Influence of iodide excess and interferon-γ on human primary thyroid cell proliferation, thyroglobulin secretion, and intracellular adhesion molecule-1 and human leukocyte antigen-DR expression

Thyroid

Volumn 19, Issue 3, 2009, Pages 283-291

  Kostic, Irena ^a,b   Toffoletto, Barbara ^b   Fontanini, Elisabetta ^b   Moretti, Massimo ^b   Cesselli, Daniela ^b   Beltrami, Carlo A ^b   Ambesi Impiombato, Francesco S ^b   Curcio, Francesco ^b  

^a UNIVERSITY OF KRAGUJEVAC   (Serbia)

^b UNIVERSITY OF UDINE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DNA; GAMMA INTERFERON; HLA DR ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; POTASSIUM IODIDE; SODIUM IODIDE; THYROGLOBULIN;

ANTIGEN EXPRESSION; ARTICLE; CELL CULTURE; CELL CYCLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; DNA CONTENT; DRUG MEGADOSE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOTHYROIDISM; LOW DRUG DOSE; LYMPHOCYTIC INFILTRATION; MONOLAYER CULTURE; PRIORITY JOURNAL; THYROID CELL; THYROID GLAND;

ANNEXIN A5; CELL CYCLE; CELL PROLIFERATION; DNA, NEOPLASM; FLOW CYTOMETRY; G2 PHASE; HLA-DR ANTIGENS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON-GAMMA; IODIDES; THYROGLOBULIN; THYROID GLAND;

EID: 62249177850     PISSN: 10507256     EISSN: None     Source Type: Journal    
DOI: 10.1089/thy.2008.0295     Document Type: Article

References (44)

