In vivo and in vitro evidence for iodide regulation of major histocompatibility complex class I and class II expression in Graves' disease

Journal of Clinical Endocrinology and Metabolism

Volumn 81, Issue 10, 1996, Pages 3622-3628

  Schuppert, Frank ^a   Taniguchi, Shin Ichi ^b   Schröder, Sören ^c   Dralle, Henning ^d   Von Zur Mühlen, Alexander ^a   Kohn, Leonard D ^b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c Inst Immunol   (Germany)

^d MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE; CYCLIC AMP; ENDOJODIN; GAMMA INTERFERON; HLA DR ANTIGEN; IODIDE; LEVOTHYROXINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; THIAMAZOLE; THYROGLOBULIN ANTIBODY; THYROID ANTIBODY; THYROID PEROXIDASE; THYROTROPIN RECEPTOR; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ANTIGEN EXPRESSION; ARTICLE; CLINICAL ARTICLE; CLINICAL PROTOCOL; CONTROLLED STUDY; ENDEMIC GOITER; FEMALE; GRAVES DISEASE; HASHIMOTO DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRAVENOUS DRUG ADMINISTRATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; PRACTICE GUIDELINE; PRIORITY JOURNAL; THYROID CELL;

ADOLESCENT; ADULT; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELLS, CULTURED; FEMALE; GENE EXPRESSION REGULATION; GENES, MHC CLASS I; GENES, MHC CLASS II; GRAVES DISEASE; HUMANS; IODIDES; MALE; METHIMAZOLE; MIDDLE AGED; RNA, MESSENGER; THYROID GLAND;

EID: 0029848910     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.81.10.3622     Document Type: Article

References (33)

