., Yahyawi, M., Lubke, C., et al. (2007). Gene expression profiling of rheumatoid arthritis synovial cells treated with antirheumatic drugs. J. Biomol. Screen 12, 328-340.
21. Hess, R., Pino, A.M., Rios, S., et al. (2005). High affinity leptin receptors are present in human mesenchymal stem cells (MSCs) derived from control and osteoporotic donors. J. Cell Biochem. 94, 50-57.
22. Ishii, M., Koike, C., Igarashi, A., et al. (2005). Molecular markers distinguish bone marrow mesenchymal stem cells from fibroblasts. Biochem. Biophys. Res. Commun. 332, 297-303.
23. Jacques, C., Recklies, A.D., Levy, A., et al. (2007). HC-gp39 contributes to chondrocyte differentiation by inducing SOX9 and type II collagen expressions. Osteoarthritis Cartilage 15, 138-146.
24. Jeong, J.A., Ko, K.M., Bae, S., et al. (2007). Genome-wide differential gene expression profiling of human bone marrow stromal cells. Stem Cells 25, 994-1002.
25. Jin, E.J., Choi, Y.A., Kyun Park, E., et al. (2007). MMP-2 functions as a negative regulator of chondrogenic cell condensation via down-regulation of the FAK-integrin beta1 interaction. Dev. Biol. 308, 474-484.
26. Karlsson, C., Jonsson, M., Asp, J., et al. (2007). Notch and HES5 are regulated during human cartilage differentiation. Cell Tissue Res. 327, 539-551.
27. Koyama, E., Young, B., Nagayama, M., et al. (2007). Conditional Kif3a ablation causes abnormal hedgehog signaling topography, growth plate dysfunction, and excessive bone and cartilage formation during mouse skeletogenesis. Development 134, 2159-2169.
28. Kruegel, J., Sadowski, B., and Miosge, N. (2008). Nidogen-1 and nidogen-2 in healthy human cartilage and in late-stage osteoarthritis cartilage. Arthritis Rheum. 58, 1422-1432.
29. Kulterer, B., Friedl, G., Jandrositz, A., et al. (2007). Gene expression profiling of human mesenchymal stem cells derived from bone marrow during expansion and osteoblast differentiation. BMC Genomics 8, 70.
30. Lee, R.H., Kim, B., Choi, I., et al. (2004). Characterization and expression analysis of mesenchymal stem cells from human bone marrow and adipose tissue. Cell Physiol. Biochem. 14, 311-324.
31. Lim, M.S., Beaty, M., Sorbara, L., et al. (2002). T-cell/histiocyte-rich large B-cell lymphoma: a heterogeneous entity with derivation from germinal center B cells. Am. J. Surg. Pathol. 26, 1458-1466.
32. Liu, C.H., and Hwang, S. M. (2005). Cytokine interactions in mesenchymal stem cells from cord blood. Cytokine 32, 270-279.
33. Liu, T.M., Martina, M., Hutmacher, D.W., et al. (2007). Identification of common pathways mediating differentiation of bone marrow- and adipose tissue-derived human mesenchymal stem cells into three mesenchymal lineages. Stem Cells 25, 750-760.
34. Manni, I., Tunici, P., Cirenei, N., et al. (2002). Mxi1 inhibits the proliferation of U87 glioma cells through down-regulation of cyclin B1 gene expression. Br. J. Cancer 86, 477-484.
35. Murata, M., Yudo, K., Nakamura, H., et al. (2003). Hypoxia upregulates the expression of angiopoietin-like-4 in human articular chondrocytes: role of angiopoietin-like-4 in the expression of matrix metalloproteinases and cartilage degradation. J. Orthop. Res. 27, 50-57.
36. Nakanishi, K., Chan, Y.S., and Ito, K. (2007). Notch signaling is required for the chondrogenic specification of mouse mesencephalic neural crest cells. Mech. Dev. 124, 190-203.
37. Nishioka, K., Dennis, J.E., Gao, J., et al. (2005). Sustained Wnt protein expression in chondral constructs from mesenchymal stem cells. J. Cell Physiol. 203, 6-14.
38. Ochi, K., Daigo, Y., Katagiri, T., et al. (2003). Expression profiles of two types of human knee-joint cartilage. J. Hum. Genet. 48, 177-182.
39. Parisi, M.S., Gazzerro, E., Rydziel, S., et al. (2006). Expression and regulation of CCN genes in murine osteoblasts. Bone 38, 671-677.
40. Rosa Santos, S.C., Dumon, S., Mayeux, P., et al. (2000). Cooperation between STAT5 and phosphatidylinositol 3-kinase in the IL-3-dependent survival of a bone marrow derived cell line. Oncogene 19, 1164-1172.
41. Schutze, N., Noth, U., Schneidereit, J., et al. (2005). Differential expression of CCN-family members in primary human bone marrow-derived mesenchymal stem cells during osteogenic, chondrogenic and adipogenic differentiation. Cell Commun. Signal 3, 5.
42. Schwable, J., Choudhary, C., Thiede, C., et al. (2005). RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation. Blood 105, 2107-2114.
43. Sekiya, I., Vuoristo, J.T., Larson, B.L., et al. (2002). In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis. Proc. Natl. Acad. Sci. USA 99, 4397-4402.
44. Sekiya, I., Larson, B.L., Vuoristo, J.T., et al. (2005). Comparison of effect of BMP-2, -4, and -6 on in vitro cartilage formation of human adult stem cells from bone marrow stroma. Cell Tissue Res. 320, 269-276.
45. Song, L., Webb, N.E., Song, Y., et al. (2006). Identification and functional analysis of candidate genes regulating mesenchymal stem cell self-renewal and multipotency. Stem Cells 24, 1707-1718.
46. Spagnoli, A., Longobardi, L., and O'Rear, L. (2005). Cartilage disorders: potential therapeutic use of mesenchymal stem cells. Endocr. Dev. 9, 17-30.
47. Taj, M.M., Tawil, R.J., Engstrom, L.D., et al. (2001). Mxi1, a Myc antagonist, suppresses proliferation of DU145 human prostate cells. Prostate 47, 194-204.
48. Untergasser, G., Koch, H.B., Menssen, A., et al. (2002). Characterization of epithelial senescence by serial analysis of gene expression: identification of genes potentially involved in prostate cancer. Cancer Res. 62, 6255-6262.
49. Vibhakar, R., Foltz, G., Yoon, J.G., et al. (2007). Dickkopf-1 is an epigenetically silenced candidate tumor suppressor gene in medulloblastoma. NeuroOncol. 9, 135-144.
50. Ylostalo, J., Smith, J.R., Pochampally, R.R., et al. (2006). Use of differentiating adult stem cells (marrow stromal cells) to identify new downstream target genes for transcription factors. Stem Cells 24, 642-652.
51. Yu, R.Y., Wang, X., Pixley, F.J., et al. (2005). BCL-6 negatively regulates macrophage proliferation by suppressing autocrine IL-6 production. Blood 105, 1777-1784.
52. Zhang, A.H., Rao, J.N., Zou, T., et al. (2007). p53-dependent NDRG1 expression induces inhibition of intestinal epithelial cell proliferation but not apoptosis after polyamine depletion. Am. J. Physiol. Cell Physiol. 293, C379-C389.