1. Kahaly GJ, Dienes HP, Beyer J, Hommel G 1998 Iodide induces thyroid autoimmunity in patients with endemic goitre: a randomised, double-blind, placebo-controlled trial. Eur J Endocrinol 139:290-297.
2. Ambesi-Impiombato FS, Parks LAM, Coon HG 1980 Culture of hormone-dependent functional epithelial cells from rat thyroids. Proc Natl Acad Sci U S A 77:3455-3459.
3. Li M, Boyages SC 1994 Iodide induced lymphocytic thyroiditis in the BB/W rat: evidence of direct toxic effects of iodide on thyroid subcellular structure. Autoimmunity 18:31-40.
4. Becks GP, Eggo MC, Burrow GN 1987 Regulation of differentiated thyroid function by iodide: preferential inhibitory effect of excess iodide on thyroid hormone secretion in sheep thyroid cell cultures. Endocrinology 120:2569-2575.
5. Smerdely P, Pitsiavas V, Boyages SC 1993 Evidence that the inhibitory effects of iodide on thyroid cell proliferation are due to arrest of the cell cycle at G0/G1 and G2/M phases. Endocrinology 133:2881-2888.
6. Eng PH, Cardona GR, Previti MC, Chin WW, Braverman LE 2001 Regulation of the NIS by iodide in FRTL-5 cells. Eur J Endocrinol 144:139-144.
7. Vitale M, di Matola T, D'Ascoli F, Salzano S, Bogazzi F, Fenzi G, Martino E, Rossi G 2000 Iodide excess induces apoptosis in thyroid cells through a p53-independent mechanism involving oxidative stress. Endocrinology 141:598-605.
8. Londei M, Lamb JR, Bottazzo GF, Feldmann M 1984 Epithelial cells expressing aberrant MHC class II determinants can present antigen to cloned human T cells. Nature 312:639-641.
9. Weetman AP, Volkman DJ, Burman KD, Margolick JB, Petrick P, Weintraub BD, Fauci AS 1986 The production and characterization of thyroid-derived T-cell lines in Graves' disease and Hashimoto's thyroiditis. Clin Immunol Immunopathol 39:139-150.
10. Dayan CM, Londei M, Corcoran AE, Grubeck-Loebenstein B, James RF, Rapoport B, Feldman M 1991 Autoantigen recognition by thyroid-infiltrating T cells in Graves disease. Proc Natl Acad Sci U S A 88:7415-7419.
11. Feldmann M, Dayan C, Rapoport B, Londei M 1992 T cell activation and antigen presentation in human thyroid autoimmunity. J Autoimmun 5:115-121.
12. Matsuoka N, Eguchi K, Kawakami A, Tsuboi M, Nakamura H, Kimura H, Ishikawa N, Ito K, Nagataki S 1996 Lack of B7.1/BB1 and B7.2/B70 expression on thyrocytes of patients with Graves' disease. Delivery of costimulatory signals from bystander professional antigen-presenting cells. J Clin Endocrinol Metab 81:4137-4143.
13. Schuppert F, Taniguchi S, Schroder S, Dralle H, von zur Muhlen A, Kohn LD 1996 In vivo and in vitro evidence for iodide regulation of major histocompatibility complex class I and class II expression in Graves' disease. J Clin Endocrinol Metab 81:3622-3628.
14. Bagnasco M, Caretto A, Olive D, Pedini B, Canonica GW, Betterle C 1991 Expression of ICAM-1 on thyroid epithelial cells in Hashimoto's thyroiditis but not in Graves' disease or papillary thyroid cancer. Clin Exp Immunol 83:309-313.
15. Pesce G, Fiorino N, Riccio AM, Montagna P, Torre G, Salmaso C, Altrinetti V, Bagnasco M 2002 Different intrathyroid expression of intercellular adhesion molecule-1 in Hashimoto's thyroiditis and Graves' disease: analysis at mRNA level and association with B7.1 costimulatory molecule. J Endocrinol Invest 25:289-295.
16. Weetman AP, Freeman M, Borysiewicz L, Makgoba MW 1990 Functional analysis of intercellular adhesion molecule-1 expressing human thyroid cells. Eur J Immunol 20:271-275.
17. Ciampolillo A, Napolitano G, Mirakian R, Miyasaki A, Giorgino R, Botazzo GF 1993 ICAM-1 in Graves' disease: contrast between in vivo and in vitro results. Clin Exp Immunol 94:478-485.
18. Roebuck KA, Finnegan A 1999 Regulation of ICAM-1 gene expression. J Leukoc Biol 66:876-888.
19. Bonita RE, Rose NR, Rasooly L, Caturegli P, Burek CL 2002 Adhesion molecules as susceptibility factors in spontaneous autoimmune thyroiditis in the NOD-H2h4 mouse. Exp Mol Pathol 73:155-163.
20. Yamazaki K, Yamada E, Kanaji Y, Yanagisawa T, Kato Y, Takano K, Obara T, Sato K 2003 Genes regulated by thyrotropin and iodide in cultured human thyroid follicles: analysis by cDNA microarray. Thyroid 13:149-158.
21. Pregliasco L, Bocanera L, Krawiec L, Silberscmidt D, Pisarev M, Juvenal G 1996 Effects of iodide on thyroglobulin biosynthesis in FRTL-5 cells. Thyroid 6:319-323.
22. Davies TF, Yang C, Platzer M 1989 The influence of antithyroid drugs and iodine on thyroid cell MHC class II antigen expression. Clin Endocrinol 31:125-135.
23. Sato K, Satoh T, Shizume K, Ozawa M, Han DC, Imamura H, Tsushima T, Demura H, Kanaji Y, Ito Y 1990 Inhibition of 125I organification and thyroid hormone release by interleukin-1, tumor necrosis factor-alpha, and interferon-gamma in human thyrocytes in suspension culture. J Clin Endocrinol Metab 70:1735-1743.