1. Hanafusa T, Pujol Borrell R, Chiovato L, Russell RC, Doniach D, Bottazzo GF. 1983 Aberrant expression of HLA-DR antigen on thyrocytes in Graves' disease: relevance for autoimmunity. Lancet. 2:1111-1115.
2. Bottazzo GF, Pujol Borrell R, Hanafusa T, Feldmann M. 1983 Role of aberrant HLA-DR expression and antigen presentation in induction of endocrine autoimmunity. Lancet. 2:1115-1119.
3. Kohn, L.D., Giuliani, C., Montani, V., et al. 1995 Antireceptor Immunity. In: Rayner D, Champion BR (eds) Thyroid Autoimmunity. Austin/Georgetown, TX: RG Landes Landes; 115-170.
4. Todd I, Londei M, Pujol Borrell R, Mirakian R, Feldmann M, Bottazzo GF. 1986 HLA-D/DR expression on epithelial cells: the finger on the trigger? Ann NY Acad Sci. 475:241-250.
5. Saji M, Moriarty J, Ban T, Singer DS, Kohn LD. 1992 Major histocompatibility complex class I gene expression in rat thyroid cells is regulated by hormones, methimazole, and iodide as well as Interferon. J Clin Endocrinol Metab. 75:871-878.
6. Hokland M, Heron I, Hokland P, Basse P, Berg K. 1986 Measurements of changes in histocompatibility antigens induced by interferons. Methods Enzymol. 119:688-693.
7. Burman P, Totterman TH, Oberg K, Karlsson FA. 1986 Thyroid autoimmunity in patients on long term therapy with leukocyte-derived Interferon. J Clin Endocrinol Metab. 63:1086-1090.
8. Fentiman IS, Balkwill FR, Thomas BS, Russell MJ, Todd I, Bottazzo GF. 1988 An autoimmune aetiology for hypothyroidism following Interferon therapy for breast cancer. Eur J Cancer Clin Oncol. 24:1299-1303.
9. Mayet W-J, Hess G, Gerken G, et al. 1989 Treatment of chronic type B hepatitis with recombinant α-interferon induces autoantibodies not specific for autoimmune chronic hepatitis. Hepatology. 10:24-28.
10. Schuppert F, Müller-Kunert E, Stöcker W, et al. 1996 Cytokines and endocrine system: is it meaningful to monitor more than the thyroid gland? Med Klin. 91:59-65.
11. Mozes E, Kohn LD, Hakim F, Singer DS. 1993 Resistance of MHC class I-deficient mice to experimental systemic lupus erythematosus. Science. 261:91-93.
12. Singer DS, Kohn LD, Zinger H, Mozes E. 1994 Methimazole can prevent development of disease in an experimental model of systemic lupus erythematosus. J Immunol. 153:873-880.
13. Schuppert F, Reiser M, Scheumann GFW, et al. 1993 Expression levels of the thyrotropin receptor gene in autoimmune thyroid disease: coregulation with parameters of thyroid function and inverse relation to major histocompatibility complex classes I and II. J Clin Endocrinol. Metab. 76:1349-1356.
14. Schuppert F, Reiser M, Heldin N-E, et al. 1994 TSH-receptor and leukocyte adhesion molecules in autoimmune thyroid disease: a study of their gene expression by Northern blot analysis and in situ hybridization. Acta Endocrinol (Copenh). 131:480-488.
15. Pohla H, Kuon W, Tabaczewski P, Doerner C, Weiss EH. 1989 Allelic variation in HLA-B and HLA-C sequences and the evolution of the HLA-B alleles. Immunogenetics. 29:297-307.
16. Sekaly RP, Tonnelle C, Strubin M, Mach B, Long EO. 1986 Cell surface expression of class II histocompatibility antigens occurs in the absence of the invariant chain. J Exp Med. 164:1490-1504.
17. Laemmli UK. 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:680-685.
18. Tiran B, Wawschinek O, Eber O, Beham A, Lax S, Dermelj M. 1991 Simple-determination of iodine in small specimens of thyroid tissues. Exp Clin Endocrinol. 98:32-36.
19. Rapoport B, Filetti S, Takai N, Seto P, Halverson G. 1982 Studies on the cyclic AMP response to thyroid stimulating immunoglobulin (TSI) and thyrotropin (TSH) in human thyroid cell monolayers. Metabolism. 31:1159-1167.
20. Kraiem Z, Sadeh O, Yosef M. 1991 Iodide uptake and organification, triiodothyronine secretion, cyclic AMP accumulation and cell proliferation in an optimized system of human thyroid follicles cultured in collagen gel suspended in serum-free medium. J Endocrinol. 131:499-506.
21. Tahara K, Ban T, Minegishi T, Kohn LD. 1991 Immunoglobulins from Graves' disease patients interact with different sites on TSH receptor/LH-CG receptor chimeras than either TSH or immunoglobulins from idiopathic myxedema patients. Biochem Biophys Res Commun. 179:70-77.
22. Piccinini LA, Schachter BS, Davies TF. 1986 HLA-DR alpha chain expression in human thyroid cells. Endocrinology. 118:2611-2613.
23. Aeschimann S, Buergi U, Wagner HE, Kaempf J, Lauber K, Studer H. 1994 Low intrathvroidal iodine concentration in non-endemic human goitres: a consequence rather than a cause of autonomous goitre growth. J Endocrinol. 140:155-164.
24. Braverman, LE. 1986 Iodine-induced thyroid disease. In: Ingbar SH, Braverman (eds) The Thyroid. Philadelphia: Lippincott; 735-746.
25. Davies TF, Yang C, Platzer M. 1989 The influence of antithyroid drugs and iodine on thyroid cell MHC class II antigen expression. Clin Endocrinol (Oxf). 31:125-135.
26. Londei M, Bottazzo GF, Feldmann M. 1985 Human T-cell clones from autoimmune thyroid glands: specific recognition of autologous thyroid cells. Science. 228:85-89.
27. MacKenzie WA, Schwartz AE, Friedman EW, Davies TF. 1987 Intrathyroidal T cell clones from patients with autoimmune thyroid disease. J Clin Endocrinol Metab. 64:818-824.
28. Weetman AP, Freeman M, Borysiewicz LK, Makgoba MW. 1990 Functional analysis of intercellular adhesion molecule-1-expressing human thyroid cells. Eur J Immunol. 20:271-275.
29. Todd I, Pujol Borrell R, Hammond LJ, Bottazzo GF, Feldmann M. 1985 Interferon-gamma induces HLA-DR expression by thyroid epithelium. Clin Exp Immunol. 61:265-273.
30. Matsunaga M, Eguchi K, Fukuda T, et al. 1986 Class II major histocompatibility complex antigen expression and cellular interactions in thyroid glands of Graves' disease. J Clin Endocrinol Metab. 62.723-728.
31. Zakarija M, Hornicek FJ, Levis S, McKenzie JM. 1988 Effects of gamma-interferon and tumor necrosis factor a on thyroid cells: induction of class II antigen and inhibition of growth stimulation. Mol Cell Endocrinol. 58:129-136.
32. Graves P, Neufeld DS, Davies TF. 1989 Differential cytokine regulation of MHC class II and thyroglobin mRNAs in rat thyroid cells. Mol Endocrinol. 3:758-762.
33. Paschke R, Schuppert F, Taton M, Velu T. 1994 Intrathyroidal cytokine gene expression profiles in autoimmune thyroiditis. J Endocrinol. 141:309-315.