24. Miyazaki A, Shimura H, Endo T, Haraguchi K, Onaya T 1999 Tumor necrosis factor-α and interferon-γ suppress both gene expression and deoxyribonucleic acid-binding of TTF-2 in FRTL-5 cells. Endocrinology 140:4214-4220.
25. Curcio F, Ambesi-Impiombato FS, Perella G, Coon HG 1994 Long-term culture and functional characterization of follicular cells from adult normal human thyroids. Proc Natl Acad Sci U S A 91:9004-9008.
26. Kogai T, Curcio F, Hyman S, Cornford EM, Brent GA, Hershman FM 2000 Induction of follicle formation in long-term cultured normal human thyroid cells treated with thyrotropin stimulates iodide uptake, but not NIS mRNA and protein expression. J Endocrinol 167:125-135.
27. Dugrillon A, Uedelhoven WM, Pisarev MA, Bechtner G, Gartner R 1994 Identification of delta-iodolactone in iodide treated human goiter and its inhibitory effect on proliferation of human thyroid follicles. Horm Metab Res 26:465-469.
28. Gartner R, Dugrillon A 1992 The role of iodine and thyroid cell growth. Thyroidology 4:31-36.
29. Pisarev MA, Bocanera LV, Chester HA, Kleiman de Pisarev DL, Juvenal GJ, Pregliasco LB, Krawiec L 1992 Effect of iodoarachidonates on thyroid FRTL-5 cells growth. Horm Metab Res 24:558-561.
30. Chiovato L, Lapi P, Mariotti S, Del Prete G, De Carli M, Pinchera A 1994 Simultaneous expression of thyroid peroxidase and HLA-DR by human thyroid cells: modulation by thyrotropin, thyroid-stimulating antibody, and IFN-γ. J Clin Endocrinol Metab 79:653-656.
31. Golstein J, Dumont JE 1996 Cytotoxic effects of iodide on thyroid cells: difference between rat thyroid FRTL-5 cells and primary dog thyrocyte responsiveness. J Endocrinol Invest 19:119-126.
32. Pellicciari C, Filippini C, De Grada L, Fuhrman Conti AM, Manfredi Romanini MG 1995 Cell cycle effects of hypertonic stress on various human cells in culture. Cell Biochem Funct 13:1-8.
33. Langer R, Burzler C, Bechtner G, Gartner R 2003 Influence of iodide and iodolactones on thyroid apoptosis. Evidence that apoptosis induced by iodide is mediated by iodolactones in intact porcine thyroid follicles. Exp Clin Endocrinol Diabetes 111:325-329.
34. Feldkamp J, Pascher E, Perniok A, Scherbaum WA 1999 Fas-mediated apoptosis is inhibited by TSH and iodine in moderate concentrations in primary human thyrocytes in vitro. Horm Metab Res 31:355-358.
35. Ajjan RA, Watson RA, Findlay C, Metcalfe RA, Crisp M, Ludgate M, Weetman AP 1998 The sodium iodide symporter gene and its regulation by cytokines found in autoimmunity. J Endocrinol 158:351-358.
36. Oreopoulos GD, Hamilton J, Rizoli SB, Fan J, Lu Z, Li YH, Marshall JC, Kapus A, Rotstein OD 2000 In vivo and in vitro modulation of ICAM-1 expression by hypertonicity. Shock 14:409-414.
37. Lang KS, Weigert C, Braedel S, Fillon S, Palmada M, Schleicher E, Rammensee HG, Lang F 2003 Inhibition of interferon-gamma expression by osmotic shrinkage of peripheral blood lymphocytes. Am J Physiol Cell Physiol 284:C200-208.
38. Wu Z, Biro PA, Mirakian R, Hammond L, Curcio F, Ambesi-Impiombato FS 1999 HLA-DMB expression by thyrocytes: indication of the antigen-processing and possible presenting capability of thyroid cells. Clin Exp Immunol 116:62-69.
39. Montani V, Taniguchi SI, Shong M, Suzuki K, Ohmori M, Giuliani C, Napolitano G, Saji M, Fiorentino B, Reimold AM, Ting JP, Kohn LD, Singer DS 1998 Major histocompatibility class II HLA-DR gene expression in thyrocytes: counter regulation by the class II transactivator and the thyroid Y box protein. Endocrinology 139:280-289.
40. Otten LA, Steimle V, Bontron S, Mach B 1998 Quantitative control of MHC class II expression by the transactivator CIITA. Eur J Immunol 28:473-478.
41. Tang H, Sharp GC, Chen K, Braley-Mullen H 1998 The kinetics of cytokine gene expression in the thyroids of mice developing granulomatous experimental autoimmune thyroiditis. J Autoimmun 11:581-589.
42. Yu S, Sharp GC, Braley-Mullen H 2002 Dual roles for IFN-γ, but not for IL-4, in spontaneous autoimmune thyroiditis in NOD.H-2h4 mice. J Immunol 169:3999-4007.
43. Sharma RB, Alegria JD, Talor MV, Rose NR, Caturegli P, Burek CL 2005 Iodine and IFN-γ synergistically enhance intercellular adhesion molecule 1 expression on NOD.H2h4 mouse thyrocytes. J Immunol 174:7740-7745.
44. Chung J, Park ES, Kim D, Suh M, Chung HK, Kim J, Kim H, Park SJ, Kwon OY, Ro HK, Shong M 2000 Thyrotropin modulates IFN-γ mediated ICAM-1 gene expression by inhibiting JAK1 and STAT1 activation in thyroid cells. Endocrinology 141:2090-2097.